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Fujihara S, Mori H, Kobara H, Rafiq K, Niki T, Hirashima M, Masaki T. Galectin-9
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Chiba S, Baghdadi M, Akiba H, Yoshiyama H, Kinoshita I, Dosaka-Akita H,
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Hossain A, Yamaguchi F, Matsunaga T, Hirata Y, Kamitori K, Dong Y, Sui
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Ji XJ, Ma CJ, Wang JM, Wu XY, Niki T, Hirashima M, Moorman JP, Yao ZQ.
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Kadowaki T, Arikawa T, Shinonaga R, Oomizu S, Inagawa H, Soma G, Niki T,
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Kadowaki T, Shimada M, Inagawa H, Kohchi C, Hirashima M, Soma G. (2012) Reconsideration of macrophage and dendritic cell classification. Anticancer Res. 32(6):2257-61.
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Shim JA, Park S, Lee ES, Niki T, Hirashima M, Sohn S. (2012) Galectin-9
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Immunobiology. 217(6):657-66.
Sriwilaijaroen, N., Kondo, S., Yagi, H., Hiramatsu, H., Nakakita, S., Yamada,
K., Ito, H., Hirabayashi, J., Narimatsu, H., Kato, K. and Suzuki, Y. (2012).
Bovine milk whey for preparation of natural N-glycans: structural and quantitative
analysis. Open glycoscience 2012, 5, 41-50
Sumiyoshi W, Nakakita S, Miyanishi N, Yamada K, Hasehira K, Nakakita Y,
Hirabayashi J. (2012). Hypersialylated type-I lactosamine-containing N-glycans
found in Artiodactyla sera are potential xenoantigens. Glycobiology 22(8),
1031-41
Takami H, Taniguchi T, Moriya Y, Kuwahara T, Kanehisa M, Goto S. (2012).
Evaluation method for the potential functionome harbored in the genome
and metagenome. BMC Genomics, 13, 699
K. Terao*, K. Shimizu, N. Miyanishi, S. Shimamoto, T. Suzuki, H. Takao,
F. Oohira (2012). Size-Exclusion SPR Sensor Chip: Application to Detection
of Aggregation and Disaggregation of Biological Particles”, Analyst, 137(9),
2192-2198.
N. Tsurumachi*, H. Okamoto, K. Ishii, H. Kohkami, S. Nakanishi, T. Ishii,
N. Takahashi, C. Dou, P. Wen, and Q. Feng, (2012). Formation of Aggregates
in Nanohybrid Material of Dye Molecules–Titanate Nanosheets”, J. Photochem.
Photobio. A: Chem., 243, 1-6.
T. Ishii*, M. Kenmotsu, K. Tsuge, G. Sakane, Y. Sasaki, M. Yamashita, and
B. K. Breedlove (2012). Luminescence Wavelengths and Energy Level Structure
of Dinuclear Copper Complexes and Related Metal Complexes”, Progress in
Theoretical Chemistry and Physics, B26, Chapter 20, 377-392, Springer,
ISSN: 1567-7354.
Yamada K, Noguchi C, Kamitori K, Dong Y, Hirata Y, Hossain MA, Tsukamoto
I, Tokuda M, Yamaguchi F* (2012). Rare sugar D-allose strongly induces
thioredoxin-interacting protein and inhibits osteoclast differentiation
in Raw264 cells. Nutr Res. 32(2):116-23.
Yamaguchi F, Umeda Y, Shimamoto S, Tsuchiya M, Tokumitsu H, Tokuda M, Kobayashi
R* (2012). S100 proteins modulate protein phosphatase 5 function: a link
between CA2+ signal transduction and protein dephosphorylation. J Biol
Chem. 287(17):13787-98.
Veenstra RG, Taylor PA, Zhou Q, Panoskaltsis-Mortari A, Hirashima M, Flynn
R, Liu D, Anderson AC, Strom TB, Kuchroo VK, Blazar BR. (2012) Contrasting
acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade
dependent upon the presence of donor regulatory T cells. Blood. 120(3):682-90.
Wiersma VR, de Bruyn M, van Ginkel RJ, Sigar E, Hirashima M, Niki T, Nishi
N, Samplonius DF, Helfrich W, Bremer E. (2012) The glycan-binding protein
galectin-9 has direct apoptotic activity toward melanoma cells. J Invest
Dermatol. 132(9):2302-5.
Wakimoto S, Nakayama-Imaohji H, Ichimura M, Morita H, Hirakawa H, Hayashi
T, Yasutomo K, Kuwahara T. (2013) PhoB regulates the survival of Bacteroides
fragilis in peritoneal abscesses. PLoS One, 8, e53829
Yamashita S, Yoshida H, Uchiyama N, Nakakita Y, Nakakita S, Tonozuka T,
Oguma K, Nishikawa A, Kamitori S. (2012). Carbohydrate recognition mechanism
of HA70 from Clostridium botulinum deduced from X-ray structures in complexes
with sialylated oligosaccharides. FEBS Lett. 586, 2404-2410.
Yang ZZ, Grote DM, Ziesmer SC, Niki T, Hirashima M, Novak AJ, Witzig TE,
Ansell SM. (2012) IL-12 upregulates TIM-3 expression and induces T cell
exhaustion in patients with follicular B cell non-Hodgkin lymphoma. J Clin
Invest. 122(4):1271-82.
Yoshida H, Yoshihara A, Teraoka M, Yamashita S, Izumori K, Kamitori S.
(2013). Structure of l-rhamnose isomerase in complexwith l-rhamnopyranose
demonstrates the sugar-ring opening mechanism and the role of a substrate
sub-binding site. FEBS Open Bio 3, 35-40.
Yoshida H, Yamashita S, Teraoka M, Itoh A, Nakakita S, Nishi N, Kamitori
S. (2012). X-ray structure of a protease-resistant mutant form of human
galectin-8 with two carbohydrate recognition domains. FEBS J. 279, 3937-3951.
吉田裕美，玉井栄治，田所隼人，成谷宏文，関谷洋志，岡部昭延，牧純，神鳥成弘，「X-ray structure analysis of a phage
endolysin showing specificity for Clostridium perfringens」第12回日本蛋白質科学会年会,
2012年6月, 名古屋
○R. Tamura, S. Natsuka, S. Nakakita, H. Saitou, N. Miyanishi： Characteristics
of N-glycan structure from main bud of Amorphophallus konjac. 26th International
Carbohydrate Symposium, 2012/ 07/ 21-07/28, Madrid, Spain.
○Yuji Terami, Akihide Yoshihara, Kenji Morimoto, Goro Takata 「Characterization
of L-ribose isomerase from Cellulomonas parahominis MB426 and production
of various rare sugars using this enzyme」『第４回香川大学・チェンマイ大学合同シンポジウム2012』講演要旨集Page85、香川(2012)
○Keiko Uechi, Akihide Yoshihara, Kenji Morimoto, Goro Takata 「Gene cloning
and characterization of novel D-Tagatose 3-epimerase from Mesorhizobium
loti tono」『第４回香川大学・チェンマイ大学合同シンポジウム2012』講演要旨集Page90、香川(2012)
○Sirinan Shompoosang, Kenji Morimoto, Akihide Yoshihara, George W. J. Fleet,
Ken Izumori 「Production of 6-Deoxy-altrose and 6-Deoxy-allose from L-Rhamnose
by Enzymatic Reactions」『第４回香川大学・チェンマイ大学合同シンポジウム2012』講演要旨集Page91、香川(2012)
Y. Haraguchi, M. Yoshimura, Y. Kawanami, R. C. Yanagita, I. Tsukamoto,
Effects of Rare Sugar Fatty Acid Esters on the Tube Formation and Proliferation
of Human Umbilical Vein Endothelial Cells, The fourth Kagawa University-Chang
Mai University Joint Symposium 2012-Healthy Aging and Sustainable Society-,
P. 88 (2012).
○Sato, M., Sakoguchi, H., Shintani, T., Okuma, K., Izumori, K.: The rare
sugar D-psicose extends Caenorhabditis elegans lifespan by increasing oxidative
stress resistance. The 4th Kagawa Univ.-Chiang Mai Univ. Joint Symposium
2012, Kagawa, 9 (2012).
Hiromi Yoshida, Misa Teraoka, Akihide Yoshihara, Ken Izumori and Shigehiro
Kamitori, X-ray structure of L-ribose isomerase in complex with L-ribose
and a deduced catalytic mechanism, 22nd IUBMB 37th FEBS Congress, September
2012, Sevilla (Spain)
○Masahiro Funahashi, Akinari Sonoda, and Tomohiko Ishii, "Vacuum Sublimation
of Liquid-Crystalline Phenylterthiophene Derivative", International
Union of Materials Research Societies - International Conference on Electronic
Materials 2012 (IUMRS-ICEM 2012), Yokohama, Japan.
○S. Hiramatsu, K. Terao, K. Shimizu, T. Suzuki, H. Takao, F. Shimokawa,
F. Oohira: “Fast whole blood testing for detecting biomarkers by size-exclusion
SPR sensing”, Proceedings of The 16th International Conference on Miniaturized
Systems for Chemistry and Life Sciences (MicroTAS2012), 2012/10/28-11/1,
Okinawa, Japan.
○Sirinan Shompoosang, Kenji Morimoto, Akihide Yoshihara, George W. J. Fleet,
Ken Izumori 「Production of 6-deoxy-aldohexoses from L-rhamnose by enzymatic
reactions」『日本生物工学会』講演要旨集Page120、神戸(2012)
Metformin suppresses gene expression for selenoprotein P in hepatocytes
via an AMPK-FoxO3a pathway. ○Takayama H, Misu H, Teraguchi A, Hirose N,
Saito R, Miyamato K, Iwama H, Murao K, Kaneko S, Takamura T: The 9th International
Diabetes Federation Western Pacific Region Congress & 4th Scientific
Meeting of the Asian Association for the study of Diabetes, Kyoto, November,
2012.
R. Yanagita, N. Hashitani, Y. Kawanami, Synthesis and biological activity
of 6-O-acyl-D-allose derivatives, 13th Tetrahedron Symposium Asia edition,
P1.56 (2012)
○神鳥和代、山口文徳、董有毅、ホセインアクラム、平田祐子、片木絢子、野口知里、久岡雅弘、徳田雅明Regulation of thioredoxin
interacting protein (TXNIP) expression by p44/p42 MAPK-p90RSK pathway 第９０回日本生理学会大会、東京,
2013年3月
○Akram Hossain, Fuminori Yamaguchi, Li Sui, Yuko Hirata, Kazuyo Kamitori,
Youyi Dong, Ikuko Tsukamoto, Tetsuo Iida, Yukiyasu Toyoda, Masaaki Tokuda:
Rare sugar D-psicose prevents diabetes development and excess fat accumulation
in type 2 diabetes OLETF rats, 第９０回日本生理学会大会、東京, 2013年3月
Elahi S, Niki T, Hirashima M, Horton H. (2012). Galectin-9 binding to Tim-3
renders activated human CD4+ T cells less susceptible to HIV-1 infection.
Blood, in press.
Gleason MK, Lenvik TR, McCullar V, Felices M, O'Brien MS, Cooley SA, Verneris
MR, Cichocki F, Holman CJ, Panoskaltsis-Mortari A, Niki T, Hirashima M,
Blazar BR, Miller JS. 2012). Tim-3 is an inducible human NK cell receptor
that enhances interferon gamma production in response to galectin-9. Blood,
119, 3064-3072.
Hasehira, K., Miyanishi, N., Sumiyoshi, W., Hirabayashi, .J & Nakakita,
S. (2011). Development of a chemical strategy to produce rare aldohexoses
from ketohexoses using 2-aminopyridine. Carbohydr Res., 346, 2693-2698.
Ikeda, S.*, Gohtani, S., Fukada, K., & K., Amo, Y. (2011). Dielectric
Relaxation and Water Activity in Aqueous Solution of D-Psicose. Jpn. J.
Food Eng., 12, 67-74.
Iqbal, A. J., Sampaio, A. L., Maione, F., Greco, K. V., Niki, T., Hirashima,
M., Perretti, M. & Cooper, D. (2011). Endogenous galectin-1 and acute
inflammation: emerging notion of a galectin-9 pro-resolving effect. Am.
J. Pathol., 178, 1201-1209.
Iwaki, J., Tateno, H., Nishi, N., Minamisawa, T., Nakamura-Tsuruta, S.,
Itakura, Y., Kominami, J., Urashima, T., Nakamura, T. & Hirabayashi,
J.* (2011). The Gal b-(syn)-gauche configuration is required for galectin-recognition
disaccharides. Biochim Biophys Acta. 1810, 643-651.
Jenkinson, S. F., Fleet W. J. G., Nash, R. J., Koike, Y., Adachi, I., Yoshihara,
A., Morimoto, K., & Izumori, K., Kato, A. (2011). Looking-Glass Synergistic
Pharmacological Chaperones: DGJ and L-DGJ from the Enantiomers of Tagatose.
Organic Letters. 13, 4064-4067.
Kadowaki T, Inagawa H, Kohchi C, Hirashima M, Soma G. (2011). Functional
characterization of lipopolysaccharide derived from symbiotic bacteria
in rice as a macrophage-activating substance. Anticancer Res., 31, 2467-2476.
Kadowaki T, Arikawa T, Shinonaga R, Oomizu S, Inagawa H, Soma G, Niki T,
Hirashima M (2012). Galectin-9 signaling prolongs survival in murine lung-cancer
by inducing macrophages to differentiate into plasmacytoid dendritic cell-like
macrophages. Clin Immunol, 143, 296-307.
Kamitori, S.* Ueda, A. Tahara,Y., Yoshida,H., Ishii, T. & Uenishi,
J. (2011). Crystal structures of rare disaccharides, alpha-D-glucopyranosyl-beta-D-psicofuranoside,
and alpha-D-galactopyranosyl-beta-D-psicofuranoside. Carbohydrate Res.,
346, 1182-1185.
Katoh S, Oomizu S, Niki T, Shimizu H, Obase Y, Korenaga M, Oka M, Hirashima
M. (2012). Possible regulatory role of galectin-9 on Ascaris suum-induced
eosinophilic lung inflammation in mice. Int Arch Allergol Immunol, in press.
Kawanami, Y., Hoshino, K. & Tsunoi, W. (2011) Enantioselective reduction
of trifluoromethyl ketones using an oxazaborolidine catalyst generated
in situ from a chiral lactum alcohol. Tetrahedron:Asymmetry, 22, 1464-1466
Kawanami, Y., Yudai, M., Kiguchi, K., Harauchi, Y. & Yanagita, R. C.
(2011). Enantioselective reduction of a,b-enones using an oxazaborolidine
catalyst generated in situ from a chiral lactum alcohol. Tetrahedron:Asymmetry,
22, 1891-1894.
Kojima K, Arikawa T, Saita N, Goto E, Tsumura S, Tanaka R, Masunaga A,
Niki T, Oomizu S, Hirashima M, Kohrogi H (2011). Galectin-9 attenuates
acute lung injury by expanding CD14- plasmacytoid dendritic cell-like macrophages.
Am J Respir Crit Care Med, 184, 328-339
Lv K, Xu W, Wang C, Niki T, Hirashima M & Xiong S. (2011). Galectin-9
administration ameliorates CVB3 induced myocarditis by promoting the proliferation
of regulatory T cells and alternatively activated Th2 cells. Clin Immunol,140,
92-101.
Nakayama-Imaohji, H., Ichimura, M., Iwasa, T., Okada, N., Ohnishi, Y. &
Kuwahara, T.* (2012). Characterization of a gene cluster for sialoglycoconjugate
utilization in Bacteroides fragilis. J Med Invest., in press.
Nariya, H.,* Miyata, S., Kuwahara, T. & Okabe, A. (2011). Development
and characterization of a xylose-inducible gene expression system for Clostridium
perfringens. Appl Environ Microbiol, 77, 8439-8441.
Oomizu, S., Arikawa, T., Niki, T., Kadowaki, T., Ueno, M., Nishi, N., Yamauchi,
A. & Hirashima, M.* (2012). Galectin-9 suppresses Th17 cell development
in an IL-2-dependent but Tim-3-independent manner. Clin Immunol . in press.
Natsuka, S., Hirohata, Y., Nakakita, S., Sumiyoshi, W. & Hase, S. (2011).
Structural analysis of N-glycans of the planarian Dugesia japonica. FEBS
J., 278, 452-460.
Reddy PB, Sehrawat S, Suryawanshi A, Rajasagi NK, Mulik S, Hirashima M,
Rouse BT (2011). Influence of galectin-9/Tim-3 interaction on herpes simplex
virus-1 latency. J Immunol,187, 5745-5755
Sakai, K., Kawata, E., Ashihara, E., Nakagawa, Y., Yamauchi, A., Yao H.,
Nagao R., Tanaka R., Yokota A., Takeuchi, M., Hirai, H., Kimura S., Hirashima,
M., Yoshimura, N. & Maekawa, T. (2011). Galectin-9 ameliorates acute
GVH disease through the induction of T-cell apoptosis. Eur J Immunol, 41,
67-75.
Shim JA, Park S, Lee ES, Niki T, Hirashima M, Sohn S (2012). Galectin-9
ameliorates herpes simplex-induced inflammation through apoptosis. Immunobiology,
in press.
Takata, G., Uechi, K., Taniguchi, E., Kanbara, Y., Yoshihara, A., Morimoto,
K. &Izumori, K. (2011). Characterization of Mesorhizobium loti L-rhamnose
isomerase and its application to L-talose production. Bioscience Biotechnology
Biochemistry, 75, 1006-1009.
Terao, K.,* Kakita, C., Nagase, N., Miyanishi, N. Suzuki, T., Takao, H.,
Shimokawa, F. & Oohira, F. (2012). Evaluation of Electrodeposited Gold
Nanostructures for Applications in QCM Sensing” Analytical Sciences, in
press.
Vega-Carrascal, I., Reeves, E. P., Niki, T., Arikawa, T., McNally, P.,
O'Neill, S. J., Hirashima, M, & McElvaney, N. G. (2011). Dysregulation
of TIM-3-galectin-9 pathway in the cystic fibrosis airways. J. Immunol.,186,
2897-2909.
Yamada, K., Noguchi, C., Kamitori, K., Dong, Y., Hirata ,Y., Hossain, M.
A,, Tsukamoto, I., Tokuda, M. & Yamaguchi, F.* (2012). Rare sugar d-allose
strongly induces thioredoxin-interacting protein and inhibits osteoclast
differentiation in Raw264 cells. Nutr Res. 32, 116-23.
Yang ZZ, Grote DM, Ziesmer SC, Niki T, Hirashima M, Novak AJ, Witzig TE,
Ansell SM. (2012). IL-12 upregulates TIM-3 expression and induces T cell
exhaustion in patients with follicular B cell non-Hodgkin lymphoma. J.
Clin Invest. 122, 1271-1282.
Yoshida H, Teraoka M, Yoshihara A, Izumori K, Kamitori S.* (2011). Overexpression,
crystallization and preliminary X-ray diffraction analysis of L-ribose
isomerase from Acinetobacter sp. strain DL-28. Acta Crystallogr. Sect F
67, 1281-1284.
Zhou Q, Munger ME, Veenstra RG, Weigel BJ, Hirashima M, Munn DH, Murphy
WJ, Azuma M, Anderson AC, Kuchroo VK, Blazar BR. (2011). Coexpression of
Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with
disseminated acute myelogenous leukemia. Blood,117, 4501-4510.
○N. Nagase，K. Shimizu, N. Uchiyama, K. Tamai, K. Terao, T. Suzuki, F. Oohira：Surface
Plasmon Resonance Sensing by Electrodeposited Au Nanostructures for Sensitivity
Enhancement, The 6TH International Conference on Microtechnologies in Medicine
and Biology，2011/5/4～5/6, Lucerne ,Switzerland
○Yoshida, H., Teraoka, M., Yoshihara, A., Izumori, K. & Kamitori, S.
Crystal structure of a rare sugar producible enzyme L-ribose isomerase
from Acinetobacter sp. 36th FEBS Congress, June 2011, Torino, Italy.
○N. Miyanishi, A. Hoshinoo, N. Nishi, S. Nakakita, J. Hirabayashi, S. Kamitori: What
is real target of galectin-3?, XXI International Symposium on Glycoconjugate
(GLYCO21), 2011/8/21-26, Vienna, Austria.
○N. Nagase, K. Shimizu, N. Miyanishi, S. Shimamoto, K. Terao, T. Suzuki,
F. Oohira: Size-Exclusion Surface Plasmon Resonance Sensing with a Microslit
Array Chip, The ASME-JSME-KSME Joint Fluids Engineering Conference 2011
(AJK2011-FED), 2011/7/24-29, Hamamatsu, Japan.
○Fujiwara, K., Fukada, K., and Izumori, K.: Mixed sugar crystallization
from solution phase. Rare Sugar Congress in Kagawa 2011, 高松, 2011年11月
○Fukada, K., Ogawa, T., Fukada, H., Oshima, H. and Izumori, K.: Basic solution
properties of ketohexoses. Rare Sugar Congress in Kagawa 2011, 高松, 2011年11月
○Ishii, T., Yasuhiro Tahara, Akifumi Yamauchi, Shizuka Kayahara, Shunsuke
Ohga, Kazuhiro Fukada, Kenji Morimoto, Ken Izumori, Shigehiro Kamitori,
and Hiromi Yoshida, "Crystal Structures and Electronic Structures
of Rare Sugar Molecules and Supermolecules", The 5th Symposium of
International Society of Rare Sugar (Rare Sugar Congress 2011), Kagawa,
Japan. (9/Nov./2011)
○Kayahara, S. Tomohiko Ishii, Akihide Yoshihara, Ken Izumori, George W.
J. Fleet, Hiromi Yoshida, and Shigehiro Kamitori, "X-Ray Structure
of 1-Deoxy-1-Fluoro-L-Tagatose", The 5th Symposium of International
Society of Rare Sugar (Rare Sugar Congress 2011), Kagawa, Japan. (11/Nov./2011)
○Kozakai, T., Fukada, K., and Izumori, K.: Co-crystallization of D-psicose
and D-allose mixture. Rare Sugar Congress in Kagawa 2011, 高松, 2011年11月
○Kuroda, T., Wakabayashi, T., Yoshihara, A., Morimoto, K., Fleet, G.W.J.,
Izumori, K.: D-Tagatose 3-epimerase is active on ketotetroses. Rare Sugar
Congress 2011 in Kagawa, International Society of Rare Sugar, Kagawa, 63.
(2011).
○Hamamae, N., Hayakawa, S., Ogawa. M.: Effect of D-psicose on the quality
of bakery foods, Rare Sugar Congress 2011 in Kagawa, International Society
of Rare Sugars, p.90, 高松, 2011年11月
○Hayakawa, S., Ogawa. M.: D-Psicose may replace sucrose for improving the
quality of food products, Rare Sugar Congress 2011 in Kagawa, International
Society of Rare Sugars, p.44, 高松, 2011年11月
○Lumyong, S., Siangsuepchart, A., Yoshihara, A., Morimoto, K., Izumori,
K.: Production of D-lyxose from D-xylose by enzymatic and microbial reaction.
Rare Sugar Congress 2011 in Kagawa, International Society of Rare Sugar,
Kagawa, 26. (2011).
○Mogami, K., Yoshihara, A., Kenji Morimoto, K., Fleet, G.W.J., Ken Izumori,
K.: Production of novel 4-deoxy-pentoses from 2-deoxy-D-ribose. Rare Sugar
Congress 2011 in Kagawa, International Society of Rare Sugar, Kagawa, 67.
(2011).
○Mohammad Akram Hossain*, Yuko Hirata, Kazuyo Kamitori, Youyi Dong, Fuminori
Yamaguchi, Koji Murao, Akira Nishiyama, Ikuko Tsukamoto, Yukiyasu Toyoda,
Tetsuo Iida, Masaaki Tokuda: D-psicose supplementation modulates glucose
homeostasis and pancreas islet function in type 2 diabetes model, OLETF
rats. The 5th Symposium of International Society of Rare Sugars, 高松, 2011年11月
○Momoji, A., Yoshihara, A., Morimoto, K., Wormald, M.R., Fleet, G.W.J.,
Best, D., Izumori, K.: Production of novel 5-deoxy-hexose from 2-deoxy-D-glucose.
Rare Sugar Congress 2011 in Kagawa, International Society of Rare Sugar,
Kagawa, 65. (2011).
○Nonogaki, Y., Hayai, Y., Yoshihara, A., Morimoto, K., Kamitori, S., Wormald,
M.R., Fleet, G.W.J., Izumori, K.: D-Xylose isomerase is active on 1-deoxy-3-keto-
D-galactitol. Rare Sugar Congress 2011 in Kagawa, International Society
of Rare Sugar, Kagawa, 62. (2011).
○Okamitsu, M., Fukada, K., and Sato, M.: Relation between spectroscopic
property and molecular structure of ketohexoses in solution. Rare Sugar
Congress in Kagawa 2011, 高松, 2011年11月
○Sato, M., Sakoguchi, H., Ooishi, A., Kinoshita, Y., Fujisawa, T., Sakashita,
K., Izumori, K.: D-Psicose extends Caenorhabditis elegans lifespan by increasing
oxidative stress resistance. Rare Sugar Congress 2011, Kagawa, 36 (2011).
○Shompoosang, S., Morimoto, K., Yoshihara, A., Wormald, M.R., Jenkinson,
S.F., Fleet, G.W.J., Izumori, K.: Production of 6-deoxy-L-altrose and 6-deoxy-L-allose
from L- rhamnose by enzymatic reactions. Rare Sugar Congress 2011 in Kagawa,
International Society of Rare Sugar, Kagawa, 64. (2011).
○Siangsuepchart, A., Yoshihara, A., Izumori, K., Morimoto, K., Lumyong,
S.: D-Lyxose production from D-xylose using D-mannose isomerase and D-xylose
isomerase (sweetzyme). Rare Sugar Congress 2011 in Kagawa, International
Society of Rare Sugar, Kagawa, 69. (2011).
○Terami, Y., Yoshihara, A., Takata, G., Morimoto, K., Izumori K.: Cloning
and characterization of a novel gene encoding L-ribose isomerase from Raoultella
ornithinolytica MB426 in Escherichia coli. Rare Sugar Congress 2011 in
Kagawa, International Society of Rare Sugar, Kagawa, 61. (2011).
○Tokuda, M., Ken Izumori, Kazuhiro Fukada, Shigeru Hayakawa, Mohammad Akram
Hossain, Tetsuo Iida, and Kazuhiro Okuma: How the New frontier of D-psicose
world has been created in Kagawa. The 5th Symposium of International Society
of Rare Sugars, 高松, 2011年11月
○Uechi, K., Yoshihara, A., Morimoto, K., Takata, G., Izumori, K.: Cloning
and characterization of mutant L-ribulose 3-epimerase for production of
rare sugars from Mesorhizobium loti. Rare Sugar Congress 2011 in Kagawa,
International Society of Rare Sugar, Kagawa, 66. (2011).
○Yamaguchi, F., Kana Yamada, Chisato Noguchi, Kazuyo Kamitori, Youyi Dong,
Yuko Hirata, Mohammad A Hossain, Ikuko Tsukamoto, Masaaki Tokuda: Rare
sugar D-allose strongly induces thioredoxin interacting protein (TXNIP)
and inhibits osteoclast differentiation in Raw264 cells. The 5th Symposium
of International Society of Rare Sugars, 高松, 2011年11月
○Yamauchi, A., Kayahara, S., Ohga, S., Ishii, T., Fukada, K., Morimoto,
K., Izumori, K., Sato, M., and Sakane, G.: Powder pattern X-ray crystal
structural analysis of b-D-gulose. Rare Sugar Congress in Kagawa 2011,
高松, 2011年11月
○Yanagita, RC, N. Hashitani, and Y.Kawanami, Role of Polar Functional Group
of 6-O-Acyl-D-allose on the Plant Growth-Inhibitory Effect, The 5th Symposium
of International Society of Rare Sugars, Rare Sugar Congress 2011 in Kagawa,
P52 (2011)
○Yoshida, H., Yamada, M., Takeda, K., Nishitani, T., Ohyama, Y., Yamaji,
M., Ishii, T., Takada, G., Izumori, K. & Kamitori, S. X-ray structures
of the enzymes used for rare sugar production and their catalytic reaction
mechanisms. Rare Sugar Congress, November 2011, Takamatsu, Japan.
○Yoshida, H., Teraoka, M., Izumori, K. & Kamitori, S. Structure analysis
of mutant L-rhamnose isomerase from Pseudomonas stutzeri to elucidate the
ring opening mechanism. Rare Sugar Congress, November 2011, Takamatsu,
Japan.
Tsukamoto, Y. Kawanami, Y. Kubota, and R. Konishi, The Effect of Rare sugar
Fatty A cid Esters on the Tube Formation of HUVEC, Proceedings of the Fourth
Symposium of International Society of Rare Sugars, 159-164 (2011)
G. Afach, M. Ueda, C. Kataoka, and Kawanami, The Effect of D-Psicose Fatty
Acid Esters on Plant Growth, Proceedings of the Fourth Symposium of International
Society of Rare Sugars, 171-176 (2011)
Glycoscience Protocol Online Database (GlycoPOD) (http://jcggdb.jp/GlycoPOD/protocolListShow.action) "Expression
and purification of recombinant human galectin-9", Nishi N and Nakamura
T，"Assay method for the antiproliferative activity of human galectin-9",
Nishi N and Nakamura T
平成22年度 研究成果の発表
原著論文(査読あり）
Arikawa T, Saita N, Oomizu S, Ueno M, Matsukawa A, Katoh S, Kojima K, Nagahara
K, Miyake M, Yamauchi A, Kohrogi H, & Hirashima M*. (2010) Galectin-9
expands immunosuppressive macrophages to ameliorate T cell-mediated lung
inflammation. Eur J Immunol, 40(2): 548-558.
Chagan-Yasutan H, Shiratori B, Siddiqi UR, Saitoh H, Ashino Y, Arikawa
T, Hirashima M, Hattori T*. (2010) The increase of plasma galectin-9 in
a patient with insulin allergy: a case report. Clin Mol Allergy,8: 12 (1-4).
Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, Lee DH, Cornejo
M, Nishi N, Yamauchi A, Quintana FJ, Sobel RA, Hirashima M & Kuchroo
VK*. (2010) Tim-3/galectin-9 pathway: regulation of Th1 immunity through
promotion of CD11b+Ly-6G+ myeloid cells. J. Immunol.,185: 1383-1392.
Gullapalli P, Yoshihara A, Morimoto K, Rao D, Akimitsu K, Jenkinson S.F,
Fleet W. J.G. & Izumori K. Conversion of L-rhamnose into ten of the
sixteen 1- and 6-deoxyketohexoses in water with three reagents: D-tagatose-3-epimerase
equilibrates C3 epimers of deoxyketoses. (2010) Tetrahedron Letters, 51(6),
895-898.
Fukada K,* Ishii T, Tanaka K, Yamaji M, Yamaoka Y, Kobashi K, & Izumori
K. (2010) Crystal Structure, Solubility, and Mutarotation of the Rare Monosaccharide
D-Psicose. Bull. Chem. Soc. Jpn., 83(10), 1193-1197.
Hasehira K, Nakakita S, Miyanishi N, Sumiyoshi W, Hayashi S, Takegawa K.
& Hirabayashi J. (2010) A comprehensive HPLC analytical system for
the identification and quantification of hexoses that employs 2-aminobenzamide
coupling. J Biochem. 147(4):501-9.
Horlacher T, Oberli MA, Werz DB, Krock LH, Bufali S, Stocker B, Mishra
R, Sobek J, Simons K, Hirashima M, Niki T. & Seeberger PH*. (2010)
Determination of carbohydrate-binding preferences of human galectins with
carbohydrate microarrays., ChemBioChem,11 (11): 1563-1573.
Ikeda S.*, Gohtani S., Fukada K., Amo Y. (2010) Dielectric relaxation and
water activity in aqueous solution of D-psicose. Submitted to Jpn. J. Food
Eng..
Iqbal AJ, Sampaio ALF, Maione F, Greco KV, Niki T, Hirashima M, Cooper
D*, & Perretti M.* (2011) Endogenous galectin-1 in a murine model of
paw edema: emerging notion of galectin-9 pro-resolving effect. Am. J. Pathol.,in
press.
Kadowaki T, Inagawa H, Kohchi C, Hirashima M & Soma G*. (2010) Preparation
of lipopolysaccharide derived from Pantoea agglomerans labeled with fluorescence
as a tracer for kinetics analysis. Anticancer Res,30(8): 3151-3157.
Katoh S*, Nobumoto A, Matsumoto N, Matsumoto K, Ehara N, Niki T, Inada
H, Nishi N, Yamauchi A, Fukushima K & Hirashima M. (2010) Involvement
of galectin-9 in lung eosinophilia in patients with eosinophilic pneumonia.
Int. Arch. Allergy Immunol.,153(3): 294-302.
Kobayashi T, Kuroda J*, Ashihara E, Oomizu S, Terui Y, Taniyama A, Adachi
S, Takagi T, Yamamoto M, Sasaki N, Horiike S, Hatake K, Yamauchi A, Hirashima
M. & Taniwaki M (2010) Galectin-9 exhibits anti-myeloma activity through
JNK and p38 MAP kinase pathways. Leukemia,24 (4): 843-850.
Kobayashi M., Ueda M., Furumoto T. & Kawanami Y* (2010) Retardant activity
of 6-O-acyl-D-alloses on plant growth, Bioscience Biotechnology Biochemistry,
73, pp 216-217.
Kuroda J*, Yamamoto M, Nagoshi H, Kobayashi T, Sasaki N, Shimura Y, Horiike
S, Kimura S, Yamauchi A, Hirashima M, & Taniwaki M. (2010) Targeting
activating transcription factor 3 by galectin-9 induces apoptosis and overcomes
various types of treatment resistance in chronic myelogenous leukemia.
Molecular Cancer Research,8 (7): 994-1001.
Mengshol JA, Golden-Mason L, Arikawa T, Smithv M, Niki T, McWilliams R,
Randall J, McMahan R, Rangachari M, Dobrinskikh E, Busson P, Polyak SJ,
Hirashima M & Rosen HR*. (2010) A crucial role for Kupffer cell-derived
galectin-9 in regulation of T cell immunity in chronic hepatitis C infection.
Plos One,5(3): e9504.
Mishra R, Grzybek M, Niki T, Hirashima M & Simons K*. (2010) Galectin-9
trafficking regulates apical-basal polarity in Madin-Darby canine kidney
epithelial cells. PNAS,107 (41): 17633-17638.
Manabe S., Nariya H., Miyata S., Tanaka H., Minami J., Suzuki M., Taniguchi
Y. & Okabe A.* (2010). Purification and characterization of a clostripain-like
protease from a recombinant Clostridium perfringens culture. Microbiology,
156, 561-569.
Miyanaka H., Nakamura T. & Nishi N.* (2010) Tissue-specific expression
of fucosylated glycosphingolipid species in rat prostate. Biosci. Biotechnol.
Biochem., 74, 1261-1266.
Miyanishi N, Nakakita S, Sumiyoshi W, Okuma H, Izumori K, Hirabayashi J.
(2010) Development of D-allose sensor on the basis of three strategic enzyme
reactions. Biosens Bioelectron. 26(1):126-30.
Nariya, H.*, Miyata, S., Suzuki, M., Tamai, E. & Okabe, A. (2011).
Development and application of a method for counterselectable in-frame
deletion in Clostridium perfringens. Appl. Environ. Microbiol. in press.
Natsuka, S.*, Hirohara, Y., Nakakita, S., Sumiyoshi, W. & Hase, S.
(2010). Structural analysis of N-glycans of the planarian Dugesia japonica.
FEBS J. in press.
Ohashi, T., Nakakita, S., Sumiyoshi, W., Yamada, N., Ikeda, Y., Tanaka,
N. & Takegawa, K.* (2010). Structural analysis of a1,3-linked galactose-containing
oligosaccharides in Schizosaccharomyces pombe mutants harboring single
and multiple a-galactosyltransferase genes disruptions. Glycobiology in
press.
Ohashi, T., Nakakita, S., Sumiyoshi W. & Takegawa K.* (2010). Production
of heterologous glycoproteins by a glycosylation-defective alg3och1 mutant
of Schizosaccharomyces pombe J. Biotechnol. 150, 348-156.
Rao D, Best D, Yoshihara A, Gullapalli P, Morimoto K, Wormald MR, Wilson
FX, Izumori K, & Fleet WJ. G. (2009) A concise approach to the synthesis
of all twelve 5-deoxyhexoses: D-tagatose-3-epimerase—a reagent that is
both specific and general. Tetrahedron Letters, 50(26), 3559-3563.
Sakai K, Kawata E, Ashihara E*, Nakagawa Y, Yamauchi A, Yao H, Nagao R,
Tanaka R, Yokota A, Takeuchi M, Hirai H, Kimura S, Hirashima M, Yoshimura
N & Maekawa T. (2011) Galectin-9 ameliorates acute GVH disease through
the induction of T-cell apoptosis. Eur J Immunol,41(1): 67-75.
Sato, M. *, Toyazaki, H., Yoshioka, Y., Yokoi, N. & Yamasaki, T. (2010)
Structural characteristics for superoxide anion radical scavenging and
productive activities of green tea polyphenols including proanthocyanidin
dimers. Chemical and Pharmaceutical Bulletin 58, 98-102.
Sehrawat S, Reddy PBJ, Rajasagi N, Suryawanshi A, Hirashima M & Rouse
BT*. (2010) Galectin-9/TIM-3 interaction regulates virus-specific primary
and memory CD8+ T cell response. PLOS Pathogens,6 (5): e1000882.
Sumiyoshi W, Nakakita S, Hasehira K, Miyanishi N, Kubo Y, Kita T &
Hirabayashi J. Comprehensive analysis of N-linked oligosaccharides from
eggs of the family Phasianidae. Biosci Biotechnol Biochem. 2010;74(3):606-13.
Suzuki, S., Matsuzawa, T., Nukigi, Y., Takegawa, K. & Tanaka, N. (2010)
Characterization of two different types of UDP-glucose/-galactose 4-epimerase
involved in galactosylation in fission yeast. Microbiology 156, 708-718
Takeda K., Yoshida H., Izumori K. & Kamitori S.* (2010). X-ray structures
of Bacillus pallidus D-arabinose isomerase and its complex with L-fucitol.
BBA - Proteins and Proteomics, 1804, 1359-1368.
Tanaka H., Nariya H., Suzuki M., Houchi H., Tamai E., Miyata S.* &
Okabe A. (2011) High-level production and purification of clostripain expressed
in a virulence-attenuated strain of Clostridium perfringens. Protein Expr.
Purif., 76, 83-89.
Tanikawa R, Tanikawa T, Hirashima M, Yamauchi A, Tanaka Y*. (2010) Galectin-9
induces osteoblast differentiaion through the CD44/Smad signaling pathway.
BBRC,394(2): 317-322.
Yoshida H., Teraoka M., Nishi N., Nakakita S., Nakamura T., Hirashima M.
& Kamitori S.* (2010). X-ray structures of human galectin-9 C-terminal
domain in complexes with a biantennary oligosaccharide and sialyllactose.
J. Biol. Chem., 285, 36969-36976.
Yoshida H., Takeda K., Izumori K. & Kamitori S.* (2010) Elucidation
of the role of Ser329 and the C-terminal region in the catalytic activity
of Pseudomonas stutzeri L-rhamnose isomerase. Protein Eng. Des. Sel., 23,
919-927.
Vega-Carrascal I,Reeves EP*, Niki T, Arikawa T, McNally P, O’Neill SJ,
Hirashima M. & McElvaney NG. (2011) Dysregulation of TIM-3/Galectin-9
pathway in the cystic fibrosis airways. J. Immunol.,in press.
Zhou Q, Meghan E. Munger ME, Veenstra RG, Hirashima M, Munn DH, Murphy
WJ, Azuma M, Anderson AC, Kuchroo VK, & Blazar BR*. (2011) Co-expression
of T-Cell Immunoglobulin and Mucin 3 Protein (Tim-3) and Program Death-1
(PD-1) Identifies a T-Cell Exhaustion Phenotype in Mice with Disseminated
Acute Myelogenous Leukemia. Blood, in press.
Hirashima M. Galectin-9 beneficially modulates macrophage functions in
inflammation and cancer. 18th International Symposium on Molecular Cell
Biology of Macrophages. 2010 5.20-21, Kumamoto.
Hirashima M. Galectin-9 in autoimmune pancreatitis and pancreatic cancer.
18th Yonsei International Gastroenterology Symposium. 2010.12.4, Seoul,
Korea.
○Kazuhiro Fukada, Harumi Fukada, Ken Izumori, Thermodynamic Properties
of Hexoses in Aqueous Solution. 21st IUPAC International Conference on
Chemical Thermodynamics ICCT-2010 , つくば, 2010年6月.
○Yoshida, H., Teraoka, M., Nishi, N., Nakamura, T., Hirashima, M. &
Kamitori, S. (2010). Crystal structure of the C-terminal carbohydrate recognition
domain of human galectin-9. 35th FEBS Congress, June 2010, Gothenburg,
Sweden.
Yoshida, H., Teraoka, M., Nishi, N., Nakakita, S., Nakamura, T., Hirashima,
M. & ○Kamitori, S. (2010). X-ray Structure of Galectin-9 C-terminal
Domain in Complex with N-linked Oligosaccharide with a Branch. The 25th
International Carbohydrate Symposium, Aug. 2010, Tokyo－Chiba, Japan.
○Yoshida, H., Takeda, K., Tahara, Y., Ishii, T., Izumori, K. & Kamitori,
S. (2010). X-ray structures of rare sugar production related enzymes and
the catalytic mechanisms. The 25th International Carbohydrate Symposium,
Aug. 2010, Tokyo－Chiba, Japan.
Hasehira K, ○Nakakita S, Miyanishi N, Sumiyoshi W, Hayashi S, Takegawa
K, Hirabayashi, J. (2010). Comprehensive HPLC Analytical System for the
Identification and Quantification of Hexoses that Employs 2-aminobenzamide
coupling. The 25th International Carbohydrate Symposium, Aug. 2010, Tokyo-Chiba,
Japan
○I. Tsukamoto, Y. Kawanami, Y. Kubota, M. Tokuda, R. Konishi, K. Osumi,
Y. Hirose, M. Fujita, M. Mizuno, The Effects of Esterification of Monosaccharide on
the Inhibitory Potency for Angiogenesis, The 25th Carbohydrate Symposium
(ICS2010), 東京、2010年 8月
○Yasuhiro Tahara, Tomohiko Ishii, Masatsugu Yamaji, Yuji Watanabe, Kei
Takeshita, Shigehiro Kamitori, Hiromi Yoshida, and Ken Izumori, "X-Ray
Structure Analyses and Electronic Structure of Rare Sugars", The 6th
International Conference on DV-Xα Method, Daejeon, Korea Aug. 2010.
○Akifumi Yamauchi, Shizuka Kayahara, Yasuhiro Tahara, Tomohiko Ishii, Genta
Sakane, Kazuhiro Fukada, and Ken Izumori, "Crystal Structure and Electronic
Structure of Rare Sugar Superlattice", The 6th International Conference
on DV-Xα Method, Daejeon, Korea Aug. 2010.
○Oomizu S, Arikawa T, Niki T, Yamauchi A, Hirashima M. Galectin-9 down-regulates
Th17 cell differentiation independently of Tim-3/Galectin-9 interaction.
第14回国際免疫学会議、2010.8.23、神戸
○Morimoto K, Miyake S, Yoshihara A, Takata G, Izumori K.: D- glucoside
3-dehydrogenase (G3DH) from Agrobacterium tumefaciens M31. 3rd Joint between
Chiang Mai University- Kagawa University Academic Symposium. 129. (Aug.
2010)
○Takechi N, Morimoto K, Yoshihara A, Takata G, Izumori, K.: Production
of new disaccharides contained rare sugar D-allose. 3rd Joint between Chiang
Mai University- Kagawa University Academic Symposium. 136. (Aug. 2010)
○Tokuda M, Hossain M. A., Tsukamoto I., Nishiyama, A., Murao, K. Dong,
Y., Yamaguchi, F., Kamitori, K. Hirata, Y. Wise usage of functional foods:
Rare sugars, the new bio-materials for healthy society. The 3rd Joint Symposium
between Chiang Mai University and Kagawa University (Aug. 2010).
○Fukada K., Furuta Y., Kawanami Y, Interfacial Properties of Regioselectiely
Acylated Sugar-based Surfactants. International Conference on Nanoscopic
Colloid and Surface Science NCSS2010, 1PA02, 東京、2010年9月．
○Tahara, Y., Ishii, T., Yoshida, H., Izumori, K. & Kamitori, S. (2010). Crystal
Structure of D-tagatose 3-Epimerase Cys66Ser from Pseudomonas cichorii.
2010 International Chemical Congress of Pacific Basin Societies, Dec. 2010,
Honolulu, Hawaii, U.S.A.
○Kazuhiro Fukada, Masakazu Okamitsu, Relation between molecular structure
and solution property of monosaccharides: solubility, viscosity, and compressibility
of ketohexoses in aqueous solution. 2010年環太平洋国際化学会議：2010 International
Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, USA, 2010年.
○Yamasaki, T., Sato, M., D-Psicose inhibits the growth of L1 stage Caenorhabditis
elegans: A possible inhibition mechanism.3rd International Conference on
Drug Discovery and Therapy, Feb. 2011, Dubai, U.A.E.
○O’Charoen Siwaporn, Hayakawa Shigeru, Ogawa Masahiro, Functional Improvement
of Egg White Protein by Rare Ketohexoses,日本農芸化学会2011年度大会，京都（2011.3).