@y@‹Æ@Ñ@z

2015

Nonaka Y, Ogawa T, Yoshida H, Shoji H, Nishi N, Kamitori S, Nakamura T. Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-1. Glycobiology, 2015;25(7),792-803.


2014


Fukata Y, Itoh A, Nonaka Y, Ogawa T, Nakamura T, Matsushita O, Nishi N. Direct cytocidal effect of galectin-9 localized on collagen matrices on human immune cell lines. Biochim Biophys Acta. 2014; 1840(6), 1892-1901
Arikawa T, Simamura E, Shimada H, Nakamura T, Hatta T, Shoji H. * (2014) Significance of sugar chain recognition by galectins and its involvement in disease-associated glycosylation. ?Congenit. Anom.(Kyoto) In press.


2013

Nonaka Y, Ogawa T, Oomizu S, Nakakita S, Nishi N, Kamitori S, Hirashima M, Nakamura T.
Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site. J Biochem. 2013; 153(5), 463-471.

Itoh A, Fukata Y, Miyanaka H, Nonaka Y, Ogawa T, Nakamura T, Nishi N. Optimization of the inter-domain structure of galectin-9 for recombinant production. Glycobiology. 2013; 23, 920-925.
Sato H, Oyanagi J, Komiya E, Ogawa T, Higashi S, Miyazaki K.
Amino-terminal fragments of laminin ƒÁ2 chain retract vascular endothelial cells and increase vascular permeability.
Cancer Sci. 2013 Nov 15. doi: 10.1111/cas.12323.
Kamoshida G, Ogawa T, Oyanagi J, Sato H, Komiya E, Higashi S, Miyazaki K, Tsuji T.Modulation of matrix metalloproteinase-9 secretion from tumor-associated macrophage-like cells by proteolytically processed laminin-332 (laminin-5).
Clin Exp Metastasis. 2013 Dec 1.


2012

Arikawa T, Simamura E, Shimada H, Nishi N, Tatsuno T, Ishigaki Y, Tomosugi N, Yamashiro C, Hata T, Takegami T, Mogami H, Yamaguchi K, Nakamura T, Otani H, Hatta T, Shoji H.
Expression pattern of Galectin 4 in rat placentation.
Placenta. 2012 Oct;33(10):885-7. doi: 10.1016


2011

Iwaki J, Tateno H, Nishi N, Minamisawa T, Nakamura-Tsuruta S, Itakura Y, Kominami J, Urashima T, Nakamura T, Hirabayashi J.
The Gal
ƒÀ-(syn)-gauche configuration is required for galectin- recognition disaccharides.
Biochim Biophys Acta. 1810(7): 643-51. (2011)


2010

Yoshida H, Teraoka M, Nishi N, Nakakita SI, Nakamura T, Hirashima M, Kamitori S.
X-ray structures of human galectin-9 C-terminal domain in complexes with a biantennary oligosaccharide and sialyllactose.
J Biol Chem, 285(47):36969-76. (2010)


Miyanaka H, Nakamura T, Nishi N.
Tissue-specific expression of fucosylated glycosphingolipid species in rat prostate.

Biosci Biotechnol Biochem,23;74(6):1261-6. (2010)


2009


H. Shoji, L. Deltour, T. Nakamura, S. Tajbakhsh & F. Poirier.
Expression pattern and role of galectin-1 during early mouse myogenesis. Dev.Growth.Differ. (2009), 51,607-615:

H. Nagae, N. Nishi, T. Murata, T. Usui, T. Nakamura, S. Wakatsuki & R. Kato
Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. Glycobiology (2009), 19,112-117:


2008

Nagae M, Nishi N, Murata T, Usui T, Nakamura T, Wakatsuki S, Kato R. Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. Glycobiology. (2009) 19(2):112-117.

Nishi N, Abe A, Iwaki J, Yoshida H, Itoh A, Shoji H, Kamitori S, Hirabayashi J, Nakamura T. Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1. Glycobiology. (2008) 18(12):1065-1073.

Iwaki J, Minamisawa T, Tateno H, Kominami J, Suzuki K, Nishi N, Nakamura T, Hirabayashi J. Desulfated galactosaminoglycans are potential ligands for galectins: evidence from frontal affinity chromatography. Biochem Biophys Res Commun. (2008) 373(2):206-212.

Nishi N, Shoji H, Miyanaka H, Nakamura T. Transient up-regulation of a novel member of Spot 14 family in androgen-stimulated rat prostate. Biochim Biophys Acta. (2008) 1780(7-8):1004-9.

Yamamoto H, Nishi N, Shoji H, Itoh A, Lu LH, Hirashima M, Nakamura T. Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T-cells. J Biochem. (2008) 143(3):311-24.

’†‘º@—²”ÍA¼@–]A“ŒŠC—Ñ@”ŽŽ÷@uƒKƒŒƒNƒ`ƒ“‚ƖƉu’²ßv@—Õ°ŒŸ¸(2008) 52(8)871-879.


2007

Yamamoto H, Kashio Y, Shoji H, Shinonaga R, Yoshimura T, Nishi N, Nabe T, Nakamura T, Kohno S, Hirashima M. Involvement of galectin-9 in guinea pig allergic airway inflammation. Int Arch Allergy Immunol. (2007) 143 :95-105.

Tsuboi Y, Abe H, Nakagawa R, Oomizu S, Watanabe K, Nishi N, Nakamura T, Yamauchi A, Hirashima M. Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes. Clin Immunol. (2007) 124(2):221-33.

Miyanishi N, Nishi N, Abe H, Kashio Y, Shinonaga R, Nakakita S, Sumiyoshi W, Yamauchi A, Nakamura T, Hirashima M, Hirabayashi J. Carbohydrate-recognition domains of galectin-9 are involved in intermolecular interaction with galectin-9 itself and other members of the galectin family. Glycobiology. (2007) 17(4):423-32.

Lu LH, Nakagawa R, Kashio Y, Ito A, Shoji H, Nishi N, Hirashima M, Yamauchi A, Nakamura T. Characterization of galectin-9-induced death of Jurkat T cells. J Biochem. (2007) 141(2):157-72.

Imaizumi T, Yoshida H, Nishi N, Sashinami H, Nakamura T, Hirashima M, Ohyama C, Itoh K, Satoh K.Double-stranded RNA induces galectin-9 in vascular endothelial cells: involvement of TLR3, PI3K, and IRF3 pathway.Glycobiology. (2007) 17(7):12C-5C.


2006

Nishi N, Itoh A, Shoji H, Miyanaka H, Nakamura T. Galectin-8 and galectin-9 are novel substrates for thrombin. Glycobiology. (2006) 16(11):15C-20C.

Nagae M, Nishi N, Murata T, Usui T, Nakamura T, Wakatsuki S, Kato R.Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.J Biol Chem. (2006 )281(47):35884-35893.


2005

Irie, A., Yamauchi, A., Kontani, K., Kihara, M., Liu, D., Shirato, Y., Seki, M., Nishi, N., Nakamura, T., Yokomise, H., and Hirashima, M. (2005) Galectin-9 as a prognostic factor with antimetastatic potential in breast cancer. Clin. Cancer Res. 11, 2962-2968.

Nishi, N., Itoh, A., Fujiyama, A., Yoshida, N., Araya, S., Hirashima, M., Shoji, H., and Nakamura, T. (2005) Development of highly stable galectins: Truncation of the linker peptide confers protease-resistance on tandem-repeat type galectins. FEBS Lett. 579, 2058-2064.

Pioche-Durieu, C., Keryer, C., Souquere, S., Bosq, J., Faigle, W., Loew, D., Hirashima, M., Nishi, N., Middeldorp, J., and Busson, P. (2005) In nasopharyngeal carcinoma cells, Epstein-Barr virus LMP1 interacts with galectin 9 in membrane raft elements resistant to simvastatin. J. Virol. 79, 13326-13337.

Sakaki, H., Imaizumi, T., Matsumiya, T., Kusumi, A., Nakagawa, H., Kubota, K., Nishi, N., Nakamura, T., Hirashima, M., Satoh, K., and Kimura, H. (2005) Retinoic acid-inducible gene-I is induced by interleukin-1beta in cultured human gingival fibroblasts. Oral. Microbiol. Immunol. 20, 47-50.

Shoji, H., Ikenaka, K., Nakakita, S., Hayama, K., Hirabayashi, J., Arata, Y., Kasai, K., Nishi, N., and Nakamura, T. (2005) Xenopus galectin-VIIa binds N-glycans of members of the cortical granule lectin family (xCGL and xCGL2). Glycobiology 15, 709-720.

Toyoshima, T., Nishi, N., Kusama, H., Kobayashi, R., and Itano, T. (2005) 36-kDa microfibril-associated glycoprotein (MAGP-36) is an elastin-binding protein increased in chick aortae during development and growth. Exp. Cell Res. 307, 224-230.

Dai S.-Y., Nakagawa R., Itoh A., Murakami H., Kashio Y., Abe H., Katoh S., Kontani K., Kihara M., Zhang S.-L., Hata T., Nakamura T., Yamauchi A. & Hirashima M.(2005).
Galectin-9 induces maturation of human monocyte-derived dendric cells. J. Immunol. 175: 2974-2981.

’†‘º—²”ÍA¼@–] (2005) ƒKƒŒƒNƒ`ƒ“‚Ì•W“I•ªŽq‚ð‘{‚¹@¶‰»Šw@77, 1509-1513


2004

Ishida, T., Hatae, T., Nishi, N., Araki, N., and Hamasaki, M. (2004)@Immunocytochemical analysis of cubilin-mediated endocytosis of high density lipoproteins (HDL) in epithelial cells of the rat visceral yolk sac. Cell Tissue Res. 318, 533-543.

Ishikawa, A., Imaizumi, T., Yoshida, H., Nishi, N., Nakamura, T., Hirashima, M., and Satoh, K. (2004) Double-stranded RNA enhances the expression of galectin-9 in vascular endothelial cells. Immunol. Cell Biol. 82, 410-414.

Hirashima, M., Kashio, Y., Nishi, N., Yamauchi, A., Imaizumi, T., Kageshita, T., Saita, N., and Nakamura, T. (2004) Galectin-9 in physiological and pathological conditions. Glycoconj. J. 19, 593-600.


2003

Imaizumi, T., Kumagai, M., Nishi, N., Hirashima, M., Hatakeyama, M., Tamo, W., Yoshida, H., Nakamura, T., Okumura, K., and Satoh, K. (2003)@15-Deoxy-Delta(12,14)-Prostaglandin J(2) Inhibits IFN-gamma-Induced Galectin-9 Expression in Cultured Human Umbilical Vein Endothelial Cells. Int. Arch. Allergy Immunol. 131, 57-61.

Kashio, Y., Nakamura, K., Abedin, M. J., Seki, M., Nishi, N., Yoshida, N., Nakamura, T., and Hirashima, M. (2003) Galectin-9 induces apoptosis through the calcium-calpain-caspase-1 pathway. J. Immunol. 170, 3631-3636.

Nishi, N., Shoji, H., Seki, M., Itoh, A., Miyanaka, H., Yuube, K., Hirashima, M., and Nakamura, T. (2003) Galectin-8 modulates neutrophil function via interaction with integrin alphaM. Glycobiology 13, 755-763.

Pelletier, I., Hashidate, T., Urashima, T., Nishi, N., Nakamura, T., Futai, M., Arata, Y., Kasai, K., Hirashima, M., Hirabayashi, J., and Sato, S. (2003) Specific recognition of Leishmania major poly-beta-galactosyl epitopes by galectin-9: possible implication of galectin-9 in interaction between L. major and host cells. J. Biol. Chem. 278, 22223-22230.

Shoji, H., Nishi, N., Hirashima, M., and Nakamura, T. (2003) Characterization of the Xenopus galectin family. Three structurally different types as in mammals and regulated expression during embryogenesis. J. Biol. Chem. 278, 12285-12293.


2002

Asakura, H., Kashio, Y., Nakamura, K., Seki, M., Dai, S., Shirato, Y., Abedin, M. J., Yoshida, N., Nishi, N., Imaizumi, T., Saita, N., Toyama, Y., Takashima, H., Nakamura, T., Ohkawa, M., and Hirashima, M. (2002) Selective Eosinophil Adhesion to Fibroblast Via IFN-gamma-Induced Galectin-9. J. Immunol. 169, 5912-5918.

Chabot, S., Kashio, Y., Seki, M., Shirato, Y., Nakamura, K., Nishi, N., Nakamura, T., Matsumoto, R., and Hirashima, M. (2002) Regulation of galectin-9 expression and release in Jurkat T cell line cells. Glycobiology 12, 111-118.

Imaizumi, T., Kumagai, M., Sasaki, N., Kurotaki, H., Mori, F., Seki, M., Nishi, N., Fujimoto, K., Tanji, K., Shibata, T., Tamo, W., Matsumiya, T., Yoshida, H., Cui, X. F., Takanashi, S., Hanada, K., Okumura, K., Yagihashi, S., Wakabayashi, K., Nakamura, T., Hirashima, M., and Satoh, K. (2002) Interferon-gamma stimulates the expression of galectin-9 in cultured human endothelial cells. J. Leukoc. Biol. 72, 486-491.

Kageshita, T., Kashio, Y., Yamauchi, A., Seki, M., Abedin, M. J., Nishi, N., Shoji, H., Nakamura, T., Ono, T., and Hirashima, M. (2002) Possible role of galectin-9 in cell aggregation and apoptosis of human melanoma cell lines and its clinical significance. Int. J. Cancer 99, 809-816.

Sato, M., Nishi, N., Shoji, H., Kumagai, M., Imaizumi, T., Hata, Y., Hirashima, M., Suzuki, S., and Nakamura, T. (2002) Quantification of galectin-7 and its localization in adult mouse tissues. J. Biochem. (Tokyo) 131, 255-260.

Sato, M., Nishi, N., Shoji, H., Seki, M., Hashidate, T., Hirabayashi, J., Kasai, K., Hata, Y., Suzuki, S., Hirashima, M., and Nakamura, T. (2002) Functional analysis of the carbohydrate recognition domains and a linker peptide of galectin-9 as to eosinophil chemoattractant activity. Glycobiology 12, 191-197.

Shoji, H., Nishi, N., Hirashima, M., and Nakamura, T. (2002) Purification and cDNA cloning of Xenopus liver galectins and their expression. Glycobiology 12, 163-172.

Hirabayashi, J., Hashidate, T., Arata, Y., Nishi, N., Nakamura, T., Hirashima, M., Urashima, T., Oka, T., Futai, M., Muller, W., Yagi, F., and Kasai, K. (2002) Oligosaccharide specificity of galectins: a search by frontal affinity chromatography. Biochim. Biophys. Acta 1572, 232-254.


2001

Toyoshima, T., Matsushita, O., Minami, J., Nishi, N., Okabe, A., and Itano, T. (2001) Collagen-binding domain of a Clostridium histolyticum collagenase exhibits a broad substrate spectrum both in vitro and in vivo. Connective Tissue Res. 42, 281-290

Yoshida, H., Imaizumi, T., Kumagai, M., Kimura, K., Satoh, C., Hanada, N., Fujimoto, K., Nishi, N., Tanji, K., Matsumiya, T., Mori, F., Cui, X.-F., Tamo, W., Shibata, T., Takanashi, S., Okumura, K., Nakamura, T., Wakabayashi, K., Hirashima, M., Sato, Y., and Satoh, K. (2001) Interleukin-1b stimulates galectin-9 expression in human astrocytes. Neuroreport 12, 3755-3758.


2000

Shoji H, Tsuchida K, Kishi H, Yamakawa N, Matsuzaki T, Liu Z, Nakamura T, Sugino H.(2000) Identification and characterization of a PDZ protein that interacts with activin type II receptors.J Biol Chem. 275(8):5485--5492.

Matsushita, N., Nishi, N., Seki, M., Matsumoto, R., Kuwabara, I., Liu, F.-T., Hata, Y., Nkamura, T., and Hirashima, M. (2000) Requirement of divalent galactoside-binding activity of ecalectin/galectin-9 for eosinophil chemoattraction. J. Biol. Chem. 275, 8355-8360.

Nishi, N., Shoji, H., Miyanaka, H., and Nakamura, T. (2000) Androgen-regulated expression of a novel member of the aldo-keto reductase superfamily in regrowing rat prostate. Endocrinology 141, 3194-3199.

’†‘º@—²”ÍA¼@–]A“ŒŠC—Ñ@”ŽŽ÷i2000juƒKƒŒƒNƒ`ƒ“ƒtƒ@ƒ~ƒŠ[‚Æ”­¶‚¨‚æ‚Ѷ‘Ì–hŒäv@¶‘̂̉Ȋw@51(3):228-233

Copyright(C)2010 Department of Endocrinology,All rights reserved.