関係論文

Takebayashi G, Chiba Y, Wakamatsu K, Murakami R, Miyai Y, Matsumoto K, Uemura N, Yanase K, Shirakami G, Ogino Y, Ueno M, E-Cadherin Is Expressed in Epithelial Cells of the Choroid Plexus in Human and Mouse Brains. Current Issues in Molecular biology, 2023;45(10):7813-7826.
Systemically Administered D-allose Inhibits the Tumor Energy Pathway and Exerts Synergistic Effects With Radiation ANTICANCER RESEARCH 44: 1895-1903. Accepted March 22, 2024
Irie K, Ohta KI, Ujihara H, Araki C, Honda K, Suzuki S, Warita K, Otabi H, Kumei H, Nakamura S, Koyano K, Miki T, Kusaka T. An enriched environment ameliorates the reduction of parvalbumin-positive interneurons in the medial prefrontal cortex caused by maternal separation early in life. Front Neurosci. 17:1308368. (2024)
Ohta KI, Araki C, Ujihara H, Iseki K, Suzuki S, Otabi H, Kumei H, Warita K, Kusaka T, Miki T. Maternal separation early in life induces excessive activity of the central amygdala related to abnormal aggression. J Neurochem. 167(6):778-794. (2023)
"S. Kamitori, X-ray structures of Enterobacter cloacae allose-binding protein in complexes with monosaccharides demonstrate its unique recognition mechanism for high affinity to allose. Biochemical and biophysical research communications Vol. 682 (2023) 187-192"
"S.M. Khaledur Rahman, Sumire Sasaki, Toru Uyama, Zahir Hussain, Mohammad Mamun Sikder, Hiroyuki Saiga, Mari Ohmura-Hoshino, Ken-ichi Ohta, Yoshimi Miki, Katsuaki Hoshino, Masaki Ueno, Makoto Murakami, Natsuo Ueda PLAAT1 Deficiency Alleviates High Fat Diet-Induced Hepatic Lipid Accumulation in Mice FASEB Journal, 37, e23032 (2023)"
"Mohammad Mamun Sikder, Toru Uyama, Sumire Sasaki, Katsuhisa Kawai, Nobukazu Araki and Natsuo Ueda PLAAT1 expression triggers fragmentation of mitochondria in an enzyme activity-dependent manner Journal of Biochemistry, 175, 101-113 (2024)"
Kawanabe A*, Takeshita K, Takata M, Fujiwara Y* (2023) “ATP modulates the activity of the voltage-gated proton channel through direct binding interaction." J Physiol, 601(18):4073-4089. doi: 10.1113/JP284175.
Watabe E, Kawanabe A, Kamitori K, Ichihara S, Fujiwara Y. “Sugar binding of sodium-glucose cotransporters analyzed by voltage-clamp fluorometry”, J Biol Chem. 2024 Mar 24;300(5):107215. doi: 10.1016/j.jbc.2024.107215. Online ahead of print. PMID: 38522518
Ito M, Ito H, Miyoshi K, Kanai-Azuma M. Chronic non-discriminatory social defeat stress during the perinatal period induces depressive-like outcomes in female mice. Brain Research, 1825:148734. 2024.

T.Ishikawa,Y.Yasuoka,S.Tokonami,H.Takahashi,H.Suda,Characterization of airborne radon released by domestic showering and the use of a washing machine. Journal of Radioanalytical and Nuclear Chemistry,Vol.279,No3(2010)719-724
Hirano M, Hirano K. Critical role of Rho proteins in myosin light chain di-phosphorylation during early phase of endothelial barrier disruption. Journal of Physiological Sciences
Bacova BS, Andelova K, Sykora M, Egan Benova T, Barancik M, Kurahara LH, Tribulova N: Does Myocardial Atrophy Represent Anti-Arrhythmic Phenotype? Biomedicines 10: 2819, 2022.　総説
Hiraishi K, Kurahara LH, Ishikawa K, Go T, Yokota N, Hu Y, Fujita T, Inoue R, Hirano K:Potential of TRPM7 channel as a novel therapeutic target for pulmonary arterial hypertension. J Smooth Muscl Res 58: 50-62, 2022 総説
Hiraishi K, Zhao F, Kurahara LH*, Li X, Yamashita T, Hashimoto T, Matsuda Y, Sun Z, Zhang H, Hirano K:　Lactulose modulates the structure of gut microbiota and alleviates colitis-associated tumorigenesis.Nutrients 14(3): 649, 2022 *責任著者
T.Ishikawa,Y.Yasuoka,S.Tokonami,H.Takahashi,H.Suda,Characterization of airborne radon released by domestic showering and the use of a washing machine. Journal of Radioanalytical and Nuclear Chemistry,Vol.279,No3(2010)719-724
Nakabayashi R, Fujihara S, Iwama H, Hamaya S, Mizuo T, Hirata M, Fujita K, Kono T, Namima D, Fujita N, Yamana H, Kobayashi K, Kamada H, Morishita A, Kobara H, Ono M, Okano K, Masaki T.Effect of Aspirin on G 0/G 1 Cell Cycle Arrest and microRNA Signatures in Pancreatic Adenocarcinoma Cells.Anticancer Res.42(8): 4037-4048, 2022
Nakahara M, Fujihara S, Iwama H, Takuma K, Oura K, Tadokoro T, Fujita K, Tani J, Morishita A, Kobara H, Himoto T, Masaki T.Effect of Lenvatinib treatment on the cell cycle and microRNA profile in hepatocellular carcinoma cells.Biomed Rep.17(4): 78, 2022
"Satoshi Watanabe, Yuta Nihongaki, Kie Itoh, Toru Uyama, Satoshi Toda, Shigeki Watanabe, and Takanari Inoue. Defunctionalizing intracellular organelles such as mitochondria and peroxisomes with engineered phospholipase A/acyltransferases., Nature Communications, 13, 4413 (2022)"
"S. M. Khaledur Rahman, Zahir Hussain, Katsuya Morito, Naoko Takahashi, Mohammad Mamun Sikder, Tamotsu Tanaka, Ken-ichi Ohta, Masaki Ueno, Hiroo Takahashi, Tohru Yamamoto, Makoto Murakami, Toru Uyama†, and Natsuo Ueda†
†Corresponding author, Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2ε in an ex vivo murine model of brain ischemia., Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1867, 159222 (2022)"
"Satomi Ayaki, Tomohiro Mii, Kosuke Matsuno, Takaaki Tokuyama, Takahito Tokuyama, Takashi Tokuyama, Toru Uyama, and Natsuo Ueda, β-1,4-Galactan suppresses lipid synthesis in sebaceous gland cells via TLR4., Journal of Biochemistry, 173, 85-94 (2023)"
Swanson JA, Araki N.,Roles for 3' Phosphoinositides in Macropinocytosis.,Subcell Biochem.
Yoshihara A, Takamatsu Y, Mochizuki S, Yoshida H, Masui R, Izumori K, Kamitori S. (2023) Structural and biochemical characterizations of Thermus thermophilus HB8 transketolase producing a heptulose. Appl Microbiol Biotechnol. 107, 233-245. doi: 10.1007/s00253-022-12297-z.
"Antitumor Effects of Orally Administered Rare Sugar D-Allose in Bladder Cancer
Int J Mol Sci. 2022 Jun 17;23(12):6771. doi: 10.3390/ijms23126771."
Tanaka H, Ishii N, Koga H, Izumi K, Matsui T, Dainichi T. Linear immunoglobulin A bullous dermatosis complicating ulcerative colitis after a missed abortion. Eur J Dermatol. 2022 Sep 1;32(5):656-658
Rahman SMK, Hussain Z, Morito K, Takahashi N, Sikder MM, Tanaka T, Ohta KI, Ueno M, Takahashi H, Yamamoto T, Murakami M, Uyama T, Ueda N. Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A 2 ε in an ex vivo murine model of brain ischemia. Biochim. Biophys. Acta Mol. Cell Biol. Lipds 1867 (2022) 15922.
Jamal M, Tsukamoto I, Maki T, Takei S, Konishi R, Kinoshita H. COA-Cl Evokes Protective Responses Against H2O2-and 6-OHDA-Induced Toxic Injury in PC12 Cells. Neurotox Res. 40(6), 2061-2071, (2022)
"Intermolecular functional coupling between phosphoinositides and the potassium channel KcsA.Kiya T, Takeshita K, Kawanabe A, Fujiwara Y. J Biol Chem. 2022 Aug;298(8):102257. doi:10.1016/j.jbc.2022.102257. Epub 2022 Jul 15."
"Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels. Rozenberg A, Kaczmarczyk I, Matzov D, Vierock J, Nagata T, Sugiura M, Katayama K, Kawasaki Y, Konno M, Nagasaka Y, Aoyama M, Das I, Pahima E, Church J, Adam S, Borin VA, Chazan A, Augustin S, Wietek J, Dine J, Peleg Y, Kawanabe A, Fujiwara Y, Yizhar O, Sheves M, Schapiro I, Furutani Y, Kandori H, Inoue K, Hegemann P, Béjà O, Shalev-Benami M. Nat Struct Mol Biol. 2022 Jun;29(6):592-603. doi: 10.1038/s41594-022-00783-x. Epub 2022 Jun 16."
Takao, K., Suzuki, M., Miyazaki, R., Miyake, M., Akimitsu, K., and Hoshino, K., Immunomodulatory effects of D-allose on cytokine production by plasmacytoid dendritic cells. Biochem Biophys Res Commun 627, 2022, p130-136
Stephen T Yeung, Thomas A Premeaux, Li Du, Toshiro Niki, Satish K Pillai, Kamal M Khanna, Lishomwa C Ndhlovu. Galectin-9 protects humanized-ACE2 immunocompetent mice from SARS-CoV-2 infection. Frontiers in immunology. 2022, 13:1011185
Hiroko Iwasaki-Hozumi, Yosuke Maeda, Toshiro Niki, Haorile Chagan-Yasutan, Gaowa Bai, Takashi Matsuba, Daisuke Furushima, Yugo Ashino, Toshio Hattori. Plasma N-Cleaved Galectin-9 Is a Surrogate Marker for Determining the Severity of COVID-19 and Monitoring the Therapeutic Effects of Tocilizumab. International Journal of Molecular Sciences. 2023, 24:3591
Zhe Yuan, Leila B Giron, Colin Hart, Akwasi Gyampoh, Jane Koshy, Kai Ying Hong, Toshiro Niki, Thomas A Premeaux, Lishomwa C Ndhlovu, Claire Deleage, Luis J Montaner, Mohamed Abdel-Mohsen. Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice. AIDS, 2023, 37:571-577
Bao-Tram Thi Tran, Aurore Gelin, Sylvère Durand, Matthieu Texier, Amaury Daste, Clémence Toullec, Karim Benihoud, Ingrid Breuskin, Philippe Gorphe, Florence Garic, Catherine Brenner, Christophe Le Tourneau, Jérôme Fayette, Toshiro Niki, Muriel David, Pierre Busson, Caroline Even. Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumors. OncoImmunology. 2022, 12:2150472
N-type calcium channel and renal injury.　Bai L, Sun S, Sun Y, Wang F, Nishiyama A.　Int Urol Nephrol　54(11): 2871-2879. 2022
Glomerular deposition of galactose-deficient IgA1-containing immune complexes via glomerular endothelial cell injuries.　Makita Y, Suzuki H, Nakano N, Yanagawa H, Kano T, Novak J, Nishiyama A, Suzuki Y.　Nephrol Dial Transplant　37(9):1629-1636, 2022
Tolvaptan induces body fluid loss and subsequent water conservation in normal rats　Kidoguchi S, Kitada K, Fujisawa Y, Nakano D, Yokoo T, Titze J, Nishiyama A.　J Pharmacol Sci　149(3); 115-123, 2022
Blood pressure adaptation in vertebrates: comparative biology.　Nishiyama A, Kitada K, Suzuki M　Kidney Int　102(2): 242-247, 2022
Association of antihypertensive effects of esaxerenone with the internal sodium balance in Dahl salt-sensitive hypertensive rats.　Hattori M, Rahman A, Kidoguchi S, Jahan N, Fujisawa Y, Morisawa N, Ohsaki H, Kobara H, Masaki T, Hossain A, Steeve A, Nishiyama A.　Int J Mol Sci.　23(16): 8915, 2022
Contributions of renal water loss and skin water conservation to blood pressure elevation in spontaneously hypertensive rats.　Ogura T, Kitada K, Morisawa N, Fujisawa Y, Kidoguchi S, Nakano D, Kobara H, Masaki T, Titze J, Nishiyama A.　Hypertens Res　46(1): 32-39, 2023
Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in CT26 tumor-bearing mice.　Kittikulsuth W, Nakano D, Kitada K, Uyama T, Ueda N, Asano E, Okano K, Matsuda Y, Nishiyama A.　Sci Rep　13(1): 927, 2023
Potential Impact of Non-Steroidal Mineralocorticoid Receptor Antagonists in Cardiovascular Disease　Rahman A, Jahan N, Rahman MT, Nishiyama A.　Int J Mol Sci　24(3); 1922, 2023

Yiman Guo, Toru Uyama, S. M. Khaledur Rahman, Mohammad Mamun Sikder, Zahir Hussain, Kazuhito Tsuboi, Minoru Miyake, and Natsuo Ueda Involvement of the γ Isoform of cPLA2 in the Biosynthesis of Bioactive N-Acylethanolamines Molecules, 26, 5213 (2021)
Kazuhito Tsuboi, Tatsuya Tai, Ryouhei Yamashita, Hanif Ali, Takashi Watanabe, Toru Uyama, Yoko Okamoto, Keisuke Kitakaze, Yasuhiro Takenouchi, Shinji Go, Iffat Ara Sonia Rahman, Hitoshi Houchi, Tamotsu Tanaka, Yasuo Okamoto, Akira Tokumura, Junko Matsuda, and Natsuo Ueda Involvement of acid ceramidase in the degradation of bioactive N-acylethanolamines Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1866, 158972 (2021)
Matsuda Y, Yamashita T, Ye J, Yasukawa M, Yamakawa K, Mukai Y, Machitani M, Daigo Y, Miyagi Y, Yokose T, Oshima T, Ito H, Morinaga S, Kishida T, Minamoto T, Yamada S, Takei J, Kaneko K M, Kojima M, Kaneko S, Masaki T, Hirata M, Haba R, Kontani K, Kanaji N, Miyatake N, Okano K, Kato Y, Masutomi K. Phosphorylation of hTERT at threonine 249 is a novel tumor biomarker of aggressive cancer with poor prognosis in multiple organs. The Journal of pathology 2022 Jan 30. Epub ahead of print.
山川けいこ, 葉娟娟, 向井裕理, 成澤裕子, 松田陽子. ImageJを用いた免疫染色の定量的解析の検討. 病理と臨床. 2021年11月, 39 (11): 1163 - 1165
Suemitsu Y, Ono Y, Mizukami Y, Ye J, Yamakawa K, Takamoto T, Nakano-Narusawa Y, Mukai Y, Takamatsu M, Nakazawa A, Mino-Kenudson M, Kumasaka T, Matsuda Y. A Case of Adult Pancreatoblastoma With Novel APC Mutation and Genetic Heterogeneity. Frontiers in Oncology. 2021 Aug 27;11:725290.
Nakano-Narusawa Y, Yokohira M, Yamakawa K, Ye J, Tanimoto M, Wu L, Mukai Y, Imaida K, Matsuda Y. Relationship between Lung Carcinogenesis and Chronic Inflammation in Rodents. Cancers. 2021 Jun 10;13(12):2910
Kameyama A, Ye J, Shimomura A, Yokohira M, Nakano-Narusawa Y, Yamakawa K, Mukai Y, Sanomura T, Okuyama H, Miyatake N, Furihata M, Tanaka C, Kitazawa R, Bando Y, Suemitsu Y, Kojima M, Mino-Kenudson M, Suzuki Y, Okano K, Matsuda Y. Reproducibility and prognostic significance of area of residual tumor (ART) in post-neoajuvant resections of pancreatic ductal adenocarcinoma. Pancreatology. 2021 Sep 10;21(8):1506-1515.
K. Onishi, H.Y. Fu, T. Sofue, A. Tobiume, M. Moritoki, H. Saiga, M. Ohmura-Hoshino, K. Hoshino, T. Minamino, Galectin-9 deficiency exacerbates lipopolysaccharide-induced hypothermia and kidney injury, Clin Exp Nephrol 26 (2022) 226-233
H. Saiga, M. Ueno, T. Tanaka, T. Kaisho, K. Hoshino, Transcription factor MafB-mediated inhibition of type I interferons in plasmacytoid dendritic cells, Int Immunol 34 (2022) 159-172
Matsubara A, Miyashita T, Nakashima K, Mori N, Song SY, Hoshikawa H.Low-salt diet increases mRNA expression of aldosterone-regulated transporters in the intermediate portion of the endolymphatic sac.Pflugers Arch. 2022 May;474(5):505-515
Shi T, Gong J, Fujita K, Nishiyama N, Iwama H, Liu S, Nakahara M, Yoneyama H, Morishita A, Nonura T, Kobara H, Okano K, Suzuki Y, Masaki T. Aspirin inhibits cholangiocarcinoma cell proliferation via cell cycle arrest in vitro and in vivo. Int J Oncol　58(2): 199-210, 2021
Morishita A, Nomura K, Tani J, Fujita K, Iwama H, Takuma K, Nakahara M, Tadokoro T, Oura K, Chiyo T, Fujihara S, Niki T, Hirashima M, Nishiyama A, Himoto T, Masaki T. Galectin‑9 suppresses the tumor growth of colon cancer in vitro and in vivo. Oncol RepOncol Rep　45(6): 105, 2021
Shi T, Iwama H, Fujita K, Kobara H, Nishiyama N, Fujihara S, Goda Y, Yoneyama H, Morishita A, Tani J, Yamada M, Nakahara M, Takuma K, Masaki T. Evaluating the Effect of Lenvatinib on Sorafenib-Resistant Hepatocellular Carcinoma Cells. Int J Mol Sci　22(23): 13071, 2021
Hamaya S, Fujihara S, Iwama H, Fujita K, Shi T, Nakabayashi R, Mizuo T, Takuma K, Nakahara M, Oura K, Tadokoro T, Mimura S, Tani J, Morishita A, Kobara H, Ono M, Himoto T, Masaki T. Characterization of Cisplatin Effects in Lenvatinib-resistant Hepatocellular Carcinoma Cells. Anticancer Res　42(3): 1263-1275, 2022
Eugene Won Park, Katsuhisa Kawai, Youhei Egami, Nobukazu Araki , A novel DENND1B-localized structure found at the basal side of adherent cells. Histochemistry and cell biology
Katsuhisa Kawai, Arata Nishigaki, Seiji Moriya, Youhei Egami, Nobukazu Araki , Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264. Macrophages.Frontiers in immunology
川合克久, 荒木伸一 , Rac1 ON-OFFスイッチングによるマクロピノサイトーシスとファゴサイトーシスの時空間制御の解析. 顕微鏡
Takahashi H, Asahina R, Fujioka M, Matsui TK, Kato S, Mori E, Hioki H, Yamamoto T, Kobayashi K, Tsuboi A.Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke.Proc. Natl. Acad. Sci. USA, 118, e2018850118 (2021).
Kokudo Y, Arakawa T, Takahashi H, Kobara H, Kamada M, Deguchi K, Touge T, Masaki T, Yamamoto T.Ascending spinal tract formation in chick embryo originating from different spinal regions.Brain Res. 1768, 147595 (2021).
Wan N, Rahman A, Nishiyama A. Esaxerenone, a novel nonsteroidal mineralocorticoid receptor blocker (MRB) in hypertension and chronic kidney disease. J Hum Hypertens
Zhang A, Nakano D, Morisawa N, Kitada K, Kittikulsuth W, Rahman A, Morikawa T, Konishi Y, Nishiyama A. Effects of molidustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, on sodium dynamics in hypertensive subtotally nephrectomized rats. J Pharmacol Sci
Zhang A, Nakano D, Kittikulsuth W, Yamashita Y, Nishiyama A. Luseogliflozin, a SGLT2 inhibitor, does not affect glucose uptake kinetics in renal proximal tubules of live mice. Int J Mol Sci
Godoy-Lugo JA, Thorwald MA, Hui DY, Nishiyama A, Nakano D, Soñanez-Organis JG, Ortiz RM. Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats. Endocrine
Kitada K, Kidoguchi S, Nakano D, Nishiyama A. Sodium/glucose cotransporter 2 and renoprotection: From the perspective of energy regulation and water conservation. J Pharmacol Sci
Kittikulsuth W, Nakano D, Kitada K, Suzuki N, Yamamoto M, Nishiyama A. Renal NG2-expressing cells have a macrophage-like phenotype and facilitate renal recovery after ischemic injury. Am J Physiol Renal Physiol
Rodriguez R, Lee A, Godoy-Lugo J, Martinez B, Ohsaki H, Nakano D, Parkes D, Nishiyama A, Vazquez-Medina JP, Ortiz R. Chronic AT1 blockade improves hyperglycemia by decreasing adipocyte inflammation and decreasing hepatic PCK1 and G6PC1 expression in obese rats. Am J Physiol Endocrinol Metab
Cornejo MA, Dhillon J, Nishiyama A, Nakano D, Rudy M, Ortiz RM. Mass recovery following caloric restriction reverses lipolysis and proteolysis, but not gluconeogenesis, in insulin resistant OLETF rats. PLoS One
Kidoguchi S, Kitada K, Nakajima K, Nakano D, Ohsaki H, Kittikulsuth W, Kobara H, Masaki T, Yokoo T, Takahashi K, TitzeJ, Nishiyama A. Hepatocellular carcinoma induces body mass loss in parallel with osmolyte and water retention in rats. Life Sci
Morishita A, Tadokoro T, Fujihara S, Iwama H, Oura K, Fujita K, Tani J, Takuma K, Nakahara M, Shi T, Haba R, Okano K, Nishiyama A, Ono M, Himoto T, Masaki T. Ipragliflozin attenuates non-alcoholic steatohepatitis development in an animal model. PLoS One
Gaowa Bai, Daisuke Furushima, Toshiro Niki, Takashi Matsuba, Yosuke Maeda, Atsushi Takahashi, Toshio Hattori, Yugo Ashino. High levels of the cleaved form of galectin-9 and osteopontin in the plasma are associated with inflammatory markers that reflect the severity of COVID-19 pneumonia. Int. J. Mol. Sci. 2021, 22(9), 4978
"Asahiro Morishita, Kei Nomura, Joji Tani, Koji Fujita, Hisakazu Iwama, Kei Takuma, Mai Nakahara, Tomoko Tadokoro, Kyoko Oura, Taiga Chiyo, Shintaro Fujihara, Toshiro Niki, Mitsuomi Hirashima, Akira Nishiyama, Takashi Himoto, Tsutomu Masaki. Galectin‑9 suppresses the tumor growth of colon cancer in vitro and in vivo. Oncol Rep. 2021 Jun;45(6):105"
Gaowa Bai, Takashi Matsuba, Toshiro Niki, Toshio Hattori. Efficient Production of Osteopontin-Encapsulating Exosome by LPS Stimulated THP-1 Macrophages. Recent Research Advances in Biology Vol. 11 Page 83-96
Natasha Ustyanovska Avtenyuk, Ghizlane Choukrani, Emanuele Ammatuna, Toshiro Niki, Ewa Cendrowicz, Harm Jan Lourens, Gerwin Huls, Valerie R Wiersma, Edwin Bremer. Galectin-9 Triggers Neutrophil-Mediated Anticancer Immunity. Biomedicines 2022, 10(1), 66
Asif J Iqbal, Franziska Krautter, Isobel A Blacksell, Rachael D Wright, Shani N Austin‐Williams, Mathieu‐Benoit Voisin, Mohammed T Hussain, Hannah L Law, Toshiro Niki, Mitsuomi Hirashima, Michele Bombardieri, Costantino Pitzalis, Alok Tiwari, Gerard B Nash, Lucy V Norling, Dianne Cooper. Galectin‐9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin‐dependent manner. FASEB J. 2022 Jan;36(1):e22065
Dainichi T, Kaku Y, Izumi M, Kataoka K, Morishita Y, Koga H, Ishii N. Anti-BP230-type papular non-bullous pemphigoid with granular immunoglobulin G deposition at the papillary dermis. J Dermatol (2021) 48(10):E517-E519.
Suezawa M, Dainichi T, Kaku Y, Izumi M, Kataoka K, Ishii N, Koga H, Izumi K, Nishie W. Dipeptidyl peptidase 4 inhibitor-associated mucous membrane pemphigoid. J Dermatol (2021) 48(10):1584-1587.
Hiraishi K, Zhao F, Kurahara LH*, Li X, Yamashita T, Hashimoto T, Matsuda Y, Sun Z, Zhang H, Hirano K:　Lactulose modulates the structure of gut microbiota and alleviates colitis-associated tumorigenesis.Nutrients 14(3): 649, 2022
Yaopeng Hu*, Qin Li, Lin-Hai Kurahara, Narumi Shioi, Keizo Hiraishi, Takayuki Fujita, Xin Zhu and Ryuji Inoue* An Arrhythmic Mutation E7K Facilitates TRPM4 Channel Activation via Enhanced PIP2 Interaction / Cells 2021, 10(5), 983;
Xu H, Hiraishi K, Kurahara L-H*, Nakano-Narusawa Y, Li X, Hu Y, Matsuda Y, Zhang H, Hirano K: Inhibitory effects of breast milk-derived Lactobacillus rhamnosus Probio-M9 on colitis-associated carcinogenesis by restoration of the gut microbiota in a mouse model. Nutrients 13(4): 1143, 2021 *責任著者
Hiraishi K, Kurahara L-H*, Feng J, Yamamura A, Cui Y, Yahiro E, Yokomise H, Go T, Ishikawa K, Yokota N, Fujiwara A, Onitsuka M, Abe K, Ohga S, Satoh T, Okada Y, Yue L, Inoue R, Hirano K: Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension. Translational Research 2021 2021233: 127-143 doi: 10.1016/j.trsl.2021.03.004.

Eugene Won Park,Katsuhisa Kawai,Youhei Egami,Nobukazu Araki,A novel DENND1B-localized structure found at the basal side of adherent cells. Histochem Cell Biol. 2021 Jan;155(1):9-18
Katsuhisa Kawai, Arata Nishigaki, Seiji Moriya, Youhei Egami, Nobukazu Araki,Rab10-Positive Tubular Structures Represent a Novel Endocytic Pathway That Diverges From Canonical Macropinocytosis in RAW264 Macrophages. Front Immunol. 2021 May 31;12:649600
Nakano Y, Hirooka K, Chiba Y, Ueno M, Ojima D, Hossain MR, Takahashi H, Yamamoto T, Kiuchi Y. Retinal ganglion cell loss in 1 kinesin-1 cargo Alcadein α deficient mice. Cell Death Dis. 11, 166 (2020).
Gotoh N, Saito Y, Hata S, Saito H, Ojima D, Murayama C, Shigeta M, Abe T, Konno D, Matsuzaki F, Suzuki T, Yamamoto T. Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice. J. Biol. Chem., 295, 9650-9662 (2020).
Kuboyama K, Shirakawa Y, Kawada K, Fujii N, Ojima D, Kishimoto Y, Yamamoto T, Yamada MK. Visually cued fear conditioning test for memory impairment related to cortical function. Neuropsychopharmacol. Rep. 40, 371-375 (2020).
Xu H, Hiraishi K, Kurahara L-H*, Nakano-Narusawa Y, Li X, Hu Y, Matsuda Y, Zhang H, Hirano K:　Inhibitory effects of breast milk-derived Lactobacillus rhamnosus Probio-M9 on colitis-associated carcinogenesis by restoration of the gut microbiota in a mouse model.　　Nutrients 13: 1143, 2021　原著論文
Hiraishi K, Kurahara L-H*, Feng J, Yamamura A, Cui Y, Yahiro E, Yokomise H, Go T, Ishikawa K, Yokota N, Fujiwara A, Onitsuka M, Abe K, Ohga S, Satoh T, Okada Y, Yue L, Inoue R, Hirano K:　Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension.　　Transl Res (233, P 127-143, 2021)　原著論文
Kurahara LH*, Hiraishi K, Yamamura A, Zhang Y, Abe K, Yahiro E, Aoki M, Koga K, Yokomise H, Go T, Ishikawa K, Zhang B, Kishi H, Kobayashi S, Aoki-Shoi N, Satoh T, Inoue R, Hirano K:　Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn.　　J Mol Cell Cardiol 148: 50-62, 2020　原著論文
Ashwini Shete, Shubhangi Bichare, Vishwanath Pujari, Rashmi Virkar, Madhuri Thakar, Manisha Ghate, Sandip Patil, Annapurna Vyakarnam, Raman Gangakhedkar, Gaowa Bai, Toshiro Niki, Toshio Hattori. Elevated Levels of Galectin-9 but Not Osteopontin in HIV and Tuberculosis Infections Indicate Their Roles in Detecting MTB Infection in HIV Infected Individuals. Front Microbiol. 2020; 11: 1685.
Gaowa Bai, Takashi Matsuba, Toshiro Niki, Toshio Hattori. Stimulation of THP-1 Macrophages with LPS Increased the Production of Osteopontin-Encapsulating Exosome. Int. J. Mol. Sci. 2020, 21(22), 8490
Gaowa Bai, Toshiro Niki, Haruhisa Kikuchi, Ayako Sumi, Nobuyuki Kobayashi, Takahiro Haruyama, Jing Zhang, Haorile Chagan-Yasutan, Toshio Hattori. New Development of Disaster-Related and Tropical Infectious Diseases Control. Reports 2020, 3(1), 5
Haorile Chagan-Yasutan, Firmanto Hanan, Toshiro Niki, Gaowa Bai, Yugo Ashino, Shinichi Egawa, Elizabeth Freda O Telan, Toshio Hattori. Plasma osteopontin levels is associated with biochemical markers of kidney injury in patients with leptospirosis. Diagnostics 2020, 10(7), 439
Shirley T Padilla, Toshiro Niki, Daisuke Furushima, Gaowa Bai, Haorile Chagan-Yasutan, Elizabeth Freda Telan, Rosario Jessica Tactacan-Abrenica, Yosuke Maeda, Rontgene Solante, Toshio Hattori. Plasma levels of a cleaved form of galectin-9 are the most sensitive biomarkers of acquired immune deficiency syndrome and tuberculosis coinfection. Biomolecules 2020, 10(11), 1495
Gaowa Bai, Daisuke Furushima, Toshiro Niki, Takashi Matsuba, Yosuke Maeda, Atsushi Takahashi, Toshio Hattori, Yugo Ashino. High Levels of the Cleaved Form of Galectin-9 and Osteopontin in the Plasma Are Associated with Inflammatory Markers That Reflect the Severity of COVID-19 Pneumonia. Int. J. Mol. Sci. 2021, 22(9), 4978
Tomokazu Nunoue, Satoshi Yamaguchi, Sanae Teshigawara, Akihiro Katayama, Atsuko Nakatsuka, Jun Eguchi, Toshiro Niki, Jun Wada. Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2. Scientific Reports volume 11, Article number: 5991 (2021)
Miyazaki, R., Saiga, H., Kato, T., Bakoshi, T., Senba, R., Shintani, A., Suzuki, M., Takao, K., Sasaki, I., Iizuka, A., Sugiyama, M., Iwami, N., Fukuda-Ohta, Y., Hemmi, H., Tanaka, T., Miyake, M., Kaisho, T., and Hoshino, K. (2020). The mechanism of action of Spi-B in the transcriptional activation of the interferon-alpha4 gene. Biochem Biophys Res Commun 525, 477-482, 10.1016/j.bbrc.2020.02.101.
Tenkumo C, Ohta KI, Suzuki S, Warita K, Irie K, Teradaya S, Kusaka T, Kanenishi K, Hata T, Miki T. Repeated maternal separation causes transient reduction in BDNF expression in the medial prefrontal cortex during early brain development. Heliyon 6(8) (2020) Suzuki S, Ohta KI, Nakajima Y, Shigeto H, Abe H, Kawai A, Miura R, Kazuki Y, Oshimura M, Miki T. Meganuclease-Based Artificial Transcription Factors. ACS Synth Biol. 9(10) (2020) 2679-2691
Metformin Inhibits Proliferation and Tumor Growth of QGP-1 Pancreatic Neuroendocrine Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis. Anticancer Res,40(1): 121-132, 2020
Role of microRNA-210-3p in hepatitis B virus-related hepatocellular carcinoma.Am J Physiol Gastrointest Liver Physiol,318(3): G401-G409 , 2020
Antihypertensive drug telmisartan suppresses the proliferation of gastric cancer cells in vitro and in vivo. Oncol Rep,44(1): 339-348, 2020
Aspirin inhibits hepatocellular carcinoma cell proliferation in vitro and in vivo via inducing cell cycle arrest and apoptosis. Oncol Rep,44: 457-468, 2020
Comprehensive analysis of circulating microRNAs as predictive biomarkers for sorafenib therapy outcome in hepatocellular carcinoma. Oncol Lett,20(2): 1727-1733, 2020
Molecular and Functional Roles of MicroRNAs in the Progression of Hepatocellular Carcinoma-A Review. Int J Mol Sci,21(21): 8362, 2020
MicroRNAs in the Pathogenesis of Hepatocellular Carcinoma: A Review. Cancers(Basel),13(3): 514, 2021
Aspirin inhibits cholangiocarcinoma cell proliferation via cell cycle arrest in vitro and in vivo.Int J Oncol,58(2): 199-210, 2021
A.Itoh, Y.Nonaka, SI.Nakakita, H.Yoshida, N.Nishi, T.Nakamura, S.Kamitori, Structures of human galectin-10/monosaccharide complexes demonstrate potential of monosaccharides as effectors in forming Charcot-Leyden crystals. Biochemical and Biophysical Research Communications Vol.525,No1(2021)87-93. https ://doi.org/10.1016/j.bbrc.2020.02.037

Li L, Guan Y, Kobori H, Morishita A, Koboara H, Masaki T, Nakano D, Nishiyama A .Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive hypertensive rats.Hypertens Res. 2019 Jun;42(6)769-778.
EBhuiyan AS, Rafiq K, Kobara H, Masaki T, Nakano D, Nishiyama A. Effect of a novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice.Hypertens Res. 2019 Jun;42(6):892-902, .
Koizumi M, Ueda K, Niikura F, Nishiyama A, Yanagita M, Saito A, Pastan I, Fujita T, Fukagawa M, Matsusaka T.　Podocyte injury augments intrarenal angiotensin II generation and sodium retention in a megalin-dependent manner.Hypertension. 2019 Jul;74(3):509-517.
Guan Y, Nakano D, Zhang Y, Li L, Tian Y, Nishiyama A.　A mouse model of renal fibrosis to overcome the technical variability in ischaemia/reperfusion injury among operators.Scientific Reports 2019 Jul, 18;9(1):10435.
Koyano T, Namba M, Kobayashi T, Nakakuni K, Nakano D, Fukushima M, Nishiyama A, Matsuyama M　The p21 Dependent G2 Arrest of the Cell Cycle in Epithelial Tubular Cells Links to the Early Stage of Renal FibrosisSci Rep, 2019: 9(1),12059.
Yoshida A, Endo J, Kinouchi K, Kitakata H, Moriyama H, Kataoka M, Yamamoto T, Shirakawa K, Morimoto S, Nishiyama A, Hashiguchi A, Higuchi I, Fukuda K, Ichihara A, Sano M(Pro)renin Receptor Accelerates Development of Sarcopenia via Activation of Wnt/YAP Signaling AxisAging Cell, 2019; 18(5),e12991.
新規MRブロッカー　森澤紀彦、西山　成　カレントテラピー: 37(6):595-599, 2019
皮膚と食塩の意外な関係　森澤紀彦、北田研人、西山　成　循環器内科: 85(6):821-826, 2019
エサキセレノン錠　森澤紀彦、西山　成　血圧: 26(8):500-503,2019
新規ミネラルコルチコイド受容体ブロッカーエサキセレノンとは　森澤紀彦、菅野直希、西山　成　循環器内科: 86(2):152-156,2019
食塩摂取が尿素代謝に与える影響　森澤紀彦、北田研人、西山　成　日本抗加齢医学会: 15(5):53-57,2019
生体イメージングを活用した腎病態生理機構の解明　中野大介　日本腎臓学会誌: 61(8):1144-1148,2019
Yamakawa K, Nakano-Narusawa Y, Hashimoto N, Yokohira M, Matsuda Y. Development and clinical trials of nucleic acid medicines for pancreatic cancer treatment. Int. J. Mol. Sci. 20: pii:E4224, 2019.
Kishi S, Yamakawa K, Nakano-Narusawa Y, Kanie S, Hashimoto N, Saoo K, Yokohira M, Imaida K, Matsuda Y.Preexisting diabetes mellitus had no effect on the no-observed-adverse-effect-level of acetaminophen in rats.J. Toxicol. Sci., 45(3):151-162, 2020.
Matsuda YAge-related morphological changes in the pancreas and their association with pancreatic carcinogenesis. Pathol Int. 2019 Aug;69(8):450-462.
Akiyama M, Matsuda Y, Arai T, Saeki H.PD-L1 expression in malignant melanomas of the skin and gastrointestinal tract. Oncol Lett. 2020 Mar;19(3):2481-2488.
Wang T, Matsuda Y, Nonaka K, Kakizaki M, Ishiwata T, Kanazawa N, Uegaki S, Muramatsu M, Sawabe M, Mori S, Tanaka M, Kitagawa M, Arai T.Clinicopathological characteristics of gastric cancer with carbohydrate antigen 19-9 expression occurring in elderly individuals: An autopsy study. Pathol Int. 2020 Feb;70(2):92-100.
Okubo S, Kojima M, Matsuda Y, Hioki M, Shimizu Y, Toyama H, Morinaga S, Gotohda N, Uesaka K, Ishii G, Mino-Kenudson M, Takahashi S.
Area of residual tumor (ART) can predict prognosis after post neoadjuvant therapy resection for pancreatic ductal adenocarcinoma. Sci Rep. 2019 Nov 20;9(1):17145.
Yasukawa M, Ando Y, Yamashita T, Matsuda Y, Shoji S, Morioka MS, Kawaji H, Shiozawa K, Machitani M, Abe T, Yamada S, Kaneko MK, Kato Y, Furuta Y, Kondo T, Shirouzu M, Hayashizaki Y, Kaneko S, Masutomi K. CDK1 dependent phosphorylation of hTERT contributes to cancer progression. Nat Commun. 2020 Mar 25;11(1):1557.
Galectin-9 Induces Mitochondria-Mediated Apoptosis of Esophageal Cancer In Vitro and In Vivo in a Xenograft Mouse Model. Int J Mol Sci,20: E2634
Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo. Int J Mol Sci,20(13): E3197
Metformin Inhibits Proliferation and Tumor Growth of QGP-1 Pancreatic Neuroendocrine Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis. Anticancer Res,40(1): 121-132
Hiromi Yoshida, Katsuhiro Kojima, Masaki Shiota, Keiichi Yoshimatsu, Tomohiko Yamazaki, Stefano Ferri, Wakako Tsugawa, Shigehiro Kamitori and Koji Sode,
X-ray structure of the direct electron transfer-type FAD glucose dehydrogenase catalytic subunit complexed with a hitchhiker protein.
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Tamai E, Katayama S, Sekiya H, Nariya H, Kamitori S., Structures of major pilins in Clostridium perfringens demonstrate dynamic conformational change. Acta Crystallogr D Struct Biol. Vol75, No8 (2019), 718-732. doi: 10.1107/S2059798319009689.

Tricellulin Expression and its Deletion Effects in the Endolymphatic Sac.Matsubara A, Miyashita T, Inamoto R, Sakaguchi H, Kamitani T, Mori N, Hoshikawa H.J Int Adv Otol. 2018 Aug;14(2):312-316. doi: 10.5152/iao.2018.5473.
Zahir Hussain, Toru Uyama, Katsuhisa Kawai, Smriti Sultana Binte Mustafiz, Kazuhito Tsuboi, Nobukazu Araki, and Natsuo Ueda Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca2+-dependent N-acyltransferaseBiochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1863, 493-502 (2018)
Smriti Sultana Binte Mustafiz, Toru Uyama, Zahir Hussain, Katsuhisa Kawai, Kazuhito Tsuboi, Nobukazu Araki, and Natsuo Ueda　The role of intracellular anionic phospholipids in the production of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2εJournal of Biochemistry, 165, 343-352 (2019)
Kazuhito Tsuboi, Toru Uyama, Yasuo Okamoto, and Natsuo Ueda Endocannabinoids and related N-acylethanolamines: biological activities and metabolism,Inflammation and Regeneration, 38, 28, (2018)
Murakami A, Maekawa M, Kawai K, Nakayama J, Araki N, Semba K, Taguchi T, Kamei Y, Takada Y, Higashiyama S., Cullin-3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2-positive breast cancer cells. Cancer Sci., 2019 Feb;110(2):650-661.
Selective peroxisome proliferator-activated receptor-α modulator K-877 regulates the expression of ATP-binding cassette transporter A1 in pancreatic beta cells. Dong T, Lyu J, Imachi H, Kobayashi T, Fukunaga K, Sato S, Ibata T, Yoshimoto T, Yonezaki K, Iwama H, Zhang G, Murao K.,Eur J Pharmacol. 2018 Nov 5;838:78-84.
Effect of TNF-α on the expression of ABCA1 in pancreatic β-cells. Sato S, Imachi H, Lyu J, Miyai Y, Fukunaga K, Dong T, Ibata T, Kobayashi T, Yoshimoto T, Kikuchi F, Yonezaki K, Yamaji N, Iwama H, Murao K.,J Mol Endocrinol. 2018 Oct 15;61(4):185-193.
IGF1 suppresses cholesterol accumulation in the liver of growth hormone-deficient mice via the activation of ABCA1. Fukunaga K, Imachi H, Lyu J, Dong T, Sato S, Ibata T, Kobayashi T, Yoshimoto T, Yonezaki K, Matsunaga T, Murao K.,Am J Physiol Endocrinol Metab. 2018 Dec 1;315(6):E1232-E1241.
Angiotensin II induces cholesterol accumulation and impairs insulin secretion by regulating ABCA1 in beta cells. Lyu J, Imachi H, Fukunaga K, Sato S, Ibata T, Kobayashi T, Dong T, Yoshimoto T, Yonezaki K, Nagata H, Iwama H, Murao K.,J Lipid Res. 2018 Oct;59(10):1906-1915.
A Case of Co-existing of Neuromyelitis Optica and Fulminant Type 1 Diabetes. Saheki T, Imachi H, Ibata T, Fukunaga K, Yoshioka Y, Kobayashi T, Sato S, Mizumoto K, Yoshimoto T, Lyu J, Dong T, Murao K.,Intern Med. 2019 Mar 28. doi: 10.2169/internalmedicine.2353-18. [Epub ahead of print]
Bilateral Adrenocortical Adenomas along with Virilization and Cushing's Syndrome. Kobayashi T, Imachi H, Sato S, Ibata T, Fukunaga K, Yoshimoto T, Kikuchi F, Yonezaki K, Yamaji N, Lyu J, Dong T, Nagata H, Kadota K, Kushida Y, Haba R, Murao K.,Intern Med. 2019 Feb 1;58(3):405-409. doi: 10.2169/internalmedicine.0790-18. Epub 2018 Sep 12.
D. S. Retnoningrum, Hiromi Yoshida, S. Arumsari, Shigehiro Kamitori & W. T. Ismaya, "The first crystal structure of manganese superoxide dismutase from the genus Staphylococcus.", Acta crystallogr F 74(2), 135-142, (2018)
Hiromi Yoshida, Akihide Yoshihara, Pushpa Kiran Gullapalli, Kohei Ohtani, Kazuya Akimitsu, Ken Izumori and Shigehiro Kamitori, " X-ray structure of Arthrobacter globiformis M30 ketose 3-epimerase for the production of D-allulose from D-fructose.", Acta crystallogr F 74(10), 669-676, (2018)
Colomb F, Giron LB, Premeaux TA, Mitchell BI, Niki T, Papasavvas E, Montaner LJ, Ndhlovu LC, Abdel-Mohsen M. Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling. Front Immunol. 2019 Feb 20;10:267. doi: 10.3389/fimmu.2019.00267.
Niki T, Fujita K, Rosen H, Hirashima M, Masaki T, Hattori T, Hoshino K. Plasma Galectin-9 Concentrations in Normal and Diseased Condition. Cell Physiol Biochem. 2018;50(5):1856-1868. doi: 10.1159/000494866.
Lhuillier C, Barjon C, Baloche V, Niki T, Gelin A, Mustapha R, Clae¨r L, Hoos S, Chiba Y, Ueno M, Hirashima M, Wei M, Morales O, Raynal B, Delhem N, Dellis O, Busson P. Characterization of neutralizing antibodies reacting with the 213-224 amino-acid segment of human galectin-9. PLoS One. 2018 Sep 11;13(9):e0202512. doi: 10.1371/journal.pone.0202512.
Zeggar S, Watanabe KS, Teshigawara S, Hiramatsu S, Katsuyama T, Katsuyama E, Watanabe H, Matsumoto Y, Kawabata T, Sada KE, Niki T, Hirashima M, Wada J. Role of Lgals9 Deficiency in Attenuating Nephritis and Arthritis in BALB/c Mice in a Pristane-Induced Lupus Model. Arthritis Rheumatol. 2018 Jul;70(7):1089-1101. doi: 10.1002/art.40467.
Kayama, H., M. Kohyama, D. Okuzaki, D. Motooka, S. Barman, R. Okumura, M. Muneta, K. Hoshino, I. Sasaki, W. Ise, H. Matsuno, J. Nishimura, T. Kurosaki, S. Nakamura, H. Arase, T. Kaisho, and K. Takeda. 2018. Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles. Proceedings of the National Academy of Sciences of the United States of America 115: 8418-8423.
Simultaneous GLP-1 receptor activation and angiotensin receptor blockade increase natriuresis independent of altered arterial pressure in obese OLETF rats.Rodriguez R, Moreno M, Lee1 AY, Godoy-Lugo JA, Nakano D, Nishiyama A, Parkes DG, Awayda MS, Ortiz RM. Hypertens Res. 2018 Oct;41(10):798-808.
Guanylyl cyclase A in both renal proximal tubular and vascular endothelial cells protects the kidney against acute injury in rodent experimental endotoxemia models.Kitamura H, Nakano D, Sawanobori Y, Asaga T, Yokoi H, Yanagita M, Mukoyama M, Tokudome T, Kangawa K, Shirakami G, Nishiyama A. Anesthesiology. 2018 Aug;129(2):296-310. doi: 10.1097/ALN.0000000000002214.
Acute kidney injury to chronic kidney disease transition: insufficient cellular stress response.Strausser SA, Nakano D, Souma T. Curr Opin Nephrol Hypertens. 2018 Jul;27(4):314-322. doi: 10.1097/MNH.0000000000000424. 　
Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats.Thorwald M, Rodriguez R, Lee A, Martinez B, Peti-Peterdi J, Nakano D, Nishiyama A, Ortiz RM. Redox Biol. 2018 Apr; 14: 371-378.
A sodium-glucose cotransporter 2 inhibitor attenuates renal capillary injury and fibrosis by a vascular endothelial growth factor-dependent pathway after renal injury in mice.Zhang Y, Nakano D, Guan Y, Hitomi H, Uemura A, Masaki T, Kobara H, Sugaya Y, Nishiyama A. Kidney Int. 2018 Sep;94(3):524-535.
The effects of sodium-glucose cotransporter 2 inhibitors on sympathetic nervous activity. Wan N, Rahman A, Hitomi H, Nishiyama A. Front Endocrinol. 26 July 2018 | https://doi.org/10.3389/fendo.2018.00421
Angiotensin receptor and tumor necrosis factor-α activation contributes to glucose intolerance independent of systolic blood pressure in obese rats.
Rodriguez R, Lee A, Mathis KW, Broome HJ, Thorwald M, Martinez B, Nakano D, Nishiyama A, Ryan MJ, Ortiz RM. Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1081-F1090.
Effects of the selective chymase inhibitor TEI-F00806, on the intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice. Ansary TM, Urushihara M, Fujisawa Y, Nagata S, Urata H, Nakano D, Hirofumi H, Kitamura K, Kagami S, Nishiyama A. Exp Physiol. Nov 2018 Nov; 103(11): 1524-1531.
Nrf2-related gene expression is impaired during a glucose challenge in type II diabetic rat hearts. horwald MA, Godoy-Lugo JA, Rodriguez GJ, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM. Free Radic Biol Med. Volume130, 2019 Jan: 306-317.
(Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations. Wang J. Shibayama Y, Zhang A, Ohsaki H, Asano E, Suzuki Y, Kushida Y, Kobara H, Masaki T, Wang Z, Nishiyama A. Br J Cancer. 2019 Jan;120(2):229-237.
Effect of a novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice. Bhuiyan AS, Rafiq K, Kobara H, Masaki T, Nakano D, Nishiyama A. Hypertens Res. 2019 Jun;42(6)769-778.
SGLT2阻害薬と血圧日内変動　人見浩史、西山　成　血圧, 25(4): 226-227, 2018
異分野から行き着いたがん研究「（プロ）レニン受容体」　西山　成　日本がん予防学会NEWSLETTER,: 97：5-6 2018
食塩感受性高血圧ラットにおいて生じた腎組織障害は、減塩とＡＲＢ・ＣＣＢによる厳密な降圧により後退しうる　西山　成、Kazi R、森川　貴、柴田幹子、岸田真嗣、濱田真宏、北林千津子、小西啓夫、今西政仁　腎とフリーラジカル, 13：78-79 2018

Hasan AU, Ohmori K, Hashimoto T, Kamitori K, Yamaguchi F, Noma T, Igarashi J, Tsuboi K, Tokuda M, Nishiyama A, Kohno M.GPR120 in adipocytes has differential roles in the production of pro-inflammatory adipocytokines. Biochem Biophys Res Commun. 2017 Apr 22;486(1):76-82.
Yoshimoto T, Furuki T, Kobori H, Miyakawa M, Imachi H, Murao K, Nishiyama A.Effects of sodium glucose cotransporter 2 inhibitors on urinary excretion of intact and total angiotensinogen in patients with type 2 diabetes. J Investig Med. 2017 Oct;65(7):1057-1061
Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schro¨der A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Mu¨ller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J.High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.J Clin Invest. 2017 May 1;127(5):1944-1959.
Hasan AU, Kittikulsuth W, Yamaguchi F, Ansary TM, Rahman A, Shibayama Y, Nakano D, Hitomi H, Tokuda M, Nishiyama A. IBMX protects human proximal tubular epithelial cells from hypoxic stress through suppressing hypoxia-inducible factor-1α expression.Exp Cell Res. 2017, Sep 15;358(2):343-351.
Hitomi H, Nishiyama A.How should we treat patients with primary aldosteronism to prevent new-onset diabetes mellitus? J Hypertens., 35(8): 1575-6, 2017
Kitada K, Nishiyama A. Sodium intake affects gender difference in aldosterone concentration.0Am J Physiol Renal Physiol. 2017, Aug 9;313:957-958.
Ansary T, Fujisawa Y, Rahman A, Nakano D, Hitomi H, Kobara H, Masaki T, Titze JM, Kitada K, Nishiyama A.Responses of renal hemodynamics and tubular functions to acute sodium-glucose cotransporter 2 inhibitor administration in non-diabetic anesthetized rats.Sci Rep. 2017, Aug 25;7(1):9555.
Guan Y, Nakano D, Zhang Y, Li L, Liu W, Nishida M, Kuwabara T, Morishita A, Hitomi H, Mori K, Mukoyama M, Masaki T, Hirano K, Nishiyama A. A protease-activated receptor-1 antagonist protects against podocyte injury in a mouse model of nephropathy. J Pharmacol Sci. 2017, Sep 14. pii: S1347-8613(17)30128-7.
Wang J, Shibayama Y, Kobori H, Liu Y, Kobara H, Masaki T, Wang Z, Nishiyama A.High glucose augments angiotensinogen in human renal proximal tubular cells through hepatocyte nuclear factor-5.PLoS ONE. 2017, Nov 9;12(11):e0187894.
Sofue T, Kushida Y, Ozaki T, Moritoki M, Nishijima Y, Ohsaki H, Ueda N, Kakehi Y, Nishiyama A, Minamino T.2 Tubular cell senescence in the donated kidney predicts allograft function, but not doner remnant kidney function, in living donor kidney transplantation.Am J Nephrol. 2017, Dec 22;47(1):8-17.
Yamazaki D, Hitomi H, Nishiyama A. Hypertension with diabetes mellitus “Complications”.Hypertens Res. 2018 Jan 22. doi: 10.1038/s41440-017-0008-y.
Hifumi T, Nakano D, Chiba J, Takahashi M, Yamamoto A, Fujisawa Y, Kuroda Y, Kawakita K, Nihsiyama A.Combined therapy with gas gangrene antitoxin and recombinant human soluble thrombomodulin for clostridium perfringens sepsis in a rat model. Toxicon. 2018 Jan;141:112-117.
Rahman A, Hasan A, Nishiyama A, Kobori H.Altered circadian timing system-mediated non-dipping pattern of blood pressure and associated cardiovascular disorders in metabolic and kidney diseases. Int J Mol Sci. 2018 Jan 30;19(2). pii: E400.
Rahman A, Yamazaki D, Sufiun A, Kitada K, Hitomi H, Nakano D, Nishiyama A. A novel approach to adenine-induced chronic kidney disease associated anemia in rodents. PLoS ONE. 2018 Feb 7;13(2):e0192531.
Strausser SA, Nakano D, Souma T.Acute kidney injury to chronic kidney disease transition-insufficient cellular stress response.Curr Opin Nephrol Hypertens. 2018 Apr 26. doi: 10.1097/MNH.0000000000000424.
Takami T, Okada S, Saito Y, Nishijima Y, Kobori H, Nishiyama A.Effects of Olmesartan and Azilsartan on Albuminuria and the Intrarenal Renin-Angiotensin System.World J Res Rev. 2018 Jan;6(1):7-10.
T. Akazawa, M. Ogawa, S. Hayakawa, M. Hirata, and T. Niwa, Structural change of ovalbumin-related protein X by alkali treatment. Poultry Science, Vol. 97,(2018) 1730-1737
T. Shimasaki, H. Yoshida, S. Kamitori, K. Sode, X-ray structures of fructosyl peptide oxidases revealing residues responsible for gating oxygen access in the oxidative half reaction., Sci Rep., 7(1), 2790, (2017)
H. Yoshida, N. Nishi, K. Wada, T. Nakamura, M. Hirashima, N. Kuwabara, R. Kato, S. Kamitori, X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site., Biochem Biophys Res Commun. 490(4), 1287-1293, (2017)
Tamai E, Sekiya H, Maki J, Nariya H, Yoshida H, Kamitori S., X-ray structure of Clostridium perfringens sortase B cysteine transpeptidase., Biochem Biophys Res Commun. 493(3), 1267-1272, (2017)
Ikeda Y, Kawai K, Ikawa A, Kawamoto K, Egami Y, Araki N., Rac1 switching at the right time and location is essential for Fcγ receptor-mediated phagosome formation. J Cell Sci. 2017 Aug 1;130(15):2530-2540.
Egami Y, Kawai K, Araki N., RhoC regulates the actin remodeling required for phagosome formation during FcγR-mediated phagocytosis. J Cell Sci. 2017 Dec 15;130(24):4168-4179.
Connor SA, Ammendrup-Johnsen I, Kishimoto Y, Karimi Tari P, Cvetkovska V, Harada T, Ojima D, Yamamoto T, Wang YT, Craig AM.Loss of synapse repressor MDGA1 enhances perisomatic inhibition, confers resistance to network excitation, and impairs cognitive function.Cell Rep. 21, 3637-3645 (2017).
Yamashita T, Inaoka DK, Shiba T, Oohashi T, Iwata S, Yagi T, Kosaka H, Miyoshi H, Harada S, Kita K, Hirano K, Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors., Scientific Reports (2018) 8, 2427
三木崇範、太田健一、鈴木辰吾　毒性のメカニズムと症候－エタノール　Clinical Neuroscience, Vol.35, No.12 (2017) 1393-1397
Toru Uyama, Kazuhito Tsuboi, and Natsuo Ueda An involvement of phospholipase A/acyltransferase family proteins in peroxisome regulation and plasmalogen metabolismFEBS Letters, 591, 2745-2760, (2017)
Manami Inoue, Kazuhito Tsuboi, Yoko Okamoto, Mayumi Hidaka, Toru Uyama, Toshihiko Tsutsumi, Tamotsu Tanaka, Natsuo Ueda, and Akira Tokumura
Peripheral tissue levels and molecular species compositions of N-acyl-phosphatidylethanolamine and its metabolites in mice lacking N-acyl-phosphatidylethanolamine-specific phospholipase D Journal of Biochemistry, 162, 449-458 (2017)
Zahir Hussain, Toru Uyama, Kazuhito Tsuboi, and Natsuo Ueda Mammalian enzymes responsible for the biosynthesis of N-acylethanolamines Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862, 1546-1561, (2017)
Smriti Sultana Binte Mustafiz, Toru Uyama, Zahir Hussain, Kazuhito Tsuboi, and Natsuo Ueda The Biosynthetic Pathways of N-acylethanolamines in Mammals eLS, article ID: a0027711, (2018)
坪井　一人、宇山　徹、上田　夏生グリセロホスホジエステラーゼ・ファミリーによるN-アシルエタノールアミンおよびリゾホスファチジン酸の生成ビタミン、91, 489-496 (2017)
宇山　徹、上田　夏生 PLAAT (PLA2G16) ファミリー医学のあゆみ、264, 171-176 (2018)
Itoh A, Nonaka Y, Ogawa T, Nakamura T, Nishi N. Small leucine-rich repeat proteoglycans associated with mature insoluble elastin serve as binding sites for galectins. Biosci Biotechnol Biochem. 2017;81(11):2098-2104.

Uemura M, Imataki O, Uchida S, Nakayama-Imaohji H, Ohue Y, Matsuka H, Mori H, Dobashi H, Kuwahara T, Kadowaki N. Strain-specific transmission in an outbreak of ESBL-producing Enterobacteriaceae in the hematooncology care unit: a cohort study. BMC Infect Dis. 26, 2017
Ishijima N, Lee KI, Kuwahara T, Nakayama-Imaohji H, Yoneda S, Iguchi A, Ogura Y, Hayashi T, Ohnishi M, Iyoda S. Identification of a new virulent clade in Enterohemorrhagic Escherichia coli O26:H11/H- sequece type 29. Sci Rep. 43136, 2017.
Kino Yasuhiro, Haruyuki Nakayama-Imaohji, Masashi Fujita, Ayano Tada, Saori Yoneda, Kazuya Murakami, Masahito Hashimoto, Tetsya Hayashi, Katsuichiro Okazaki and Tomomi Kuwahara. Counterselection employing mutated pheS for markerless genetic deletion in Bacteroides species. Anaerobe 42:81-88, 2016.
Khaleque Hasibul, Haruyuki Nakayama-Imaohji, Masahito Hashimoto, Hisashi Yamasaki, Takaaki Ogawa, Junpei Waki, Ayano Tada, Soari Yoneda, Masaaki Tokuda, Minoru Miyake, Tomomi Kuwahara. D-Tagatose inhibits the growth and biofilm formation of Streptococcus mutans ,Mol Med Rep, 2016, in press.
Bernard KA, Pacheco AL, Loomer C, Burdz T, Wiebe D, Huynh C, Kaplen B, Olson AB, Cnockaert M, Eguchi H, Kuwahara T, Nakayama-Imaohji H, Shiota H, Boudewijns M, Van Hoecke F, Vandamme P.Corynebacterium lowii sp. nov. and Corynebacterium oculi sp. nov., derived from Human Clinical Disease and an Emended Description of Corynebacterium mastitidis. Int. J. Syst. Evol. Microbiol. 66, 2803-2812, 2016.
結膜嚢常在細菌叢．GANKA Ophthalmology, 2016, 157-165. 桑原知巳
腸内フローラに基づく腸内機能評価．日本静脈経腸栄養学会雑誌 2016, 1095-1098. 田中　彩, 下野隆一, 今大路治之, 鈴木基生, 桑原知巳
Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto M, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM,Altered cortical dynamics and cognitive function upon haploinsufficiency of the autism linked excitatory synaptic suppressor MDGA2.,Neuron 91, 1052-1068 (2016).
藤澤良秀、西山　成病態生理-交感神経- CKD 最新医学社, 倉林正彦企画, P66-71, 2016
西山　成アンジオテンシン?受容体拮抗薬腎と透析，80(4): 459-462, 2016
西山　成腎が体液調節を司る際の修飾因子ー心不全時に着目してー　神経体液性因子心腎連関を深め体液管理を極める文光堂, 猪又孝元編集, P48-51, 2016
西山　成 RASと糖尿病性腎症腎臓内科・泌尿器科,3（6）： 565-569, 2016
西山　成 ARBには本当に腎保護効果があるのか？Heart View, 20(10): 80-85, 2016
Takeshige Y, Fujisawa Y, Rahman A, Kittkulsuth W, Nakano D, Mori H, Masaki T, Ohmori K, Kohno M, Ogata H, Nishiyama A. A sodium-glucose co-transporter 2 inhibitor empagliflozin prevents abnormality of circadian rhythm of blood pressure in salt-treated obese rats. Hypertens Res. 2016 Jun;39(6):415-22..
Rahman A, Kittikulsuth W, Fujisawa Y, Sufiun A, Rafiq K, Hitomi H, Nakano D, Sohara E, Uchida S, Nishiyama A. Effects of diuretics on SGLT2 inhibitor-induced changes in blood pressure in obese rats suffering from the metabolic syndrome.J Hypertens, 2016 May;34(5):893-906.
Sato S, Qi W, Kawashima N, Nogo K, Hosono S, Nishiyama A, Wada K,b and Ishimaru I.Ultraminiature one-shot fourier-spectroscopic tomography.Optical Engineering, 55(2): 025106, 2016
Souma T, Nezu M, Nakano D, Yamazaki S, Hirano I, Sekine H, Dan T, Takeda K, Fong GH, Nishiyama A, Ito S, Miyata T, Yamamoto M, Suzuki N. Erythropoietin synthesis in renal myofibroblasts is restored by activation of hypoxia signaling J Am Soc Nephrol. 2016 Feb;27(2):428-38.
Nakano D and Nishiyama A.Multiphoton imaging of kidney pathophysiology . J Pharmacol Sci. 2016 Sep;132(1):1-5.
Ueno M, Chiba Y, Matsumoto K, Murakami R, Fujihara R, Kawauchi M, Miyanaka H, Nakagawa T, Blood-brain barrier damage in vascular dementia. Neuropathology, 36(2), (2016) 115-124
Ueno M, Chiba Y, Murakami R, Matsumoto K, Kawauchi M, Fujihara R, Kawauchi M, Blood-brain barrier and blood-cerebrospinal fluid barrier in normal and pathological conditions. Brain Tumor Pathol, 33(2), (2016) 89-96
Murakami R, Chiba Y, Tsuboi K, Matsumoto K, Kawauchi M, Fujihara R, Mashima M, Kanenishi K, Yamamoto T, Ueno M, Immunoreactivity of glucose transporter 8 is localized in the epithelial cells of the choroid plexus and in ependymal cells. Histochem Cell Biol, 146(2), (2016) 231-236
Fujihara R, Chiba Y, Nakagawa T, Nishi N, Murakami R, Matsumoto K, Kawauchi M, Yamamoto T, Ueno M. Albumin microvascular leakage in brains with diabetes mellitus. Microsc Res Tech, 79(9), (2016) 833-837
Mashima M, Chiba Y, Murakami R, Uemura N, Matsumoto K, Kawauchi M, Kanenishi K, Hata T, Ueno M. Glucose transporter 8 immunoreactivity in astrocytic and microglial cells in subependymal areas of human brains. Neurosci Lett, 636, (2017) 90-94
Yamaguchi F, Tsuchiya M, Shimamoto S, Fujimoto T, Tokumitsu H, Tokuda M, Kobayashi R.Oxidative Stress Impairs the Stimulatory Effect of S100 Proteins on Protein Phosphatase 5 Activity.Tohoku J Exp Med. 2016;240(1):67-78. doi: 10.1620/tjem.240.67.
D-Allose Inhibits Cancer Cell Growth by Reducing GLUT1 Expression.
Hormonal changes following a low-salt diet in patients with Me´nie`re's disease.
Deletion of Tricellulin Causes Progressive Hearing Loss Associated with Degeneration of Cochlear Hair Cells.
The difference in endolymphatic hydrostatic pressure elevation induced by isoproterenol between the ampulla and the cochlea
蝸牛におけるtricellulinの機能
Ion transport its regulation in the endolymphatic sac: suggestions for clinical aspects of Meniere's disease.
Hasan AU, Ohmori K, Hashimoto T, Kamitori K, Yamaguchi F, Konishi K, Noma T, Igarashi J, Yamashita T, Hirano K, Tokuda M, Minamino T, Nishiyama A, Kohno M. Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes. Biogerontology, 2017:18(1):55-68
Ohta KI, Suzuki S, Warita K, Kaji T, Kusaka T, Miki T. Prolonged maternal separation attenuates BDNF-ERK signaling correlated with spine formation in the hippocampus during early brain development. J Neurochem. 2017 (Epub ahead of print).
Hussain Z, Uyama T, Kawai K, Rahman IA, Tsuboi K, Araki N, Ueda N, Comparative analyses of isoforms of the calcium-independent phosphatidylethanolamine N-acyltransferase PLAAT-1 in humans and mice. J Lipid Res 57:2051-2060, 2016
Sakura Y, Tsuboi K, Uyama T, Zhang X, Taoka R, Sugimoto M, Kakehi Y, Ueda N A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells. Biochim Biophys Acta-Mol Cell Biol Lipids 1861:1951-1958, 2016
Rahman IAS, Tsuboi K, Hussain Z, Yamashita R, Okamoto Y, Uyama T, Yamazaki N, Tanaka T, Tokumura A, Ueda N, Calcium-dependent generation of N-acylethanolamines and lysophosphatidic acids by glycerophosphodiesterase GDE7. Biochim Biophys Acta-Mol Cell Biol Lipids 1861:1881-1892, 2016
Uyama T, Ueda N, Assay of NAT activity. Methods Mol Biol 1412, Endocannabinoid Signaling: Methods and Protocols (Maccarrone M, ed) Humana Press, 112-122, 2016 (ISBN: 978-1-4939-3537-6)
Tsuboi K, Ueda N, Assay of NAAA activity. Methods Mol Biol 1412, Endocannabinoid Signaling: Methods and Protocols (Maccarrone M, ed) Humana Press, 137-148, 2016 (ISBN: 978-1-4939-3537-6)
坪井一人，N-アシルエタノールアミンとリゾホスファチジン酸の生合成に関わる新規リゾホスホリパーゼD型酵素．生化学 88:240-243, 2016
宇山徹，渡邊政博, 坪井一人, 上田夏生，明らかになり始めた新規脂質代謝酵素群phospholipase A/acyltransferase (PLAAT) familyの生理機能．ビタミン 90:379-389, 2016
Hayashida Y, Ikeda Y, Sawada K, Kawai K, Kato T, Kakehi Y, Araki N., Invention of a novel photodynamic therapy for tumors using a photosensitizing PI3K inhibitor., Int J Cancer. 2016 Aug 1;139(3):700-11.
Lu Y, Cao L, Egami Y, Kawai K, Araki N., Cofilin contributes to phagocytosis of IgG-opsonized particles but not non-opsonized particles in RAW264 macrophages., Microscopy (Oxf). 2016 Jun;65(3):233-42.
Nakakita S, Itoh A, Nakakita Y, Nonaka Y, Ogawa T, Nakamura T, Nishi N. ,Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9. J Biol Chem. 2016;291(2):968-79.

Egami Y, Fujii M, Kawai K, Ishikawa Y, Fukuda M, Araki N., Activation-Inactivation Cycling of Rab35 and ARF6 Is Required for Phagocytosis of Zymosan in RAW264 Macrophages., J Immunol Res. 2015;2015:429439.
Antidiabetic drug metformin inhibits esophageal adenocarcinoma cell proliferation in vitro and in vivo.Fujihara S, Kato K, Morishita A, Iwama H, Nishioka T, Chiyo T, Nishiyama N, Miyoshi H, Kobayashi M, Kobara H, Mori H, Okano K, Suzuki Y, Masaki T.Int J Oncol　46: 2172-2180, 2015
Galectin-9 suppresses the growth of hepatocellular carcinoma via apoptosis in vitro and in vivo.Fujita K, Iwama H, Sakamoto T, Okura R, Kobayashi K, Takano J, Katsura A, Tatsuta M, Maeda E, Mimura S, Nomura T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Yamana Y, Himoto T, Okano K, Suzuki Y, Niki T, Hirashima M, Masaki T.Int J Oncol　46: 2419-2430, 2015
MicroRNA profiles in cisplatin-induced apoptosis of hepatocellular carcinoma cells.Miyata M, Morishita A, Sakamoto T, Katsura A, Kato K, Nishioka T, Toyota Y, Fujita K, Maeda E, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Fujiwara S, Nishiyama N, Iwama H, Himoto T, Hirashima1 M, Masaki T.Int J Oncol　47: 535-542, 2015
Galectin-9 suppresses cholangiocarcinoma cell proliferation by inducing apoptosis but not cell cycle arrest.Kobayashi K, Morishita A, Iwama H, Fujita K, Okura R, Fujihara S, Yamashita T, Fujimori T, Kato K, Kamada H, Niki T, Hirashima M, Okano K, Suzuki Y, Masaki T.Oncol Rep　34: 1761-1770, 2015
Mechanism of gemcitabine-induced suppression of human cholangiocellular carcinoma cell growth.Toyota Y, Iwama H, Kato K, Tani J, Katsura A, Miyata M,Fujiwara S, Fujita K, Sakamoto T, Fujimori T, Okura R, Kobayashi K, Tadokoro T, Mimura S, Nomura T, Miyoshi H, Morishita A, Kamada H, Yoneyama H, Okano K,Suzuki Y, Masaki T.Int J Oncol　47: 1293-1302, 2015
Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies.Fujimori T, Kato K, Fujihara S, Iwama H, Yamashita T, Kobayashi K, Kamada H, Morishita A, Kobara H, Mori H, Okano K, Suzuki Y, Masaki T.Oncol Rep　34: 2987-2996, 2015
The anti-diabetic drug metformin inhibits pancreatic cancer cell proliferation in vitro and in vivo: Study of the microRNAs associated with the antitumor effect of metformin.Kato K, Iwama H, Yamashita T, Kobayashi K, Fujihara S, Fujimori T, Kamada H, Kobara H, Masaki T.Oncol Rep　35: 1582-1592, 2015
Evaluation of in vivo efficacy of radiofrequency ablation with D-sorbitol in animal liver.Morishita A, Sakamoto T, Kobara H, Tadokoro T, Ohura K, Fujita K, Tani J, Miyoshi H, Yoneyama H, Himoto T, Masaki T.Mol Clin Oncol　4: 183-186, 2016
Galectin-9 suppresses the proliferation of gastric cancer cells in vitro.Takano J, Morishita A, Fujihara S, Iwama H, Kokado F, Fujikawa K, Fujita K, Chiyo T, Tadokoro T, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Kobara H, Mori H, Niki T, Hirashima M, Masaki T.Oncol Rep　35: 851-860, 2016
Galectin-9: An anticancer molecule for gallbladder carcinoma.Tadokoro T, Morishita A,Fujihara S, Iwama H, Niki T, Fujita K, Akashi E, Mimura S, Oura K, Sakamoto T, Nomura T, Tani J, Miyoshi H, Yoneyama H, Himoto T, Hirashima M, Masaki T.Int J oncol　48: 1165-1174, 2016
The anti-diabetic drug metformin inhibits pancreatic cancer cell proliferation in vitro and in vivo: Study of the microRNAs associated with the antitumor effect of metformin.Kato K, Iwama H, Yamashita T, Kobayashi K, Fujihara S, Fujimori T, Kamada H, Kobara H, Masaki T.Oncol Rep　35: 1582-1592, 2016
Prox1 expression in the endolymphatic sac revealed by whole-mount fluorescent imaging of Prox1-GFP transgenic mice.
D-Allose Inhibits Cancer Cell Growth by Reducing GLUT1 Expression.
Deletion of Tricellulin Causes Progressive Hearing Loss Associated with Degeneration of Cochlear Hair Cells.
Effect of dipeptidyl peptidase-4 inhibition on circadian blood pressure during the development of salt-dependent hypertension in rats.　Hypertens Res. 2015 Apr;38(4):237-243.
Urinary angiotensinogen could be a prognostic marker of renoprotective effects of alogliptin in patients with type 2 diabetes.J Diabetes Res. 2015;2015:517472.
Chelation of dietary iron prevents iron accumulation and macrophage infiltration in the type I diabetic kidney.Eur J Pharmacol. 2015 Jun 5;756:85-91.
Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial.Clin Exp Nephrol. 2015 Dec;19(6):1098-106.
Reduction of tubular flow rate as a mechanism of oliguria in the early phase of endotoxemia revealed by intravital imaging.J Am Soc Nephrol. 2015 Dec;26(12):3035-44.
Role of the renal sympathetic nerve in renal glucose metabolism during the development of type 2 diabetes in rats.Diabetologia. 2015 Dec;58(12):2885-2898.
Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats. Clin Exp Pharmacol Physiol. 2015 Nov;42(11):1178-1188.
Immunoreactive insulin in diabetes mellitus patient sera detected by ultrasensitive ELISA with thio-NAD cycling.Ito E, Kaneda M, Kodama H, Morikawa M, Tai M, Aoki K, Watabe S, Nakaishi K, Hashida S, Tada S, Kuroda N, Imachi H, Murao K, Yamashita M, Yoshimura T, Miura T.Biotechniques. 2015 Dec 1;59(6):359, 361-7
Roles of lipoprotein receptors in the entry of hepatitis C virus.Lyu J, Imachi H, Fukunaga K, Yoshimoto T, Zhang H, Murao K.World J Hepatol. 2015 Oct 28;7(24):2535-42.
Tada A, Nakayama-Imaohji H, Yamasaki H, Hasibul K, Yoneda S, Uchida K, Nariya H, Suzuki M, Miyake M, Kuwahara T.Cleansing effect of acidic L-arginine on human oral biofilm. BMC Oral Health, Vol.16, (2016)40
Nakayama-Imaohji H, Hirota K, Yamasaki H, Yoneda S, Nariya H, Suzuki M, Secher T, Miyake Y, Oswald E, Hayashi T, Kuwahara T. DNA inversion regulates outer membrane vesicle production in Bacteroides fragilis. PLoS One, Vol.12, No.2(2016) e0148887
Yamaoka H, Nakayama-Imaohji H, Horiuchi I, Yamasaki H, Nagao T, Fujita Y, Maeda H, Goda H, Kuwahara T. Tetramethylbenzidine method for minitoring the free available chlorine and microbicidal activity of chlorite-based sanitizers under organic-matter-rich environments. Lett. Appl. Microbiol., Vol.62, No.1(2016) 47-54
Uyama T, Ueda N, Assay of NAT activity. Methods Mol Biol 1412, Endocannabinoid Signaling: Methods and Protocols (Maccarrone M, ed) Humana Press, 112-122, 2016 (ISBN: 978-1-4939-3537-6)
Tsuboi K, Ueda N, Assay of NAAA activity. Methods Mol Biol 1412, Endocannabinoid Signaling: Methods and Protocols (Maccarrone M, ed) Humana Press, 137-148, 2016 (ISBN: 978-1-4939-3537-6)
坪井一人，N-アシルエタノールアミンとリゾホスファチジン酸の生合成に関わる新規リゾホスホリパーゼD型酵素．生化学 88:240-243, 2016
Uyama T, Kawai K, Kono N, Watanabe M, Tsuboi K, Inoue T, Araki N, Arai H, Ueda N, Interaction of phospholipase A/acyltransferase-3 with Pex19p: a possible involvement in the downregulation of peroxisomes. J Biol Chem 290:17520-17534, 201
Tsuboi K, Okamoto Y, Rahman IAS, Uyama T, Inoue T, Tokumura A, Ueda N, Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis. Biochim Biophys Acta - Mol Cell Biol Lipids 1851:537-548, 2015
宇山徹，ホスホリパーゼA／アシルトランスフェラーゼ-3を介したペルオキシソームの制御機構．生化学 87:633-635, 2015
宇山徹，上田夏生，新規脂質代謝酵素群 PLAAT ファミリータンパク質の生理機能解析．BIO Clinica 30:89-95, 2015
坪井一人，上田夏生，エンドカンナビノイド．疾患モデルの作製と利用－脂質代謝異常と関連疾患<<下巻>>（尾池雄一，佐々木雄彦，村上　誠，矢作直也編）エル・アイ・シー社，東京，236-248, 2015
S. Kamitori and H. Yoshida, Structure-Function Relationship of Bacterial SH3 Domains. Springer; SH Domains -Structure, Mechanisms and Applications- (2015), 71-90 (ISBN: 978-3-319-20097-2)
Y. Terami, H. Yoshida, K. Uechi, K. Morimoto, G. Takata and S. Kamitori, Essentiality of tetramer formation of Cellulomonas parahominis L-ribose isomerase involved in novel L-ribose metabolic pathway. Appl Microbiol Biotechnol. , 99(15), 6303-6313, (2015)
H. Yoshida, G. Sakai, K. Mori, K. Kojima, S. Kamitori and K. Sode, Structural analysis of fungus-derived FAD glucose dehydrogenase, Sci. Rep., 5, 13498, (2015)

Ueno M, Uchida K, Saito W, Matsushita O, Yogoro M, Nishi N, Ogura T, Hattori S, Inoue G, Tanaka K, Takahira N, Takaso M. Acceleration of bone union after structural bone grafts with a collagen-binding basic fibroblast growth factor anchored-collagen sheet for critical-size bone defects. Biomed Mater. 2014 Jun;9(3):035014.
Madireddi S, Eun SY, Lee SW, Nem?ovi?ova´ I, Mehta AK, Zajonc DM, Nishi N, Niki T, Hirashima M, Croft M. Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies. J Exp Med. 2014 Jun 30;211(7):1433-48.
Fukata Y, Itoh A, Nonaka Y, Ogawa T, Nakamura T, Matsushita O, Nishi N. Direct cytocidal effect of galectin-9 localized on collagen matrices on human immune cell lines. Biochim Biophys Acta. 2014 Jun;1840(6):1892-901.
Uchida K, Matsushita O, Naruse K, Mima T, Nishi N, Hattori S, Ogura T, Inoue G, Tanaka K, Takaso M. Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase. J Biomed Mater Res A. 2014 Jun;102(6):1737-43.
Saito W, Uchida K, Ueno M, Matsushita O, Inoue G, Nishi N, Ogura T, Hattori S, Fujimaki H, Tanaka K, Takaso M. Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase. J Biomed Mater Res A. 2014 Sep;102(9):3049-55.
白井　僚;　岡本　研正;　服部　哲郎;平田　裕子;　山口　文徳;　徳田　雅明; 高効率LEDによる光照射とビリルビン添加による白血病細胞増殖抑制電気学会論文誌 Vol. 134 No. 11 (2014.11.1)
Akram Hossain1,2,*, Fuminori Yamaguchi1, Kayoko Hirose1, Toru Matsunaga3, Li Sui1, Yuko Hirata1, Chisato Noguchi1, Ayako Katagi1, Kazuyo Kamitori1, Youyi Dong1, Ikuko Tsukamoto4, Masaaki Tokuda1 Rare sugar D-psicose prevents progression and development of diabetes in T2DM model Otsuka-Long-Evans-Tokushima Fatty rats Drug Design, Development and Therapy Vol.9(2015.1.17) 525-35
出口一志、浦井由光、正木　勉,傍腫瘍性壊死性脊髄症,神経症候群（第2版）－その他の神経疾患を含めて－,日本臨牀社　別冊日本臨牀　新領域別症候群シリーズ,?27(2014)762-766
峠　哲男、高田忠幸,第4章　特異的神経感染症　神経梅毒,新しい診断と治療のABC82／神経7　神経関連感染症　2014年最新医学　別冊,最新医学社,(2014)131-136
樋本尚志、正木　勉,亜鉛代謝,Hepatology Practice 3　Ｃ型肝炎の診療を極める～基本から最前線まで～,文光堂,(2014)280-286
米山弘人、正木　勉,?治療編　Ｉ．肝細胞癌以外の肝癌の治療内科的治療Hepatology Practice 第5巻,肝癌の診療を極める～基本から最前線まで～,文光堂,(2014)280-286
森　宏仁、小原英幹、西山典子、藤原新太郎、松永多恵、綾木麻紀、谷内田達夫、正木　勉,手技の解説内視鏡的穿孔部・瘻孔部閉鎖術（ＯＴＳＣシステム）,臨牀消化器内科,日本メディカルセンター,29(9):(2014)1288-1294
森　宏仁,内視鏡的全層切除術(EFTR)－超低侵襲内視鏡手術の最先端－,医学のあゆみ,医歯薬出版株式会社,250(10):(2014)935-941
出口一志, 痛みレジデントのためのパーキンソン病ハンドブック,中外医学社,(2014)84-92
Liu G, Hitomi H, Rahman A, Nakano D, Mori H, Masaki T, Ma H, Iwamoto T, Kobori H, Nishiyama A.High sodium augments angiotensin II-induced vascular smooth muscle cell proliferation through the ERK 1/2-dependent pathway.Hypertens Res､37(2014)13-18
Mori H, Rafiq K, Kobara H, Tsushimi T, Fujihara S, Nishiyama N, Matsunaga T, Ayaki M, Yachida T, Tani J, Miyoshi H, Masaki T.Development of pure endoscopic full-thickness resection with mechanical countertraction and double-armed bar suturing systems.Gastrointest Endosc,79(2014) 24-25
Rafiq K, Fan Y, Sherajee J, Takahashi Y, Matsuura J, Hase N, Mori H, Nakano D, Kobara H, Hitomi H, Masaki T, Urata H, Nishiyama A.Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice.Int J Med Sci,11(2014)222-225
Kojima R, Ohno T, Iikura M, Niki T, Hirashima M, Iwaya K, Tsuda H, Nonoyama S, Matsuda A, Saito H, Matsumoto K, Nakae S.Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cell Line.PLoS One,9(2014)e86106
Izuishi K, Yamamoto Y, Mori H, Kameyama R, Fujihara S, Masaki T, Suzuki Y.Molecular mechanisms of [18F]fluorodeoxyglucose accumulation in liver cancer.Oncol Rep,31(2014) 701-706
Mori H, Kobara H, Fujihara S, Nishiyama N, Rafiq K, Oryu M, Fujiwara M, Suzuki Y, Masaki T.Feasibility of pure EFTR using an innovative new endoscopic suturing device: the Double-arm-bar Suturing System (with video).Surg Endosc,28(2014)683-690
Mori H, Kobara H, Fujihara S, Nishiyama N, Ayaki M, Yachida T, Okano K, Suzuki Y, Masaki T.Pure endoscopic full-thickness resection with peritoneoscopy and omentectomy.J Digest Dis,15(2014) 96-101
Miyoshi H, Morishita A, Tani J, Sakamoto T, Fujita K, Katsura A, Tatsuta M, Nomura T, Yoneyama H, Iwama H, Suzuki Y, Masaki T.Expression profiles of 507 proteins from a biotin label-based antibody array in human colorectal cancer.Oncol Rep,31(2014):1277-1281
Kakinoki K, Okano K, Oshima M, Suto H, Kashiwagi H, Yamamoto N, Akamoto S, Fujiwara M, Yachida S, Takama T, Hagiike M, Usuki H, Kamata H, Masaki T, Suzuki Y.A Novel Triple Secured Technique for Pancreatic Reconstruction Following Pancreaticoduodenectomy for a Soft Pancreas.Hepato-Gastroenterol,61(130): (2014),469-474
Vega-Carrascal I, Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K, Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG.Galectin-9 signaling through TIM-3 is involved in neutrophil-mediated Gram-negative bacterial killing: an effect abrogated within the cystic fibrosis lung.J Immunol,192(2014) 2418-2431,
樋本尚志、野村貴子、谷　丈二、三好久昭、森下朝洋、米山弘人、犬飼道雄、合田文則、正木勉,C型慢性肝疾患患者における糖および脂質代謝に及ぼす微量元素の役割消化と吸収,36(2'13): (2014)248-252
Zhang Q, Luan H, Wang L, He F, Zhou H, Xu X, Li X, Xu Q, Niki T, Hirashima M, Xu G, Lv Y, Yuan J.Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.Am J Physiol Renal Physiol,306(2014) F822-F832
Katoh S, Ikeda M, Shimizu H, Mouri K, Obase Y, Kobashi Y, Fukushima K, Hirashima M, Oka M.Increased levels of plasma galectin-9 in patients with influenza virus infection.Tohoku J Exp Med,232(2014) 263-267
三好久昭、加藤清仁、小林三善、岩間久和、正木　勉,,抗糖尿病薬メトホルミンの肝癌細胞抑制メカニズム,消化器内科,58(5):(2014) 688-696,
Watanabe S, Morishita A, Deguchi A, Nakai S, Sakamoto T, Fujita K, Maeda E, Nomura T, Tani J, Miyoshi H, Yoneyama H, Fujihara S, Kobara H, Mori H, Himoto T, Masaki T.Ethanol injection therapy for small hepatocellular carcinomas located beneath a large vessel using a curved percutaneous ethanol injection therapy needle.Oncol Lett,7(2014) 1831-1834
Madireddi S, Eun SY, Lee SW, Nem?ovi?ova´ I, Mehta AK, Zajonc DM, Nishi N, Niki T, Hirashima M, Croft M.Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.J Exp Med,211(2014): 1433-1448
Miyoshi H, Kato K, Iwama H, Maeda E, Sakamoto T, Fujita K, Toyota Y, Tani J, Nomura T, Mimura S, Kobayashi M, Morishita A, Kobara H, Mori H, Yoneyama H, Deguchi A, Himoto T, Kurokohchi K, Okano K, Suzuki Y, Murao K, Masaki T.Effect of the anti-diabetic drug metformin in hepatocellular carcinoma in vitro and in vivo.Int J Oncol,45(1): (2014)322-332
Kobara H, Mori H, Rafiq K, Matsunaga T, Fujihara S, Nishiyama N, Ayaki M, Yachida T, Tani J, Miyoshi H, Kato K, Kamada H, Yoneyama H, Morishita A, Tsutsui K, Iwama H, Haba R, Masaki T.Evaluation of gastric submucosal tumors using endoscopically visualized features with submucosal endoscopy.Oncol Lett,8(1): (2014)161-168
Tandon R, Chew GM, Byron MM, Borrow P, Niki T, Hirashima M, Barbour JD, Norris PJ, Lanteri MC, Martin JN, Deeks SG, Ndhlovu LC.Galectin-9 is rapidly released during acute HIV-1 infection and remains sustained at high levels despite viral suppression even in elite controllers.AIDS Res Hum Retrov,30(2014)654-664
Okano K, Oshima M, Yachida S, Kushida Y, Kato K, Kamada H, Wato M, Nishihira T, Fukuda Y, Maeba T, Inoue H, Masaki T, Suzuki Y.Factors predicting survival and pathological subtype in patients with ampullary adenocarcinoma.J Surg Oncol,110(2014):156-162
Mori H, Kobara H, Rafiq K, Fujihara S, Nishiyama N, Masaki T.Balloon-Armed Mechanical Counter Traction and Double-Armed Bar Suturing Systems for Pure Endoscopic Full-thickness Resection.Gastroenterology,147(2):(2014) 278-280
Mimura S, Iwama H, Kato K, Nomura K, Kobayashi M, Yoneyama H, Miyoshi H, Tani J, Morishita A, Himoto T, Deguchi A, Nomura T, Sakamoto T, Fujita K, Maeda E, Izuishi K, Okano K, Suzuki Y, Masaki T.Profile of microRNAs associated with aging in rat liver.Int J Mol Med,34(2014) 1065-1072
Wu C, Thalhamer T, Franca RF, Xiao S, Wang C, Hotta C1, Zhu C, Hirashima M, Anderson AC, Kuchroo VK.Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells.Immunity,41(2014) 270-282
Kitada K, Nakano D, Ohsaki H, Hitomi H, Minamino T, Yatabe J, Felder RA, Mori H, Masaki T, Kobori H, Nishiyama A.Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy.J Diabetes Complicat,28(5): (2014)604-611
Rafiq K, Nishiyama A, Konishi Y, Morikawa T, Kitabayashi C, Kohno M, Masaki T, Mori H, Kobori H, Imanishi M.Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats.PLoS One,9(9):(2014) e107853
Mori H, Kobara H, Tsushimi T, Fujihara S, Nishiyama N, Matsunaga T, Ayaki M, Yachida T, Tani J, Miyoshi H, Morishita A, Masaki T.Reduction effect of bacterial counts by preoperative saline lavage of the stomach in performing laparoscopic and endoscopic cooperative surgery.World J Gastroentero,20(42):(2014) 15763-15770
Masaki N, Sugiyama M, Shimada N, Tanaka Y, Nakamuta M, Izumi N, Watanabe S, Tsubota A, Komatsu M, Masaki T, Enomoto N, Yoneda M, Murata K, Ito K, Koike K, Mizokami M.Pretreatment prediction of the outcome of response-guided peginterferon-α and ribavirin therapy for chronic hepatitis C.J Gastroenterol Hepatol,29(12):(2014)1996-2005
Mori H, Kobara H, Rafiq K, Masaki T.Local steroid injection prevent deformity and stenosis of stomach after large endoscopic submucosal dissection.Am J Digest Dis ,1(2):(2014)136-142
Sasaki T, Isayama H, Nakai Y, Ito Y, Yasuda I, Toda N, Yagioka H, Matsubara S, Hanada K, Maguchi H, Kamada H, Hasebe O, Mukai T, Okabe Y, Maetani I, Koike K.Treatment outcomes of chemotherapy between unresectable and recurrent biliary tract cancer.World J Gastroentero,20(48): (2014)18452-18457
Yoshida S, Ikenaga N, Liu SB, Peng ZW, Chung J, Sverdlov DY, Miyamoto M, Kim YO, Ogawa S, Arch RH, Schuppan D, Popov Y.Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice.Gastroenterology,147(6): (2014)1378-1392,
杵川文彦、松田和也、大山知代、井上利彦、高畠理恵、木田裕子、中尾克之、徳田道昭、正木　勉,糖尿病患者の腹部症状とQOLとの関連,消化管の臨床,19(2014)
Himoto T, Nishioka M, Masaki T.Relationship between Autoimmunity and Cancer or Metabolic Abnormality in Liver Diseases.The Open Autoimmunity Journal,6(2014) 1-8
Kobara H, Mori H, Rafiq K, Fujihara S, Nishiyama N, Ayaki M, Yachida T, Matsunaga T, Tani J, Miyoshi H, Yoneyama H, Morishita A, Oryu M, Iwama H, Masaki T.Submucosal tunneling techniques: current perspectives.Clin Exp Gastroenterol,5(2014) 67-74
Fujihara S, Mori H, Kobara H, Nishiyama N, Matsunaga T, Ayaki M, Yachida T, Morishita A, Izuishi K, Masaki T.Current innovations in endoscopic therapy for the management of colorectal cancer: From endoscopic submucosal dissection (ESD) to endoscopic full-thickness resection (EFTR).Biomed Res Int,2014:(2014): 925058
Morishita A, Gong J, Masaki T.Targeting receptor tyrosine kinases in gastric cancer.World J Gastroentero,20(16):(2014)4536-4545
出口一志,脳神経内科領域におけるめまいの診療,ラウンドミラー,32(2014)5-8
池田和代、長根百合子、出口一志、槍澤公明,重症筋無力症におけるIVIg治療,神経内科,科学評論社,82(3):(2015)254-258
森　宏仁,Laparoscopy and endoscopy cooperative surgery(LECS)における軟性内視鏡側の清潔操作,イラストと写真で見る内視鏡医と外科医のコラボレーション手術,株式会社メジカルビュー社,(2015)162-165
Mori H, Kobara H, Fujihara S, Nishiyama N, Ayagi M, Matsunaga T, Yachida T, Masaki T.Establishment of the hybrid endoscopic full-thickness resection of gastric gastrointestinal stromal tumors.Mol Clin Oncol, 3(2015) 18-22
Kobara H, Mori H, Rafiq K, Fujihara S, Nishiyama N, Chiyo T, Matsunaga T, Ayaki M, Yachida T, Kato K, Kamada H, Fujita K, Morishita A, Oryu M, Tsusui K, Iwama H, Kushida Y, Haba R, Masaki T.Analysis of the amount of tissue sample necessary for mitotic count and Ki-67 index in gastrointestinal stromal tumor sampling.Oncol Rep,33(2015): 215-222
Kobara H, Mori H, Kazi R, Fujihara H, Nishiyama N, Morishita A, Goda Y, Kanenishi K, Hata T, Masaki T.Application of endoscopic hemostatic forceps for uterine cervical bleeding.Gastrointest Endosc,81(1):(2015) :234-235
Mori H, Takao H, Kobara H, Nishiyama N, Fujihara S, Matsunaga T, Ayaki M, Masaki T.Precise tumor size measurement under constant pressure by novel real-time micro-electro-mechanical-system hood for proper treatment (with videos).Surg Endosc,29(1):(2015): 212-219
Sufiun A, Rafiq K, Fujisawa Y, Rahman A, Mori H, Nakano D, Kobori H, Ohmori K, Masaki T, Kohno M, Nishiyama A.Effect of the dipeptidyl peptidase-4 inhibition on circadian blood pressure during the development of salt-dependent hypertension in rats.Hypertens Res,2015: (2015)1-7
Himoto T, Nomura T, Tani J, Miyoshi H, Morishita A, Yoneyama H, Haba R, Masugata H, Masaki T.Exacerbation of Insulin Resistance and Hepatic Steatosis Deriving from Zinc Deficiency in Patients with HCV-Related Chronic Liver Disease.Biol Trace Elem Res,163:(2015) 81-88
Morishita A, Masaki T.miRNA in hepatocellular carcinoma.Hepatol Res,45(2015) 128-141
Suzuki S, Murotomi K, Nakajima Y, Kawai K, Ohta K, Warita K, Miki T, and Takeuchi Y. Development of an artificial calcium-dependent transcription factor to detect sustained intracellular calcium elevation. ACS synthetic biology 2014 Oct 17;3(10):717-22.
Ohta K, Miki T, Warita K, Suzuki S, Kusaka T, Yakura T, Liu JQ, Tamai M, Takeuchi Y. Prolonged maternal separation disturbs the serotonergic system during early brain development. Int J Dev Neurosci. 2014; 33: 15-21.
宇山徹，上田夏生，アナンダミドと関連N-アシルエタノールアミン．医学のあゆみ 248:1003-1008, 2014
Rahman IAS, Tsuboi K, Uyama T, Ueda N, New players in the fatty acyl ethanolamide metabolism. Pharmacol Res 86:1-10, 2014
Ueda N, Tsuboi K, Uyama T, CHAPTER 8 Metabolic Enzymes for Endocannabinoids and Endocannabinoid-Like Mediators. The Endocannabinoidome: The World of Endocannabinoids and Related Mediators (Di Marzo V, Wang J, eds) Elsevier, pp. 111-135, 2015 (ISBN: 978-0-12-420126-2)
Maekawa, M., Terasaka, S., Mochizuki, Y., Kawai, K., Ikeda, Y., Araki, N., Skolnik, E. Y., Taguchi, T., and Arai, H.: Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Proc. Natl. Acad. Sci. U. S. A. 111, E978－987 (2014). doi:10.1073/pnas.1311029111.
Kato, T., Kawai, K., Egami, Y. Kakehi, Y., Araki, N.:　Rac1-dependent lamellipodial motility in prostate cancer PC-3 cells revealed by optogenetic control of Rac1 activity PLoS One 9, e97749 (p.1-9) 2014, doi: 10.1371/journal.pone.0097749
Kanagawa, M., Lu, Z., Ito, C., Matsuda, C., Miyake, K., Toda, T.: Contribution of dysferlin deficiency to skeletal muscle pathology in asymptomatic and severe dystroglycanopathy models: generation of a new model for Fukuyama congenital muscular dystrophy. PLoS One 9, e106721. (2014) doi: 10.1371/journal.pone.0106721.
Egami, Y., Taguchi, T., Maekawa, M., Arai, H., and Araki, N.: Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation. Front. Physiol. 5, article 374 (p.1-11) (2014) doi:10.3389/fphys.2014.00374.
H. Yoshida, A. Yoshihara, M. Teraoka, Y. Terami, G. Takata, K. Izumori and S. Kamitori, X-ray structure of a novel L-ribose isomerase acting on a non-natural sugar L-ribose as its ideal substrate. FEBS J. , 281(14), 3150-3164, (2014)
Y. Nonaka, T. Ogawa, H. Yoshida, H. Shoji, N. Nishi, S. Kamitori, T. Nakamura, Crystal structure of a　Xenopus laevis skin proto-type galectin,close to but distinct from galectin-1. Glycobiology, Vol.25, No.7, (2015) 792-803
Antimicrobial activity and stability of weakly acidified chlorous acid water. Biocontrol Sci., 2015, 43-51. Horiuchi I, Kawata H, Nagao T, Imaohji H, Murakami K, Kino Y, Yamasaki H, Koyama AH, Fujita Y, Goda H, Kuwahara T.
Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. J Microbiol Methods, 2014, 174-179, Tagawa J, Inoue T, Naito M, Sato K, Kuwahara T, Nakayama M, Nakayama K, Yamashiro T, Ohara N.
Achromobacter buckle infection diagnosed by a 16S rDNA clone library analysis: a case report. BMC ophthalmol., 2014, 142, Hotta F, Eguchi H, Naito T, Mitamura Y, Kusujima K, Kuwahara T.
X-ray structure of a novel endolysin encoded by episomal phage phiSM101 of Clostridium perfringens. Mol. Microbiol., 2014, 326-337. Tamai E, Yoshida H, Sekiya H, Nariya H, Miyata S, Okabe A, Kuwahara T, Miaki J, Kamitori S.
Inhibition by caffeic acid of the influenza A virus multiplication in vitro. Int. J. Mol..Med., 2014, 1020-1024. Utsunomiya H, Ichinose M, Ikeda K, Uozaki M, Morishita J, Kuwahara T, Koyama AH, Yamasaki H.
Nishioka S, Nakano D, Kitada K, Sofue T, Ohsaki H, Moriwaki K, Hara T, Ohmori K, Kohno M, Nishiyama A.The cyclin-dependent kinase inhibitor p21 is essential for the beneficial effects of renal ischemic preconditioning on renal ischemia-reperfusion injury in mice.Kidney Int. 85: 871-879, 2014
Kuwabara T, Mori K, Kasahara M, Yokoi H, Imamaki H, Ishii A, Koga K, Sugawara A, Yasuno S, Ueshima K, Morikawa T, Konishi Y, Imanishi M, Nishiyama A, Nakao K, Mukoyama M.Predictive significance of kidney myeloid related protein 8 expression in patients with obesity- or type 2 diabetes-associated kidney diseases.PLoS ONE. 9(2): e88942, 2014 Feb
Kitada K, Nakano D, Ohsaki H, Hitomi H, Minamino T, Yatabe J, Felder RA, Mori H, Masaki T, Kobori H, Nishiyama A.Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathyJ Diabetes Complicat.28(5): 604-611,2014 Oct
Rafiq K, Nishiyama A, Konishi Y, Morikawa T, Kitabayashi C, Kohno M, Masaki T, Mori H, Kobori H, Imanishi M. Regression of glomerular and tubulointerstitial injuries by dietary salt reduction with combination therapy of angiotensin II receptor blocker and calcium channel blocker in Dahl salt-sensitive rats. PLoS ONE9(9): e107853, 2014 Sep
Cystic fibrosis transmembrane conductance regulator in the endolymphatic sac of the rat
特集１　難聴研究の新展開　内リンパ嚢の水・イオン輸送の分子機構
Effects of D-allose in combination with docetaxel in human head and neck cancer cells
ラット内リンパ嚢におけるcystic fibrosis transmembrane conductance regulatorの発現
マウス内リンパ嚢上皮細胞におけるProx1の発現

Igarashi J, Hashimoto T, Shoji K, Yoneda K, Tsukamoto I, Moriue T, Kubota Y and Kosaka H. Dexamethasone Induces Caveolin-1 In Vascular Endothelial Cells: implications for attenuated responses to VEGF. Am. J. Physiol. (Cell Physiology) 304(8): C790-C800, 2013.
Moriue T, Igarashi J, Yoneda K, Hashimoto T, Nakai K, Kosaka H and Kubota Y. Sphingosine 1-phosphate attenuates peroxide-induced apoptosis in HaCaT cells cultured in vitro. Clinical and Experimental Dermatology. 38(6) 638-645, 2013.
Valsartan ameliorates the constitutive adipokine expression pattern in mature adipocytes: a role for inverse agonism of the angiotensin II type 1 receptor in obesity., Arif U H, Ohmori K, Hashimoto Tその他7名, Hypertens Res. 37(7):621-628. 2014
Mifepristone Promotes Adiponectin Production and Improves Insulin Sensitivity in a Mouse Model of Diet-Induced-Obesity, Hashimoto T, Igarashi J その他６名, PLoS One. 8(11):e79724. 2013
Dexamethasone induces caveolin-1 in vascular endothelial cells: implications for attenuated responses to VEGF. Igarashi J; Hashimoto T その他６名, Am J Physiol Cell Physiol. 304(8):C790-80, 2013
Tenkumo K, Hirooka K, Sherajee SJ, Nakamura T, Itano T, Nitta E, Fujita T, Nishiyama A, Shiraga F. Effect of the renin inhibitor aliskiren against retinal ischemia-reperfusion injury. Exp Eye Res. 2014;122:110-8.
Omori C, Kaneko M, Nakajima E, Akatsu H, Waragai M, Maeda M, Morishima-Kawashima M, Saito Y, Nakaya T, Taru H, Yamamoto T, Asada T, Hata S, Suzuki T, Increased levels of plasma p3-Alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer's disease. J Alzheimers Dis. 2014;39(4):861-70. doi: 10.3233/JAD-131610.
Lu F, Nakamura T, Toyoshima T, Liu Y, Shinomiya A, Hirooka K, Okabe N, Miyamoto O, Tamiya T, Keep RF, Itano T. Neuroprotection of granulocyte colony-stimulating factor during the acute phase of transient forebrain ischemia in gerbils. Brain Res. 2014 Feb 22;1548:49-55.
Liu Y, Nakamura T, Toyoshima T, Lu F, Sumitani K, Shinomiya A, Keep RF, Yamamoto T, Tamiya T, Itano T. Ameliorative effects of yokukansan on behavioral deficits in a gerbil model of global cerebral ischemia. Brain Res. 2014 Jan 16;1543:300-7.
Shinomiya A, Miyake K, Okada M, Nakamura T, Kawai N, Kushida Y, Haba R, Kudomi N, Tokuda M, Tamiya T. 3'-Deoxy-3'-[(18)F]-fluorothymidine ([(18)F]-FLT) transport in newly diagnosed glioma: correlation with nucleoside transporter expression, vascularization, and blood-brain barrier permeability. Brain Tumor Pathol. 2013 Oct;30(4):215-23.
Nitta E, Hirooka K, Tenkumo K, Fujita T, Nishiyama A, Nakamura T, Itano T, Shiraga F. Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma. Cell Death Dis. 2013 Jul 4;4:e711.
Gao D, Kawai N, Nakamura T, Lu F, Fei Z, Tamiya T. Anti-inflammatory effect of D-allose in cerebral ischemia/reperfusion injury in rats. Neurol Med Chir (Tokyo). 2013;53(6):365-74.
Piao Y, Kimura A, Urano S, Saito Y, Taru H, Yamamoto T, Hata S, Suzuki T. Mechanism of intramembrane cleavage of alcadeins by γ-secretase. PLoS One. 2013 Apr 26;8(4):e62431. doi: 10.1371/journal.pone.0062431
Okabe N, Nakamura E, Himi N, Narita K, Tsukamoto I, Maruyama T, Sakakibara N, Nakamura T, Itano T, Miyamoto O. Delayed administration of the nucleic acid analog 2Cl-C.OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke. Brain Res. 2013 Apr 19;1506:115-31.
Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3. Moritoki M, Kadowaki T, Niki T, Nakano D, Soma G, Mori H, Kobara H, Masaki T, Kohno M, Hirashima M. PLoS One May (2013)
当院におけるマージナルドナーからの腎移植成績祖父江　理、乾　政志、原　大雅、藤田　拓朗、野上　浩子、河上　和代、守時　政宏、西岡　聡、西島　陽子、森脇　久美子、林田　有史、上田　修史、筧　善行、河野　雅和日本臨床腎移植学会雑誌 2013.7 Vol1-1 74-77
尿中アンジオテンシノーゲン測定とその臨床的意義について西島陽子、小堀浩幸、水重知子、原大雅、河野雅和循環器内科 2013 June Vol.73 No6 705-711
Short-Term Prognosis of Living-Donor Kidney Transplantation From Hypertensive Donors With High-Normal Albuminuria Sofue Tadashi, Inui Masashi, Hara Taiga, Moriwaki Kumiko, Kushida Yoshio, Kakehi Yoshiyuki, Nishiyama Akira, Kohno Masakazu. Transplantation 2013 Oct.
"Latent IgA deposition from donor kidneys does not affect transplant prognosis,
irrespective of mesangial expansion Sofue T, Inui M, Hara T, Moritoki M, Nishioka S, Nishijima Y, Moriwaki K, Hayashida Y, Ueda N, Kushida Y, Haba R, Nishiyama A, Kakehi Y, Kohno M. Clinical Transplantation 2013: 27 (Suppl. 26): 14-21"
糸球体腎炎患者の尿中に出現する各種細胞の出現状況による病態推定大崎博之、祖父江理、河上和代、則松良明腎臓 2013 Vol.36 No.2
腎移植後再発性IgA 沈着症に関与する因子の検討祖父江理、乾政志、串田吉生、中村英祐、尾崎太郎、河上和代、守時政宏、西岡聡、西島陽子、森脇久美子、原大雅、林田有史、上田修史、筧善行、河野雅和日本臨床腎移植学会雑誌 2013;1(2):186-189
Efficacy and safety of febuxostat in the treatment of hyperuricemia in stable kidney transplant recipients Sofue T, Inui M, Hara T, Nishijima Y, Moriwaki K, Hayashida Y, Ueda N, Nishiyama A, Kakehi Y, Kohno M Drug Design, Development and Therapy 2014 Feb. Vol.8 245-253
Mineral and Bone Disorder is Temporary in Patients Treated With Early Rapid Corticosteroid Reduction After Kidney Transplantation: A Single-Center Experience S Nishioka,T Sofue,M Inui,Y Nishijima,K Moriwaki,T Hara,T Mashiba,Y Kakehi,M Kohno The 13th Congress of the Asian Society of Transplantation Transplantation Proceedings 46 514-520
"Okamoto N1, Noma T, Ishihara Y, Miyauchi Y, Takabatake W, Oomizu S, Yamaoka G, Ishizawa M, Namba T, Murakami K, Iwado Y, Ohmori K, Kohno M.
Prognostic value of circulating regulatory T cells for worsening heart failure in heart failure patients with reduced ejection fraction. Int Heart J. 2014;55(3):271-7. Epub 2014 May 12."
Fan YY, Kobori H, Nakano D, Hitomi H, Mori H, Masaki T, Sun YX, Zhang L, Huang W, Zhu B, Li P, Nishiyama A.Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats.Horm Metab Res. 2013, May;45(5):338-343.
Ohnishi K, Murase M, Nakano D, Pelisch N, Hitomi H, Kobori H, Morimoto S, Mori H, Masaki T, Ohmori K, Kohno M, Ichihara A, Nishiyama A.Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats.　J Pharm Sci. 2013 Jun 20;122(2):103-108.
Liu Y, Hitomi H, Diah S, Deguchi K, Mori H, Masaki T, Nakano D, Kobori H, Nishiyama A　.Roles of Na+/H+ exchanger type 1 and intracellular pH in angiotensin II-induced reactive oxygen species generation and podocyte apoptosis.J Pharm Sci. 2013;122(3):176-183.
Sherajee SJ, Rafiq K, Nakano D, Mori H, Kobara H, Hitomi H, Fujisawa Y, Kobori H, Masaki T, Nishiyama A.Aldosterone aggravates glucose intolerance induced by high fructose. Eur J Pharmacol 2013 Nov 15;720(1-3):63-68.
Rafiq K, Sherajee SJ, Hitomi H, Nakano D, Kobori H, Ohmori K, Mori H, Kobara H, Masaki T, Kohno M, Nishiyama A.Rafiq K, Sherajee SJ, Hitomi H, Nakano D, Kobori H, Ohmori K, Mori H, Kobara H, Masaki T, Kohno M, Nishiyama A.PLoS ONE. 2013 Dec 10;8(12):e82082.
Liu G, Hitomi H, Rahman A, Nakano D, Mori H, Masaki T, Ma H, Iwamoto T, Kobori H, Nishiyama A.　High sodium augments angiotensin II-induced vascular smooth muscle cell proliferation through the ERK 1/2-dependent pathway.Hypertens Res. 2014 Jan;37(1):13-18.
Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation. Fujii M, Kawai K, Egami Y, Araki N. Sci Rep. 2013;3:2385. doi: 1038/srep02385.
Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Maekawa M1, Terasaka S, Mochizuki Y, Kawai K, Ikeda Y, Araki N, Skolnik EY, Taguchi T, Arai H. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E978-87. doi: 10.1073/pnas.1311029111. Epub 2014 Mar 3.
Development of an automated fluorescence microscopy system for photomanipulation of genetically encoded photoactivatable proteins (optogenetics) in live cells. Araki N, Ikeda Y, Kato T, Kawai K, Egami Y, Miyake K, Tsurumaki N, Yamaguchi M. Microscopy (Oxf). 2014 Jun;63(3):255-60. doi: 10.1093/jmicro/dfu003. Epub 2014 Feb 11.
Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro. , Tanaka A., Woltjen K. Miyake K., Hotta A., Ikeya M., Yamamoto T., Nishino T., Shoji E., Sehara-Fujisawa A., Manabe Y., Fujii N., Hanaoka K., Era T., Yamashita S., Isobe K., Kimura E., Sakurai H.,PLoS One. 2013, Apr 23;8(4):e61540.
Nakai K, Yoneda K, Haba R, Kushida Y, Katsuki N, Moriue T, Kosaka H, Kubota Y, Inoue S. Deranged epidermal differentiation in kl/kl mouse and the effects of βKlotho siRNA on the differentiation of HaCaT cells. Exp Dermatol. 2013 Nov;22(11):772-4.
Uyama T, Inoue M, Okamoto Y, Shinohara N, Tai T, Tsuboi K, Inoue T, Tokumura A, Ueda N, Involvement of phospholipase A/acyltransferase-1 in N-acylphosphatidylethanolamine generation. Biochim Biophys Acta - Mol Cell Biol Lipids 1831:1690-1701, 2013
Seiko Shimamot, Mitsumasa Tsuchiya, Fuminori Yamaguchi, Yasuo Kubota, Hiroshi Tokumitsu, Ryoji Kobayashi. 　Ca 2+ /S100 proteins inhibit the interactions of FKBP38 with Bcl-2 and Hsp90　Biochemical Journal　（2013）1-20
"Arif U Hasan, Koji Ohmori, Takeshi Hashimoto, Kazuyo Kamitori, Fuminori Yamaguchi,
Yasuhiro Ishihara, Naoko Ishihara, Takahisa Noma, Masaaki Tokuda, Masakazu Kohno. Valsartan ameliorates constitutive adipokine expression pattern in mature adipocytes,
A role of inverse agonism of angiotensin II type 1 receptor in obesity. 　Hypertension Research　1-37　 "
"Fuminori Yamaguchi, Sho Yamamura, Seiko Shimamoto, Hiroshi Tokumitsu,
Masaaki Tokuda, Ryoji Kobayashi　Suramin is a Novel Activator of PP5 and Biphasically
Modulates S100-Activated PP5 Activity　Appl Biochem Biotechnol　(2013.6)　1-11"
Fuminori Yamaguchi, Yuko Hirata, Hossain Akram, Kazuyo Kamitori, Youyi Dong, Li Sui and Masaaki Tokuda. FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801　BMC Cancer　(2013.10)　1-11
Muneuchi G, Hossain A, Yamaguchi F, Ueno M, Tanaka Y, Suzuki S, Tokuda M. The rare sugar D-allose has a reducing effect against ischemia-reperfusion injury on the rat abdominal skin island flap model. 　J Surg Res Ｖｏｌ.183 (2013.8)976-981
Suna S, Tokuda M, Hirao T, Yamaguchi F, Miyatake N, Suzue T, Asakawa F, Jitsunari F, Izumori K. Protective effect of D-psicose against testicular atrophy induced by di(2-ethylhexyl) phthalate. Int J Environ Stud in Press International Journal of Environmental Studies Vol.70 (2013.6) 560-565
Kazumasa　Osaka, Masaaki　Tokuda, Naohiro　Furukawa. Intra-gastric　triacetin　alters　upper　gastrointestinai　motility　in　conscious　dogs World　Journal　of　Gastroenterolory Vol.20 No.4(2014.1)869-1126
Aldosterone: a mediator of retinal ganglion cell death and the potential role in the pathogenesis in normal-tension glaucoma
Masaki Ueno, Nozomu Nishi, Toshitaka Nakagawa, Yoichi Chiba, Okuko Tsukamoto, Takashi Kusaka, Takanori Miki, Haruhiko Sakamoto, Fuminori Yamaguchi, Masaaki Tokuda. Immunoreactivity of glucose transporter 5 is located in epithelial cells of choroid plexus and ependymal cells. Neuroscience 2014, 260, 149-157.
Liu JQ, Miki T, Matsumoto Y, Ohta K, Suzuki S, Warita K, Yakura T, Tamai M, Takeuchi Y. The role of WGA for decreasing the accumulation of Aβ: A new approach to promote transsynaptic transport of Aβ in the rat. Current Neurobiology 4(1&2) 1-8 2013
"Vega-Carrascal I(1), Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K,Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG.Galectin-9 signaling through TIM-3 is involved in neutrophil-mediatedGram-negative bacterial killing: an effect abrogated within the cystic fibrosislung.J Immunol. 2014 Mar 1;192(5):2418-31. "
"Vega-Carrascal I(1), Bergin DA, McElvaney OJ, McCarthy C, Banville N, Pohl K,
Hirashima M, Kuchroo VK, Reeves EP, McElvaney NG.Galectin-9 signaling through TIM-3 is involved in neutrophil-mediatedGram-negative bacterial killing: an effect abrogated within the cystic fibrosislung.J Immunol. 2014 Mar 1;192(5):2418-31. "
"Kadowaki T, Morishita A, Niki T, Hara J, Sato M, Tani J, Miyoshi H, Yoneyama H,Masaki T, Hattori T, Matsukawa A, Hirashima M(1).Galectin-9 prolongs the survival of septic mice by expanding tim-3-expressingnatural killer T cells and PDCA-1+ CD11c+ macrophages.Crit Care. 2013 Dec 9;17(6):R284. [Epub ahead of print]"
"Katoh S(1), Shimizu H, Obase Y, Oomizu S, Niki T, Ikeda M, Mouri K, Kobashi Y,Hirashima M, Oka M.Preventive effect of galectin-9 on double-stranded RNA-induced airwayhyperresponsiveness in an exacerbation model of mite antigen-induced asthma inmice.Exp Lung Res. 2013 Dec;39(10):453-62."
"Chagan-Yasutan H(1), Ndhlovu LC, Lacuesta TL, Kubo T, Leano PS, Niki T, Oguma S,Morita K, Chew GM, Barbour JD, Telan EF, Hirashima M, Hattori T, Dimaano EM.Galectin-9 plasma levels reflect adverse hematological and immunological featuresin acute dengue virus infection.J Clin Virol. 2013 Dec;58(4):635-40."
"Ma CJ(1), Li GY, Cheng YQ, Wang JM, Ying RS, Shi L, Wu XY, Niki T, Hirashima M,Li CF, Moorman JP, Yao ZQ.Cis association of galectin-9 with Tim-3 differentially regulates IL-12/IL-23expressions in monocytes via TLR signaling.PLoS One. 2013 Aug 14;8(8):e72488."
"Cai L(1), Zhou H, Fang Z, Yuan J, Niki T, Hirashima M, He W, Chen ZK.Galectin-9 in combination with rapamycin induces cardiac allograft tolerance inmice.Transplantation. 2013 Aug 27;96(4):379-86. "
"Gooden MJ(1), Wiersma VR, Samplonius DF, Gerssen J, van Ginkel RJ, Nijman HW,Hirashima M, Niki T, Eggleton P, Helfrich W, Bremer E.Galectin-9 activates and expands human T-helper 1 cells.PLoS One. 2013 May 31;8(5):e65616."
"Moritoki M(1), Kadowaki T, Niki T, Nakano D, Soma G, Mori H, Kobara H, Masaki T,Kohno M, Hirashima M.Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducingplasma cell apoptosis independently of Tim-3.PLoS One. 2013 Apr 9;8(4):e60807. "
"Golden-Mason L(1), McMahan RH, Strong M, Reisdorph R, Mahaffey S, Palmer BE,Cheng L, Kulesza C, Hirashima M, Niki T, Rosen HR.Galectin-9 functionally impairs natural killer cells in humans and mice.J Virol. 2013 May;87(9):4835-45."
松原あい, 宮下武憲, 稲本隆平, 森　　望, ラット内リンパ嚢におけるアドレナリンレセプターの発現, 耳鼻咽喉科ニューロサイエンス, 27（2013）6-9
稲本隆平, 宮下武憲, 森　　望, 　イソプロテレノールの内耳への影響,　　耳鼻咽喉科ニューロサイエンス,　27（2013）10-14
宮下武憲, James Burford, Young-Kwon Hong, 森　　望, Janos Peti-Peterdi, 鼓膜のリンパ管局在、鼓膜再生時の反応, 耳鼻咽喉科ニューロサイエンス, 27（2013）48-49
Yoshikawa K, Shimada M, Kuwahara T, Hirakawa H, Kurita N, Sato H, Utsunomiya T, Iwata T, Miyatani T, Higashijima J, Kashihara H, Takasu C, Matsumoto N, Nakayama-Imaohji H. Effect of Kampo medicine “Dai-kenchu-to” on microbiome in the intestine of the rats with fast stress. J. Med. Invest., 60, 221-227, 2013.
Eguchi H, Miyamoto T, Kuwahara T, Mitamura S, Miamura Y. Infectious conjunctivitis caused by Pseudomonas aeruginosa isolated from a bathroom. BMC Res Notes. 6, 245, 2013.
Ichimura M, Uchida K, Nakayama-Imaohji H, Hirakawa H, Tada T, Morita H, Yasutomo K, Okazaki K, Kuwahara T. Mariner-based transposon mutagenesis for Bacteroides species. J Basic Microbiol, 54, 558-67, 2014

Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies.Nakai K, Yoneda K, Hosokawa Y, Moriue T, Presland RB, Fallon PG, Kabashima K, Kosaka H, Kubota Y.Am J Pathol. 2012 Sep;181(3):969-77.
The mRNA of claudins is expressed in the endolymphatic sac epithelia, Ai Matsubara, Takenori Miyashita, Terushige Mori, Kosuke Akiyama, Ryuhei Inamoto, Nozomu Mori, Auris Nasus Larynx, 39(4),361-364,2012
Presence of adrenergic receptors in rat endolymphatic sac epithelial cells, Ai Matsubara, Takenori Miyashita, Ryuhei Inamoto, Nozomu Mori, J.Membr Biol, 246(2),109-114,2013
Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. Sofue T, Kiyomoto H, Kobori H, Urushihara M, Nishijima Y, Kaifu K, Hara T, Matsumoto S, Ichimura A, Ohsaki H, Hitomi H, Kawachi H, Hayden MR, Whaley-Connell A, Sowers JR, Ito S, Kohno M, Nishiyama A Hypertens Res 25: 604-611, 2012
The optimal timing of antihypertensive medication administration for morning hypertension in patients with cerebral infarction. Hosomi N, Sueda Y, Masugata H, Dobashi H, Murao K, Ueno M, Miki T, Kohno M, Nishiyama A, Matsumoto M Hypertens Res 35: 720-724, 2012
Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation. Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation. Circulation 125: 1402-1413, 2012
Role of (pro)renin receptor in angiotensin II-dependent and -independent EGF receptor transactivation. Shibayama Y, Hitomi H, Nakano D, Kobori H, Mori H, Deguchi K, Masaki T, Ichihara A, Nishiyama A Front Biosci 5: 697-705, 2013
N-type calcium channel inhibition with cilnidipine elicits glomerular podocyte protection independent of sympathetic nerve inhibition. Lei B, Nakano D, Fujisawa Y, Liu Y, Hitomi H, Kobori H, Mori H, Masaki T, Asanuma K, Tomino Y, Nishiyama A. J Pharmacol Sci. 119: 359-367, 2012
Add-On aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan. Lei B, Nakano D, Fan YY, Kitada K, Hitomi H, Kobori H, Mori H, Masaki T, Nishiyama A. J Pharmacol Sci. 119: 131-138, 2012
Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats Kitada K, Nakano D, Liu Y, Fujisawa Y, Hitomi H, Shibayama Y, Shibata H, Nagai Y, Mori H, Masaki T, Kobori H, Nishiyama A 7: e41896, 2012
Aldosterone induces p21-regulated apoptosis via increased synthesis an d secretion of tumour necrosis factor-α in human proximal tubular cells. Cl in Exp Pharmacol Physiol. Kitada K, Nakano D, Hitomi H, Kobori H, Deguchi K, Mori H, Masaki T, Nishiya ma A Clin Exp Pharmacol Physiol 39: 858-863, 2012
Multiphoton imaging of the glomerular permeability of angiotensinogen. Nakano D, Kobori H, Burford JL, Gevorgyan H, Seidel S, Hitomi H, Nishiyama A, Peti-Peterdi J. J Am Soc Nephrol 23: 1847-1866, 2012
Angiotensin II receptor blocker improves salt sensitivity of blood pressure and renal nitric oxide synthesis in type 2 diabetic patients with microalbuminuria. Imanishi M, Okada N, Konishi Y, Morikawa T, Maeda I, Kitabayashi C, Masada M, Shirahashi N, Wilcox CS, Nishiyama A. J Renin Angiotensin-Aldosterone Syst 14: 67-73, 2013
Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats. Fan YY, Kobori H, Nakano D, Hitomi H, Mori H, Masaki T, Sun YX, Zhang L, Huang W, Zhu B, Li P, Nishiyama A. Horm Metab Res 45; 338-343, 2013
The C2A domain in dysferlin is important for association with MG53(TRIM72)・Matsuda C, Miyake K, Kameyama K, Keduka E, Takeshima H, Imamura T, Araki N, Nishino I, Hayashi Y. , PloS Curr.　4:e5035add8caff4,2012
"The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates."Iwata M, Lee Y, Yamashita T, Yagi T, Iwata S, Cameron AD, Maher MJ., Proceedings of the National Academy of Sciences of the UnitedStates of America, 109 (38), 15247-15252, 2012
Sphingosine 1-phosphate attenuates H2O2-induced apoptosis 1 in HaCaT cells cultured in vitro.Moriue T., Igarashi J., Yoneda K., Hashimoto T., Nakai K., Kosaka H., Kubota Y.Clinical and Experimental Dermatology., 38(6): 638 - 645 2013
Dexamethasone induces caveolin-1 in vascular endothelial cells: implications for attenuated responses to VEGF.Igarashi J., Hashimoto T., Shoji K., Yoneda K., Tsukamoto I., Moriue T., Kubota Y., Kosaka H. Am J Physiol Cell Physiol., 304(8): C790 - C800 2013
Uyama T, Ikematsu N, Inoue M, Shinohara N, Jin X-H, Tsuboi K, Tonai T, Tokumura A, Ueda N, Generation of N-acylphosphatidylethanolamine by members of the phospholipase A/acyltransferase (PLA/AT) family. J Biol Chem 287:31905-31919, 2012
Yamano Y, Tsuboi K, Hozaki Y, Takahashi K, Jin X-H, Ueda N, Wada A, Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase. Bioorg Med Chem 20:3658-3665, 2012
Tai T, Tsuboi K, Uyama T, Masuda K, Cravatt BF, Houchi H, Ueda N, Endogenous molecules stimulating N-acylethanolamine-hydrolyzing acid amidase (NAAA). ACS Chem Neurosci 3:379-385, 2012
Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site. Nonaka Y, Ogawa T, Oomizu S, Nakakita S, Nishi N, Kamitori S, Hirashima M, Nakamura T. J Biochem.153(5) 463-471 2013
Bin Wu, Masaki Ueno, Takashi Kusaka, Takanori Miki, Yukiko Nagai, Toshitaka Nakagawa, Kenji Kanenishi, Naohisa Hosomi, Haruhiko Sakamoto. CD36 expression in the brains of SAMP8. Archives of Gerontology and Geriatrics, 2013, 56, 75-79.
Reduced diversity and imbalance of fecal microbiota in patients with ulcerative colitis. Nemoto H, Kataoka K, Ishikawa H, Ikata K, Arimochi H, Iwasaki T, Ohnishi Y, Kuwahara T, Yasutomo K. Dig Dis Sci, 57, 2955-2964, 2012.
PhoB regulates the survival of Bacteroides fragilis in peritoneal abscesses. Wakimoto S, Nakayama-Imaohji H, Ichimura M, Morita H, Hirakawa H, Hayashi T, Yasutomo K, Kuwahara T. PLoS One, 8, e53829, 2013.
Mariner-based transposon mutagenesis for Bacteroides species. Ichimura M, Uchida K, Nakayama-Imaohji H, Hirakawa H, Tada T, Morita H, Yasutomo K, Okazaki K, Kuwahara T. J Basic Microbiol, 2013, in press.
Early Treatment With Olmesartan Prevents Juxtamedullary Glomerular Podocyte Injury and the Onset of Microalbuminuria in Type 2 diabetic Rats/Tadasi Sofue,Hideyasu Kiyomoto,Hiroyuki Kobori,Maki Urushihara,Yoko Nishijima,Kumiko Kaifu,Taiga Hara,Sachiko Matsumoto,Atsuhiko Ichimura,Hiroyuki Ohsaki,Hirofumi Hitomi,Hiroshi Kawachi,Melvin R. Hayden,Adam Whaley-Connell,James R. Sowers,Sadayoshi Ito,Masakazu Kohno, Akira Nishiyama/Am J Hypertens vol.25 No.5 P604-611/2012
Oomizu S, Arikawa T, Niki T, Kadowaki T, Ueno M, Nishi N, Yamauchi A, Hattori T, Masaki T, Hirashima M. Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion. PLoS One. 2012;7(11):e48574.
Yoshida H, Yamashita S, Teraoka M, Itoh A, Nakakita S, Nishi N, Kamitori S. X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains. FEBS J. 2012 Oct;279(20):3937-51.
Arikawa T, Simamura E, Shimada H, Nishi N, Tatsuno T, Ishigaki Y, Tomosugi N, Yamashiro C, Hata T, Takegami T, Mogami H, Yamaguchi K, Nakamura T, Otani H, Hatta T, Shoji H. Expression pattern of Galectin 4 in rat placentation. Placenta. 2012 Oct;33(10):885-7.
Wiersma VR, de Bruyn M, van Ginkel RJ, Sigar E, Hirashima M, Niki T, Nishi N, Samplonius DF, Helfrich W, Bremer E. The glycan-binding protein galectin-9 has direct apoptotic activity toward melanoma cells. J Invest Dermatol. 2012 Sep;132(9):2302-5.
Oomizu S, Arikawa T, Niki T, Kadowaki T, Ueno M, Nishi N, Yamauchi A, Hirashima M. Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner. Clin Immunol. 2012 Apr;143(1):51-8.
Wu B, Ueno M, Kusaka T, Miki T, Nagai Y, Nakagawa T, Kanenishi K, Hosomi N, Sakamoto H. CD36 expression in the brains of SAMP8. Arch Gerontol Geriatr. 2013 Jan-Feb;56(1):75-9.
Yoneda K, Nakagawa T, Lawrence OT, Huard J, Demitsu T, Kubota Y, Presland RB. Interaction of the profilaggrin N-terminal domain with loricrin in human cultured keratinocytes and epidermis. J Invest Dermatol. 2012 Apr;132(4):1206-14.
Lei B, Nakano D, Fujisawa Y, Liu Y, Hitomi H, Kobori H, Mori H, Masaki T, Asanuma K, Tomino Y, Nishiyama A. N-type calcium channel inhibition with cilnidipine elicits glomerular podocyte protection independent of sympathetic nerve inhibition. J Pharmacol Sci. 2012;119(4):359-67.
Kitada K, Nakano D, Liu Y, Fujisawa Y, Hitomi H, Shibayama Y, Shibata H, Nagai Y, Mori H, Masaki T, Kobori H, Nishiyama A. Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats. PLoS One. 2012;7(7):e41896.

Masakazu Harada, Emi Kondo, Hiromi Hayashi, Chigusa Suezawa, Setsuo Suguri and Meiji Arai.,D-Allose and D-psicose reinforce the action of metronidazole on trichomonad.Parasitol Res (2012) 110:1565－1567
Yang Y, Yamashita T, Nakamaru-Ogiso E, Hashimoto T, Murai M, Igarashi J, Miyoshi H, Mori N, Matsuno-Yagi A, Yagi T, Kosaka H., Reaction mechanism of single subunit NADH-ubiquinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae: evidence for a ternary complex mechanism., Journal of Biological Chemistry. 2011 286: 9287-9297.
Jun-Qian Liu, Takanori Miki, Katsuhiko Warita, Ken-ichi Ohta, Shingo Suzuki, Tomiko, Yakura, Motoki Tamai, Yoshiki Matsumoto, Yoshiki Takeuchi,Reassessment of secretion manner from neurosecretory terminals in the rat posterior pituitary.,Current Neurobiology, 2011, 2(2), 89-91
Yoshiki Takeuchi, Yoshiki Matsumoto, Takanori Miki, Katsuhiko Warita, Zhi-Yu, Wang, Kuldip S. Bedi, Tomoko Yakura, Jun-Qian Liu,Alteration of the Expression Levels of Rab3A Affects the Extent of Transcytisis of HRP-Labeled Marker Proteins in Rat CNS Neurons,Neuroscience & Medicine, 2011,2,282-287
Tsuboi K, Okamoto Y, Ikematsu N, Inoue M, Shimizu Y, Uyama T, Wang J, Deutsch DG, Burns MP, Ulloa NM, Tokumura A, Ueda N, Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. Biochim Biophys Acta - Mol Cell Biol Lipids 1811:565-577, 2011
Shinohara N, Uyama T, Jin X-H, Tsuboi K, Tonai T, Houchi H, Ueda N, Enzymological analysis of the tumor suppressor A-C1 reveals a novel group of phospholipid-metabolizing enzymes. J Lipid Res 52:1927-1935, 2011
Uyama T, Ichi I, Kono N, Inoue A, Tsuboi K, Jin X-H, Araki N, Aoki J, Arai H, Ueda N, Regulation of peroxisomal lipid metabolism by catalytic activity of tumor suppressor H-rev107. J Biol Chem 287:2706-2718, 2012
Ｆｃγレセプター介在性貪食を司る機械分子と制御シグナルの可視化,医生電顕技術誌, 25(2), (2011)
Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during FcγR-mediated phagocytosis,Jounal of Cell Science, 124 (2011), 3557-3567
Kanaji N, Bandoh S, Ishii T, Kushida Y, Haba R, Kohno K, Dobashi H, Ohnishi H, Matsunaga T. Detection of epidermal growth factor receptor mutations in a few cancer cells from transbronchial cytologic specimens by reverse transcriptase-polymerase chain reaction. Mol Diagn Ther. 2011 Dec 1;15(6):353-9.
Lipid peroxidation-induced VEGF expression in the skin of KKAy obese mice. Nakai, K., Yoneda, K., Ishihara, Y., Ohmori, K., Moriue, T., Igarashi, J., Kohno, M., Kosaka, H., and Kubota, Y. Exp Dermatol 20, 388-393 (2011)
H. Yoshida, M. Teraoka, A. Yoshihara, K. Izumori & S. Kamitori, Overexpression, crystallization and preliminary X-ray diffraction analysis of L-ribose isomerase from Acinetobacter sp. strain DL-28, Acta crystallogr F 67(10), 1281-1284, (2011)
J. Iwaki, H. Tateno, N. Nishi, T. Minamisawa, S. Nakamura-Tsuruta, Y. Itakura, J. Kominami, T. Urashima, T. Nakamura, J. Hirabayashi.The Galβ-(syn)-gauche configuration is required for galectin-recognition disaccharides. Biochim Biophys Acta. 1810(7): (2011) 643-51.
Kuwahara T, Ogura Y, Oshima K, Kurokawa K, Ooka T, Itoh T, Nakayama-Imaohji H, Ichimura M, Itoh K, Ishifune C, Maekawa Y, Yasutomo K, Hattori M, Hayashi T. The lifistyle of the segmented filamentous bactrium: a non-culturable gut-associated immunostimulating microbe inferred by whole-genome sequencing. DNA Research, Vol.18, No.4(2011)291-303.
Nariya H, Miyata S, Kuwahara T and Okabe A: Development and characterization of a xylose-inducible gene expression system for Clostridium perfringens. Appl Environ Microbiol. 77: 8439-8441, 2011
Aldsterone induces insulin-like growth factor-1 receptor and hybrid receptor.,Sherajee SJ, Fujita Y, Rafiq K, Nakano D, Mori H, Masaki T, Hara T, Kohno M, Nishiyama A, Hitomi H.,Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):257-63.
Roles of central renin-angiotensin system and afferent renal nerve in the control of systemic hemodynamics in rats.Fujisawa Y, Nagai Y, Lei B, Nakano D, Fukui T, Hitomi H, Mori H, Masaki T , Nishiyama A. Hypertens. Res. 2011 Nov;34(11):1228-32.
Short-term calorie restriction in early life attenuates the development of proteinuria but not glucose intolerance in type 2 diabetic OLETF rats.Nakano D, Diah S, Kitada K, Hitomi H, Mori H, Masaki T, Kobori H, Nishiyama A　ISRN Endocrinology. 2011;2011:768637.
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.Nakano D, Lei B, Kitada K, Hitomi H, Kobori H, Mori H, Deguchi K, Masaki T, Minamino T, Nishiyama A.Am J Hypertens. 2012 Mar;25(3):354-8.
Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation.　Rafiq K, Noma T, Fujisawa Y, Ishihara Y, Arai Y, Navi AHMN, Suzuki F,Nakano D, Hitomi H, Kitada K, Urushihara M, Kobori H, Kohno M, Nishiyama A.　Circulation. 2012 Mar 20;125(11):1402-13.
Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via EGF receptor-mediated ERK and Akt activation pathway.Liu G, Hitomi H, Nosomi N, Shibayama Y, Nakano D, Kiyomoto H, Ma H, Yamaji Y, Kohno M, Ichihara A, Itoh H, Nishiyama A.　J. Hypertens. 2011 Apr;29(4):696-705
Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor.Liu G, Hitomi H, Hosomi N, Lei B, Nakano D, Deguchi K, Mori H, Masaki T, Ma H, Griendling KK, Nishiyama A.　Exp Cell Res. 2011 Oct 15;317(17):2420-8.
Angiotensin II induces human astrocyte senecence through reactive oxygen species production.,Liu G, Hosomi N, Hitomi H, Pelish N, Fu H, Masugata H, Murao K, Ueno M, Matsumoto M, Nishiyama A.Hypertens.Res. 2011 Apr;34(4):479-83.
D.Gao, N.Kawai, T.Tamiya, The anti-inflammatory effects of D-allose contribute to attenuation of cerebral ischemia-reperfusion in ijury, Med Hypotheses, 2011 Jun;76(6):911-3
H.Zhen, N.Kawai, K.Miyake, M.Okada, S.Okubo, X.Zhang, Z.Fei, T.Tamiya, Relation of LAT1/4F2hc expression with pathological grade, proliferation and angiogenesis in human gliomas. BMC Clin Pathol, 2012 Feb 28;12:4

H.Hoshikawa, T.Mori, N.Mori, In vitro and in vivo effects of D-allose:Up-regulation of thioredoxin-interacting protein in head and neck cancer cells. Annals of Otology,Rhinology & Laryngology, 119(8),567-571,2010
Yang Y, Yamashita T, Nakamaru-Ogiso E, Hashimoto T, Murai M, Igarashi J, Miyoshi H, Mori N, Matsuno-Yagi A, Yagi T, Kosaka H. Reaction mechanism of single subunit NADH-ubiquinone oxidoreductase (Ndi1) from Saccharomyces cerevisiae: evidence for a ternary complex mechanism. 286(11):9287-97, 2011
Yoneda K, Demitsu T, Manabe M, Igarashi J, Kosaka H, Inagaki N, Takahashi H, Kon A, Kakuai M and Kubota Y. Expression of wild-type, but not mutant, loricrin causes programmed cell death in HaCaT keratinocytes. The Journal of Dermatology. 37(11): 956-64, 2010.
Tsukamoto I, Sakakibara N, Maruyama T, Igarashi J, Kosaka H, Kubota Y, Tokuda M, Ashino H, Hattori K, Tanaka S, Kawata M and Konishi R. A novel nucleic acid analogue shows strong angiogenic activity. Biochem Biophys Res Commun. 399(4):699-704, 2010.
Yoneda K, Demitsu T, Nakai K, Moriue T, Ogawa W, Igarashi J, Kosaka H, and Kubota Y. Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma. J Biol Chem. 285(21):16184-94, 2010.
Murai M, Yamashita T, Senoh M, Mashimo Y, Kataoka M, Kosaka H, Matsuno-Yagi A, Yagi T, Miyoshi H. Characterization of the Ubiquinone Binding Site in the Alternative NADH-Quinone Oxidoreductase of Saccharomyces cerevisiae by Photoaffinity Labeling. Biochemistry, 49(13):2973-2980, 2010
樋本尚志、米山弘人、出口章広、黒河内和貴、正木　勉, 自己免疫現象を伴うC型慢性肝炎における血清B lymphocyte activating factor(BAFF)値測定の意義について　消化器と免疫　47: 116-119, 2010
Himoto T, Yoneyama H, Deguchi A, Kurokohchi K, Inukai M, Masugata H, Goda F, Senda S, Haba R, Watanabe S, Nishioka M, Masaki T.,Relationship between the production of autoantibodies to oxidized low-density lipoprotein and hepatic steatosis in patients with chronic hepatitis C.,Exp Ther Med　1: 663-668, 2010
Himoto T, Yoneyama H, Deguchi A, Kurokohchi K, Inukai M, Masugata H, Goda F, Senda S, Watanabe S, Kubota S, Kuriyama S, Masaki T.,Insulin resistance derived from zinc deficiency in non-diabetic patients with chronic hepatitis C.,Exp Ther Med　1: 707-711, 2010
Himoto T, Murota M, Yoneyama H, Deguchi A, Kurokohchi K, Senda S, Haba R, Watanabe S, Nishioka M, Masaki T.
Clinical characteristics of patients with autoimmune hepatitis seropositive for anticentromere antibody.,Hepatol Res　40: 786-792, 2010
Morishita A, Gong J, Nomura T, Yoshida H, Izuishi K, Suzuki Y, Kushida Y, Haba R, D'armiento J, Masaki T.
The use of protein array to identify targetable receptor tyrosine kinases for treatment of human colon cancer.,Int J Oncol　37: 829-835, 2010
Liu S, Gong J, Morishita A, Nomura T, Miyoshi H, Tani J, Kato K, Yoneyama H, Deguchi A, Mori H, Mimura S, Nomura K, Himoto T, Deguchi K, Okano K, Izuishi K, Suzuki Y, Kushida Y, Haba R, Iwama H, Masaki T.
Use of protein array technology to investigate receptor tyrosine kinases activated in hepatocellular carcinoma.,Exp Ther Med　2: 399-403, 2011
Liu JQ , Miki T , Warita K , Ohta K , Yakura T , Matsumoto Y, Takeuchi Y . Revaluation of neuronal contacts with pituicytes in the rat posterior pituitary . Current Neurobiology, 2011, 2(1) :1-4
T.Ishikawa,Y.Yasuoka,S.Tokonami,H.Takahashi,H.Suda,Characterization of airborne radon released by domestic showering and the use of a washing machine. Journal of Radioanalytical and Nuclear Chemistry,Vol.279,No3(2010)719-724
Ueda, N., Tsuboi, K., Uyama, T., Enzymological studies on the biosynthesis of N-acylethanolamines. Biochim Biophys Acta - Mol Cell Biol Lipids 1801:1274-1285, 2010
Ueda. N., Tsuboi, K., Uyama, T., N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA). Prog Lipid Res 49:299-315, 2010
Identification and characterization of PRG-1 as a neuronal calmodulin-binding protein.,Tokumitsu H, Hatano N, Tsuchiya M, Yurimoto S, Fujimoto T, Ohara N, Kobayashi R, Sakagami H.,Biochem J. 2010 Oct 1;431(1):81-91.
Regulation of nuclear localization signal-importin α interaction by Ca2+/S100A6.,Takata M, Shimamoto S, Yamaguchi F, Tokuda M, Tokumitsu H, Kobayashi R.,FEBS Lett. 2010 Nov 19;584(22):4517-23. Epub 2010 Oct 21.
Exendin-4 regulates GLUT2 expression via the CaMKK/CaMKIV pathway in a pancreatic β-cell line.,Chen K, Yu X, Murao K, Imachi H, Li J, Muraoka T, Masugata H, Zhang GX, Kobayashi R, Ishida T, Tokumitsu H.,Metabolism. 2011 Apr;60(4):579-85. Epub 2010 Jul 3.
Exendin-4 regulates pancreatic ABCA1 transcription via CaMKK/CaMKIV pathway.,Li J, Murao K, Imachi H, Masugata H, Iwama H, Tada S, Zhang GX, Kobayashi R, Ishida T, Tokumitsu H.,J Cell Mol Med. 2010 May;14(5):1083-7. Epub 2009 Oct 29.
Transcriptional factor prolactin regulatory element-binding protein-mediated gene transcription of ABCA1 via 3',5'-cyclic adenosine-5'-monophosphate.,Nishiuchi Y, Murao K, Imachi H, Nishiuchi T, Iwama H, Ishida T.,Atherosclerosis. 2010 Oct;212(2):418-25
Calcium/calmodulin-dependent protein kinase IV involvement in the pathophysiology of glucotoxicity in rat pancreatic β-cells.,Sugiyama Y, Murao K, Imachi H, Sueyoshi N, Ishida T, Kameshita I.,Metabolism. 2011 Jan;60(1):145-53.
Hyperglycemia suppresses ABCA1 expression in vascular smooth muscle cells.,Yu X, Murao K, Imachi H, Li J, Nishiuchi T, Hosomi N, Masugata H, Zhang GX, Iwama H, Ishida T.,Horm Metab Res. 2010 Apr;42(4):241-6.
Exendin-4 regulates pancreatic ABCA1 transcription via CaMKK/CaMKIV pathway.,Li J, Murao K, Imachi H, Masugata H, Iwama H, Tada S, Zhang GX, Kobayashi R, Ishida T, Tokumitsu H.,J Cell Mol Med. 2010 May;14(5):1083-7.
Menin, a product of the MENI gene, binds to estrogen receptor to enhance its activity in breast cancer cells: possibility of a novel predictive factor for tamoxifen resistance.,Imachi H, Murao K, Dobashi H, Bhuyan MM, Cao X, Kontani K, Niki S, Murazawa C, Nakajima H, Kohno N, Yamashita H, Iwase H, Hayashi S, Ishida T, Yamauchi A.,Breast Cancer Res Treat. 2010 Jul;122(2):395-407.
H. Yoshida, K. Takeda, K. Izumori & S. Kamitori, Elucidation of the role of Ser329 and the C-terminal region in the catalytic activity of Pseudomonas stutzeri L-rhamnose isomerase, Protein Eng. Des. Sel., 23(12), 919-927, (2010)
K. Takeda, H. Yoshida, K. Izumori & S. Kamitori, X-ray Structures of Bacillus pallidus D-Arabinose Isomerase and Its Complex with L-Fucitol, Biochim Biophys Acta － Proteins and Proteomics. , 1804(6), 1359-1368, (2010)
X-ray structures of human galectin-9 C-terminal domain in complexes with a biantennary oligosaccharide and sialyllactose.,Yoshida H, Teraoka M, Nishi N, Nakakita S, Nakamura T, Hirashima M, Kamitori S.,J Biol Chem. 2010 Nov 19;285(47):36969-76. Epub 2010 Sep 22.,PMID: 20861009 [PubMed - indexed for MEDLINE] Related citations
Tissue-specific expression of fucosylated glycosphingolipid species in rat prostate.,Miyanaka H, Nakamura T, Nishi N.,Biosci Biotechnol Biochem. 2010;74(6):1261-6. Epub 2010 Jun 7.,PMID: 20530880 [PubMed - indexed for MEDLINE] Free Article Related citations
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Nariya H, Miyata S, Suzuki M, Tamai E, and Okabe A. (2011),Development and application of a method for counterselectable in-frame deletion in Clostridium perfringens.”,Appl Environ Microbiol. 2011. 77(4):1375-1382. 査読有
Tanaka H, Nariya H, Suzuki M, Houchi H, Tamai E, Miyata S, Okabe A. (2011),High-level production and purification of clostripain expressed in a virulence-attenuated strain of Clostridium perfringens.”,Protein Expr Purif. 2011. 76(1):83-89. 査読有
Arikawa T, Saita N, Oomizu S, Ueno M, Matsukawa A, Katoh S, Kojima K, Nagahara K, Miyake M, Yamauchi A, Kohrogi H, and Hirashima M. Galectin-9 expands immunosuppressive macrophages to ameliorate T cell-mediated lung inflammation. Eur J Immunol, 40(2): 548-558, 2010
Tsutomu Kobayashi, Junya Kuroda, Eishi Ashihara, Souichi Oomizu, Yasuhito Terui, Akiko Taniyama, Satoko Adachi, Tomohisa Takagi, Mio Yamamoto, N Sasaki, S Horiike, Kiyohiko Hatake, Akira Yamauchi, Mitsuomi Hirashima, Masafumi Taniwaki. Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways. Leukemia 24 (4): 843-850, 2010.
Rena Tanikawa, Takahisa Tanikawa, Mitsuomi Hirashima, Akira Yamauchi, Yoshiya Tanaka. Galectin-9 induces osteoblast differentiaion through the CD44/Smad signaling pathway. BBRC 394(2): 317-322, 2010.
Shigeki Katoh, Atsuya Nobumoto, Nobuhiro Matsumoto, Kiyoshi Matsumoto, Naomi Ehara, Toshiro Niki, Hiroyuki Inada, Nozomu Nishi, Akira Yamauchi, Kiyoyasu Fukushima, Mitsuomi Hirashima. Involvement of galectin-9 in lung eosinophilia in patients with eosinophilic pneumonia. Int. Arch. Allergy Immunol. 153(3): 294-302, 2010.
Junya Kuroda, Mio Yamamoto, Hisao Nagoshi, Tsutomu Kobayashi, Nana Sasaki, Y Shimura, S Horiike, Shinya Kimura, Akira Yamauchi, Mitsuomi Hirashima, Masahfumi Taniwaki. Targeting activating transcription factor 3 by galectin-9 induces apoptosis and overcomes various types of treatment resistance in chronic myelogenous leukemia. Molecular Cancer Research, 8 (7): 994-1001. 2010.
Kadowaki T, Inagawa H, Kohchi C, Hirashima M, Soma G. Preparation of lipopolysaccharide derived from Pantoea agglomerans labeled with fluorescence as a tracer for kinetics analysis. Anticancer Res 30(8): 3151-3157, 2010.
Valerie Dardalhon, Ana C Anderson, Jozsef Karman, Lionel Apetoh, Rucha Chandwaskar, David H. Lee, Melanie Cornejo, Nozomu Nishi, Akira Yamauchi, Francisco J. Quintana, Raymond A. Sobel, Mitsuomi Hirashima, Vijay K. Kuchroo. Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. J. Immunol. 185: 1383-1392, 2010.
Rashmi Mishra, Michal Grzybek, Toshiro Niki, Mitsuomi Hirashima, Kai Simons. Galectin-9 trafficking regulates apical-basal polarity in Madin-Darby canine kidney epithelial cells. PNAS 107 (41): 17633-17638, 2010.
John A. Mengshol, Lucy Golden-Mason, Tomohiro Arikawa, Maxwell Smith, Toshiro Niki, Ryan McWilliams, Jessica Randall, Rachel McMahan, Manu Rangachari, Evgenia Dobrinskikh, Pierre Busson, Stephen J. Polyak, Mitsuomi Hirashima, Hugo R. Rosen. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in chronic hepatitis C infection. Plos One 5(3): e9504, 2010.
Sharvan Sehrawat, Pradeep B J Reddy, Naveen Rajasagi, Amol Suryawanshi, Mitsuomi Hirashima, Barry T Rouse. Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8+ T cell response. PLOS Pathogens 6 (5): e1000882, 2010.
Tim Horlacher, Matthias A. Oberli, Daniel B. Werz, Lenz H. Krock, Simone Bufali, Bridget Stocker, Rashmi Mishra, Jens Sobek, Kai Simons, Mitsuomi Hirashima, Toshiro Niki, Peter H. Seeberger. Determination of carbohydrate-binding preferences of human galectins with carbohydrate microarrays. ChemBioChem 11 (11): 1563-1573, 2010.
Haorile Chagan-Yasutan, Beata Shiratori, Umme Ruman Siddiqi, Hiroki Saitoh, Yugo Ashino, Tomohiro Arikawa, Mitsuomi Hirashima, Toshio Hattori. The increase of plasma galectin-9 in a patient with insulin allergy: a case report. Clin Mol Allergy 8: 12 (1-4), 2010.
Hiromi Yoshida, Misa Teraoka, Nozomu Nishi, Shin-ichi Nakakita, Takanori Nakamura, Mitsuomi Hirashima. Shigehiro Kamitori. Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis. J Biol Chem 285 (47): 36969-36976 2010.
Sakai Kazuki, Kawata Eri, Ashihara Eishi, Nakagawa Yoko, Yamauchi Akira, Yao Hisayuki, Nagao Rina, Tanaka Ruriko, Yokota Asumi, Takeuchi, Miki, Hirai Hideyo, Kimura Shinya, Hirashima Mitsuomi, Yoshimura Norio, Maekawa Taira. Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis. Eur J Immunol 41(1): 67-75, 2011, 2011.
Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG. Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways. J. Immunol. 186(5): 2897-2909 2011.
Iqbal AJ, Sampaio AL, Maione F, Greco KV, Niki T, Hirashima M, Perretti M, Cooper D. Endogenous galectin-1 and acute inflammation: emerging notion of a galectin-9 pro-resolving effect. Am. J. Pathol. 178(3): 1201-1209 2011.
Inoue M, Moriwaki Y, Arikawa T, Chen YH, Oh YJ, Oliver T, Shinohara ML. Cutting edge: critical role of intracellular osteopontin in antifungal innate immune responses. J Immunol 186(1):19-23, 2011.
Liu G, Miyata K, Hitomi H, Yao L, Sun GP, Suzaki Y, Hosomi N, Kiyomoto H, Nakano D, Tamaki T, Yoshizumi Y, Nishiyama A,Involvement of mineralocorticoid receptor in high glucose-induced BMK1 activation and mesangial cell proliferation.J Hypertension, 28: 536-542, 2010
Nishiyama A, Kobori H, Konishi Y, Morikawa T, Maeda I, Okumura M, Kishida M, Hamada M, Nagai Y, Nakagawa T, Ohashi N, Nakano D, Hitomi H, Imanishi M, Mineralocorticoid receptor blockade enhances the anti-proteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic, J. Pharmacol. Exp. Ther, 332: 1072-1080, 2010
Pelisch N, Hosomi N, Ueno M, Masugata H, Murao K, Hitomi H, Nakano D, Kobori H, Nishiyama A, Kohno M, Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system. Hypertens Res, 2010
Fan Y-Y, Kohno M, Nakano D, Ohsaki H, Kobori H, Diah S, Ohashi N, Hitomi H, Asanuma K, Noma T, Tomino Y, Fujita T, Nishiyama A, Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats; possible involvement of N-type calcium channel in podocyte. J. Hypertens 28: 1034-1043, 2010
Zhang W, Kawanishi M, Miyake K, Kagawa M, Kawai N, Murao K, Nishiyama A, FeiZ, Zhang X, Tamiya T, Association between YKL-40 and adult primary astrocytoma.Cancer, 116: 2688-2697, 2010
Liu G, Hitomi H, Hosomi N, Lei B, Pelish N, Nakano D, Kiyomoto K, Ma H, Nishiyama A, Mechanical stretch potentiates angiotensin II-induced proliferation in spontaneously hypertensive rat vascular smooth muscle cells. Hypertens. Res, 33: 1250-1257, 2010
Ihara G, Kiyomoto H, Kobori H, Nagai Y, Ohashi N, Hitomi H, Nakano D, Pelisch N, Hara T, Mori T, Ito S, Kohno M, Nishiyama A, Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade.J. Hypertens, J. Hypertens
Nishiyama A, Konishi Y, Ohashi N, Morikawa T, Urushihara M, Maeda I, Hamada M, Kishida M, Hitomi H, Shirahashi N, Kobori H, Imanishi M, Urinary angiotensinogen reflects the activity of intrarenal renin-angiotensin system in patients with IgA nephropathy.Nephrol Dial Transplant, 26: 170-177, 2011
Rafiq K, Nakano D, Hitomi H, Ihara G, Nagai Y, Fujisawa Y, Ohashi N, Kobori H, Kiyomoto H, Kohno M, Nishiyama A, Effects of mineralocorticoid receptor blockade on glucocorticoid-induced renal injury in adrenalectomized,J Hypertens.29: 290-298, 2011
Pelisch N, Hosomi N, Ueno M, Nakano D, Hitomi H, Mogi M, Shimada K, Kobori H, Horiuchi M, Sakamoto H, Matsumoto M, Kohno M, Nishiyama A, Blockade of AT1 receptors protects the blood brain barrier and cognition in Dahl salt-sensitive hypertensive rats. Am J Hypertens. 24: 362-368, 2011
Fan YY, Kohno M, Hitomi H, Kitada K, Fujisawa Y, Yatabe J, Yatabe M, Felder RA, Ohsaki H, Rafiq K, Sherajee SJ, Noma T, Nishiyama A, Nakano D. Aldosterone/mineralocorticoid receptor stimulation induces cellular senescence in the kidney. Endocrinology.152: 680-688, 2011

Uyama T, Morishita J, Jin X-H, Okamoto Y, Tsuboi K, Ueda N, The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase-type. J Lipid Res 145: 43-50, 2009
Uyama T, Jin X-H, Tsuboi K, Tonai T, Ueda N, Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes. Biochim Biophys Acta - Mol Cell Biol Lipids 1791: 1114-24, 2009
Wang J, Ueda N, Biology of endocannabinoid synthesis system. Prostaglandins Other Lipid Mediat 89: 112-9, 2009
Okamoto Y, Tsuboi K, Ueda N, Enzymatic formation of anandamide. Vitam Horm 81: 1-24, 2009
Yoshida, H., Yamaji, M, Ishii, T., Izumori, K. & Kamitori, S. (2009). Catalytic reaction mechanism of Pseudomonas stutzeri L-rhamnose isomerase deduced from X-ray structures. FEBS J. 277(4), 1045-1057
Yoshiki Takeuchi, Yoshiki Matsumoto, Takanori Miki, Toshifumi Yokoyama, Katsuhiko Warita, Zhi-Yu Wang, Takashi Ueno, Tomiko Yakura, Mamoru Fujita, Anterograde synaptic transport of neuronal tracer enzyme (WGA-HRP): Further studies with Rab3A-siRNA in rats. Biomedical Research 2009, 20(3):149-154
Yoshiki Takeuchi, Yoshiki Matsumoto, Takanori Miki, Katsuhiko Warita, Zhi-Yu Wang , Tomiko Yakura, Jun-Qian Liu, A protein conjugation of WGA essential for transsynaptic tracer in neuronal system: application for Amyloid-β in vivo. DRD2009
Kazutoshi Fusumada, Toshifumi Yokoyama, Takanori Miki, Yoshiki Matsumoto, Katsuhiko Warita, Zhi-Yu Wang, Tomiko Yakura, Jun-Qian Liu, Yoshiki Takeuchi, GABA expression in c-Fos immunoreactive neurons of the rat periaqueductal gray induced by electro-acu-pun-c-ture at the point of Zusanli, Current Neurobiol 2010, 1(1):10-13
Takashi Ueno, Takanori Miki, Zhi-Yu Wang, Toshifumi Yokoyama, Kyoung-Youl Lee, Takashi Kusaka, Katsuhiko Warita Kazunori Sumitani, Yoshiki Matsumoto, Tomiko Yakura, Jun-Qian Liu, Kuldip S. Bedi, Yoshiki Takeuchi, Effects of short-term ethanol ingestion on the expression of neurotrophins and their receptors: No changes in the expression of the glial-derived neurotrophic factor in the mouse hippocampus. Current Neurobiology, 2010 1(1):40-45
Zhi-Yu Wang, Takanori Miki, Kyoung-Youl Lee, Toshifumi Yokoyama, Takashi Kusaka, Kazunori Sumitani, Kazuhiko Warita, Yoshiki Matsumoto, Tomiko Yakura, Naonaga Hosomi, Kiyoshi Ameno, Kuldip S. Bedi、Yoshiki Takeuchi, Short-term exposure to ethanol causes a differential response between nerve growth factor and brain-derived neurotrophic factor ligand/receptor systems in the mouse cerebellum. Neuroscience 2010, 165(2):485-491
Pelisch N, Hosomi N, Ueno M, Masugata H, Murao K, Hitomi H, Nakano D, Kobori H, Nishiyama A, Kohno M., Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system. Hypertens Res., Vol.33, No.2(2010)161-4.
森　　望、メニエール病の最近の話題、日耳鼻群馬県地方部会報, 27, 1-3, 2009
H.Hoshikawa, R.Goto, T.Mori, T.Mitani, N.Mori, Expression of prostaglandin E2 receptors in oral squamous cell carcinomas and growth inhibitory effects of an EP3 selective antagonist, ONO-AE3-240, Int J Oncology, 34, 847-852, 2009
T.Mori, T.Miyashita, K.Akiyama, R.Inamoto, N.Mori, The expression of P2Y1,2,4,and 6 receptors in rat endolymphatic sac epithelia, Neuroreport, 20(4), 419-423, 2009
稲本隆平、宮下武憲、森　　望、内リンパ嚢の内リンパ圧調節における役割に関する研究、頭頸部自律神経　23, 36-39, 2009
T.Mitani, H.Hoshikawa, T.Mori, T.Hosokawa, I.Tsukamoto, F.Yamaguchi, K.Kamitori, M.Tokuda, N.Mori Growth inhibition of head and neck carcinomas by D-allose, Head and Neck, 31(8), 1049-1055, 2009
K.Akiyama, M.Karaki, R.Kobayashi, H.Dobashi, T.Ishida, N.Mori, IL-16 variability and modulation by antiallergic drugs in a murine experimental allergic rhinitis model, Int.Arch.Allergy Immunology, 149, 315-322, 2009
K.Akiyama, T.Miyashita, A.Matsubara, R.Inamoto, T.Mori, A.Nishiyama, N.Mori, Expression and localization of 11β-hydroxysteroid dehydrogenase(11βHSD) in the rat endolymphatic sac, Acta Oto-Laryngologica, 130(2), 228-232, 2010
R.Inamoto, T.Miyashita, K.Akiyama, T.Mori, N.Mori, Endolymphatic sac is involved in the regulation of hydrostatic pressure of cochlear endolymph, Am J Physiol Regul Integr Comp, 297, R1610-R1614, 2009
Nakajima-Takenaka C, Zhang G-X, Obata K, Tohne K, Matsuyoshi H, Nagai Y, Nishiyama A, Takaki M.Left ventricular function of isoproterenol-induced hypertrophied rat hearts perfused with blood: mechanical work and energies.Am. J. Physiol. Heart. Circ. Physiol. 297:H1736-H1743, 2009
Yoshida A, Noda T, Tani M, Oyama T, Watanabe Y, Kiyomoto H, Nishiyama A.The role of basic fibroblast growth factor to enhance fetal intestinal mucosal cell regeneration in vivo.Pediatr. Surg. Int. 2009, Avgi 25(8):691-5. "
Du J, Fan Y-Y, Hitomi H, Kiyomoto H, Kimura S, Kong C-Z, Noma T, Kohno M, Nishiyama A, Nakano D.Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats.Am. J. Physiol. Renal Physiol. 2009 Sep;297(3):F802-8. Epub 2009 Jun 17
Nagai Y, Ichihara A, Nakano D, Kimura S, Pelisch N, Fujisawa Y, Hitomi H, Hosomi N, Kiyomoto H, Kohno M, Ito H, Nishiyama A.Possible contribution of the nonproteolytic activation of prorenin to the development of insulin resistance in fructose-fed rats.Exp. Physiol. 94:1016-1023,2009.
Fan Y, Kohno M, Nakano D, Hitomi H, Nagai Y, Fujisawa Y, Lu XM, Fu K, Du J, Ohmori K, Hosomi N, Kimura S, Kiyomoto H, Nishiyama.Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats.J Hypertension. 2009 Sep;27(9):1855-62.
Lu XM, Zhang GX, Yu YQ, Kimura S, Nishiyama A, Matsuyoshi H, Shimizu J, Takaki M.The opposite roles of nNOS in cardiac ischemia-reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice.J Physiol Sci. 2009 Jul;59(4):253-62.
Hobo A, Yuzawa Y, Kosugi T, Kato N, Asai N, Sato W, Maruyama S, Ito Y, Kobori H, Ikematsu S, Nishiyama A, Matsuo S, Kadomatsu K.The growth factor midkine regulates the renin-angiotensin system in mice.. Clin. Invest. 2009 Jun;119(6):1616-25.
Tsugita M, Iwasaki Y, Nishiyama M, Taguchi T, Shinahara M, Taniguchi Y, Kambayashi M, Nishiyama A, Gomez-Sanchez CE, Terada Y, Hashimoto K.Glucocorticoid receptor plays an indispensable role in mineralocorticoid receptor-dependent transcription in GR-deficient BE(2)C and T84 cells in vitro.Mol Cell Endocrinol. 2009 Apr 10;302(1):18-25.
J. Igarashi, K. Shoji, T. Hashimoto, T. Moriue, T. Takamura, K. Yoneda, T. Yamashita, Y. Kubota, H. Kosaka, Transforming Growth Factor-{beta}1 Down-Regulates Caveolin-1 Expression And Enhances Sphingosine 1-Phosphate Signaling In Cultured Vascular Endothelial Cells., Am. J. Physiol. (Cell Physiology), 297(5), (2009)C1263-C1274
T. Hashimoto, J. Igarashi, H. Kosaka, SPHINGOSINE KINASE IS INDUCED IN MOUSE 3T3-L1 CELLS AND PROMOTES ADIPOGENESIS, Journal of Lipid Research, 50(4), (2009)602-610
M. Murai, T. Yamashita, M. Senoh, Y. Mashimo, M. Kataoka, H. Kosaka, A. Matsuno-Yagi, T. Yagi, H. Miyoshi, Characterization of the ubiquinone binding site in the alternative NADH-quinone oxidoreductase of Saccharomyces cerevisiae by photoaffinity labeling. Biochemistry, 49(13) (2010) 2973-2980.
Jian G, Morishita A, Kurokohchi K, Tani J, Kato K, Miyoshi H, Inoue H, Kobayashi M, Shi L, Murota M, Muramatsu A, Izuishi K, Suzuki Y, Yoshida H, Uchida N, Deguchi K, Iwama H, Ishimaru I, Masaki T. Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer. Int J Oncol　36: 101-106, 2010"
Hiroko Abe, Yuki Takaoka, Yasunori Chiba, Natsuko Sato, Satoru Ohgiya, Akiko Itadani, Mitsuomi Hirashima, Chikashi Shimoda, Yoshifumi Jigami, Ken-ichi Nakayama. Development of valuable yeast strains using a novel mutagenesis technique for the effective production of therapeutic glycoproteins. Glycobiology 19 (4): 428-436, 2009
Tomohiro Arikawa, Akihiro Matsukawa, Kota Watanabe, Ken-mei Sakata, Masako Seki, Megumi Nagayama, Keisuke Takeshita, Kanako Ito, Toshiro Niki, Souichi Oomizu, Rika Shinonaga, Naoki Saita, Mitsuomi Hirashima. Galectin-9 accelerates transforming growth factor beta3-induced differentiation of human mesenchymal stem cells to chondrocytes. BONE, 44 (5): 849-857, 2009
Ai Matsuura, Junichi Tsukada, Takamitsu Mizobe, Takehiro Higashi, Fumihiko Mouri, Rena Tanikawa, Akira Yamauchi, Mitsuomi Hirashima, Yoshiya Tanaka. Intracellular galectin-9 activates inflammatory cytokines in monocytes. Genes to Cells 14 (4): 511-521, 2009
Haruna Niwa, Takahiro Satoh, Yuki Matsushima, Kazuki Hosoya, Kazumi Saeki, Toshiro Niki, Mitsuomi Hirashima, Hiroo Yokozeki. Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: a potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation. Clin. Immunol. 132 (2): 184-194, 2009
Haorile Chagan-Yasutan, Hiroki Saitoh, Yugo Ashino, Tomohiro Arikawa, Mitsuomi Hirashima, Shenwei Li, Motoki Usuzawa, Shigeru Oguma, Elizabeth Freda O. Telan, Chikwelu Larry Obi, Toshio Hattori. Persistent elevation of plasma osteopontin levels in HIV patients despite highly active antiretroviral therapy. Tohoku J. Exp. Med. 218 (4): 285-292, 2009
Tomohiro Arikawa, Kota Watanabe, Masako Seki, Akihiro Matsukawa, Souichi Oomizu, Ken-mei Sakata, Atsuko Sakata, Masaki Ueno, Naoki Saita, Toshiro Niki, Akira Yamauchi, Mitsuomi Hirashima. Galectin-9 ameliorates immune complex-induced arthritis by regulating FcgammaR expression on macrophages. Clin. Immunol. 133 (3): 382-392, 2009
Toshiro Niki, Shoko Tsutsui, Shigeru Hirose, Sachiko Aradono, Yasushi Sugimoto, Keisuke Takeshita, Nozomu Nishi, Mitsuomi Hirashima. Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation. J. Biol. Chem. 284 (47): 32344-32352, 2009
Wentao He, Zemin Fang, Feng Wang, Ke Wu, Yi Xu, Hongmin Zhou, Dunfeng Du, Ying Gao, Wei-Na Zhang, Toshiro Niki, Mitsuomi Hirashima, Jin Yuan, Zhonghua Klaus Chen. Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation 88 (6): 782-790, 2009
Arikawa T, Saita N, Oomizu S, Ueno M, Matsukawa A, Katoh S, Kojima K, Nagahara K, Miyake M, Yamauchi A, Kohrogi H, and Hirashima M. Galectin-9 expands immunosuppressive macrophages to ameliorate T cell-mediated lung inflammation. Eur. J. Immunol. 40(2): 548-558, 2010
有川智博、谷川令奈、平島光臣. Galectinをめぐって. Annual Review呼吸器2009, 13-18, 2009
大水総一，有川智博，加藤茂樹，山内清明，平島光臣. ガレクチン９による免疫制御. 臨床免疫・アレルギー科 51(5): 512-518, 2009
John A. Mengshol, Lucy Golden-Mason, Tomohiro Arikawa, Maxwell Smith, Toshiro Niki, Ryan McWilliams, Jessica Randall, Rachel McMahan, Manu Rangachari, Evgenia Dobrinskikh, Pierre Busson, Stephen J. Polyak, Mitsuomi Hirashima, Hugo R. Rosen. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in chronic hepatitis C infection. Plos One, in press, 2010
Shigeki Katoh, Atsuya Nobumoto, Nobuhiro Matsumoto, Kiyoshi Matsumoto, Naomi Ehara, Toshiro Niki, Hiroyuki Inada, Nozomu Nishi, Akira Yamauchi, Kiyoyasu Fukushima, Mitsuomi Hirashima. Involvement of galectin-9 in lung eosinophilia in patients with eosinophilic pneumonia. Int. Arch. Allergy Immunol. in press, 2010
Tsutomu Kobayashi, Junya Kuroda, Eishi Ashihara, Souichi Oomizu, Yasuhito Terui, Akiko Taniyama, Mio Yamamoto, Satoko Adachi, Tomohisa Takagi, Kiyohiko Hatake, Akira Yamauchi, Mitsuomi Hirashima, Masafumi Taniwaki. Galectin-9 exhibits anti-myeloma activity through JNK and p38 MAP kinase pathways. Leukemia in press, 2010
Rena Tanikawa, Takahisa Tanikawa, Mitsuomi Hirashima, Akira Yamauchi, Yoshiya Tanaka. Galectin-9 induces osteoblast differentiaion through the CD44/Smad signaling pathway. BBRC in press, 2010
Sharvan Sehrawat, Pradeepbabu J Reddy, Naveen Rajasagi, Amol Suryawanshi, Mitsuomi Hirashima, Baryy T Rouse. Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8+ T cell response. PLOS Pathogens in press, 2010
S. Taie, J. Ono, Y. Iwanaga, S. Tomita, T. Asaga, K. Chujo, M. Ueki, HIF-1α has a key role in hypoxic preconditioning, Journal of Clinical Neuroscience, Vol.16(2009) 1056-1060
K.Moriwaki,N.Miyashita,A.Mita,H.Gotho,K.Tsuchiya,H.Kato,K.Mekada,C.Noro,S.Oota,A.Yoshiki,Y.Obata,H. Yonekawa,T.Shiroishi,Unique inbred strain MSM/Ms established from the japanese wild mouse. Experimental Animals,Vol.58,No.2(2009)123-134
宮下信泉、久城憲壽、城石俊彦、松島芳文、山口泰典、佐藤淳、野生集団より新たに育成されたマウス系統の実験動物としての貢献（総論）。関西実験動物研究会会報31号49-54(H21/12)
Failure of d-psicose absorbed in the small intestine to metabolize into energy and its low large intestinal fermentability in humans.Metabolism 2009 Sep 16 Epub ahead of print. Iida T; Hayashi N; Yamada T; Yoshikawa Y; Miyazato S; Kishimoto Y; Okuma K; 徳田雅明; Izumori K Metabolism Epub ahead of print 2009.09"
Analysis of the inhibitory mechanism of D-allose on MOLT-4F leukemia cell proliferation.平田祐子; 斉藤まどか; 塚本郁子; 山口文徳; 隋麗; 神鳥和代; 董有毅; 徳田雅明 J Biosci Bioeng 2009 May;107(5):562-8."
Growth inhibition of head and neck carcinomas by D-allose.Mitani T; Hoshikawa H; Mori T.; Hosokawa T.; Tsukamoto I; Yamaguchi F; Kamitori K; Tokuda M; Mori N , Head Neck. 2009 Aug;3131(8):1049-55"
Expression pattern and role of galectin-1 during early mouse myogenesis. Dev.Growth.Differ. (2009), 51,607-615: H. Shoji, L. Deltour, T. Nakamura, S. Tajbakhsh & F. Poirier.
Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. Glycobiology (2009), 19,112-117: H. Nagae, N. Nishi, T. Murata, T. Usui, T. Nakamura, S. Wakatsuki & R. Kato

Song T, Hatano N, Kambe T, Miyamoto Y, Ihara H, Yamamoto H, Sugimoto K, KumeK, Yamaguchi F, Tokuda M, Watanabe Y. Nitric oxide-mediated modulation of calcium/calmodulin-dependent protein kinase II.Biochem J. (2008) in press.
Fujimoto T, Yurimoto S, Hatano N, Nozaki N, Sueyoshi N, Kameshita I, Mizutani A, Mikoshiba K, Kobayashi R, Tokumitsu H. Activation of SAD Kinase by Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase. Biochemistry. (2008) 47(13):4151-9.
Tanaka H, Tamai E, Miyata S, Taniguchi Y, Nariya H, Hatano N, Houchi H, Okabe A. Construction and characterization of a clostripain-like protease-deficient mutant of Clostridium perfringens as a strain for clostridial gene expression. Appl Microbiol Biotechnol. (2008) 77(5):1063-71.
Nakai K, Yoneda K, Moriue T, Matsuoka Y, Yokoi I, Nibu N and Kubota Y: Fabry disease masquerading as multiple leg ulcers. J Eur Acad Dermatol and Venereol 22: 382-383, 2008
Moriue T, Igarashi J, Yoneda K, Nakai K, Kosaka H and Kubota Y: Sphingosine-1-phosphate attenuates H2O2-induced apoptosis in cultured vascular endothelial cells: roles of caspase-3 and p38 MAP kinase. Biochem Biophys Res Commun 368: 852-857, 2008
Yoneda K, Demitsu T, Matsuda Y and Kuboata Y: Possible molecular mechanisms for sebaceous hyperplasia overlying dermatofibroma. Br J Dermatol 158: 840-842, 2008
Yoneda K, Demitsu T, Matsuoka Y, Moriue T, Nakai K, Kushida Y, Haba R and Kubota Y: Subcellular activation site of caspase 3 in apoptotic keratinocytes observed in lichenoid tissue reaction. Br J Dermatol 158: 1166-1168, 2008
Nakai K, Yoneda K, Moriue T, Kosaka H and Kubota Y: Angiotensin II enhanced cell proliferation and EGF receptor expressioin levels via ROS fomation in HaCaT cells. J Dermatol Sci. 51(3):181-9, 2008
Arif-Ul Hasan, Setsuo Suguri, Chigusa Fujimoto, Rodney Londari Itaki, Masakazu Harada, Masato Kawabata, Hugo Bugoro, Bobogare Albino, Takahiro Tsukahara, Francis Hombhanje and Andrew Masta. 2008. Phylogeography and dispersion pattern of Anopheles farauti senso stricto mosquitoes in Melanesia. Molecular Phylogenetics and Evolution, 46(2), 792-800.
Murao K, Yu X, Imachi H, Cao WM, Chen K, Matsumoto K, Nishiuchi T, Wong NC, Ishida T. Hyperglycemia suppresses hepatic scavenger receptor class B type I expression. Am J Physiol Endocrinol Metab. Jan;294(1):E78-87, 2008
Murao K, Imachi H, Yu X, Cao WM, Nishiuchi T, Chen K, Li J, Ahmed RA, Wong NC, Ishida T. Interferon-alpha decreases expression of human scavenger receptor class BI, possible HCV receptor in hepatocytes. GUT. 2008 May;57:664-71
Rieko Goto, Hiroshi Hoshikawa, Takashi Fujii, Kanako Indo, Kunitoshi Yoshino, Katsumi Imaida, Nozomu Mori Clinicopathological significance of cyclooxygenase-2 expression in hypopharyngeal squamous cell carcinoma Oncology Reports, 19,645-650,2008
Wang J, Okamoto Y, Tsuboi K, Ueda N, The stimulatory effect of phosphatidylethanolamine on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD). Neuropharmacology 54:8-15, 2008
Wang J, Ueda N, Role of the endocannabinoid system in metabolic control. Curr Opin Nephrol Hypertens 17:1-10, 2008
H. Yamamoto, N. Nishi, H. Shoji, A. Ito, L.-H. Lu, M. Hirashima & T. Nakamura. Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T cells. J. Biochem., 143,311-324 (2008)
M. Nagae, N. Nishi, S. Nakamura-Tsuruta, J. Hirabayashi, S. Wakatsuki & R. Kato: Structural Analysis of the Human Galectin-9 N-terminal Carbohydrate Recognition Domain Reveals Unexpected Properties that Differ from the Mouse Orthologue. J. Mol. Biol., 375, 119-135 (2008)
Iwanaga Y, Ueno M, Ueki M, Huang CL, Tomita S, Okamoto Y, Ogawa T, Ueda N, Maekawa N, Sakamoto H: The expression of osteopontin is increased in vessels with blood-brain barrier impairment, Neuropathol Appl Neurobiol, 34:145-54, 2008
Tetsuya Moriue, Junsuke Igarashi, Kozo Yoneda, Kozo Nakai, Hiroaki Kosqaka, Yasuo Kubota. Sphinosine 1-phosphate attenuates H2O2-induced apoptosis in endothelial cells. BBRC 368(2008) 852-857
Masako Seki, Souichi Oomizu, Ken-mei Sakata, Atsuko Sakata, Tomohiro Arikawa, Kota Watanabe, Kanako Ito, Keisuke Takeshita, Toshiro Niki, Naoki Saita, Nozomu Nishi, Akira Yamauchi, Shigeki Katoh, Akihiro Matsukawa, Vijay Kuchroo, Mitsuomi Hirashima. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin. Immunol. 127: 78-88. 2008
Hitomi Yamamoto, Nozomu Nishi, Hiroki Shoji, Aiko Itoh, Liang-Hao Lu, Mitsuomi Hirashima, Takanori Nakamura. Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T cells. The Journal of Biochemistry. 143(3): 311-324. 2008
Rena Tanikawa, T. Tanikawa, Y Okada, K Nakano, Mitsuomi Hirashima, Akira Yamauchi, R Hosokawa, Y Tanaka.. Interaction of galectin-9 with lipid rafts induces osteoblast proliferation through c-Src/ERK signaling pathway. J Bone and Mineral Res. 23(2): 278-286. 2008
Yamaguchi F, Takata M, Kamitori K, Nonaka M, Dong Y, Sui L, Tokuda M. Rare sugar D-allose induces specific up-regulation of TXNIP and subsequent G1 cell cycle arrest in hepatocellular carcinoma cells by stabilization of p27kip1. Int J Oncol. 2008 Feb;32(2):377-85
Nishiyama A, Nakagawa T, Kobori H, Nagai Y, Okada N, Konishi Y, Morikawa T, Okumura M, Meda I, Kiyomoto H, Hosomi N, Mori T, Ito S, Imanishi M.Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria.J Hypertens. 2008 Sep;26(9):1849-1859
Yasuyuki Iwanaga, Masaki Ueno, Masaaki Ueki, Cheng-long Huang, Shuhei Tomita, Yasuo Okamoto, Takafumi Ogawa, Natsuo Ueda, Nabuhiro Maekawa, Haruhiko Sakamoto. The expression of osteopontin is increased in vessels with blood-brain barrier impairment. Neuropathology and Applied Neurobiology 2008; 34, 145-154
Imaizumi T, Arikawa T, Sato T, Uesato R, Matsumiya T, Yoshida H, Ueno M, Yamasaki S, Nakajima T, Hirashima M, Sakata K, Ishibashi Y, Toh S, Ohyama C, Satoh K. Involvement of retinoic acid-inducible gene I (RIG-I) in inflammation of rheumatoid fibroblast-like synoviocytes. Clin Exp Immunol, 2008; 153, 240-244
Akiyama Kosuke, Miyashita Takenori, Mori Terushige, Inamoto Ryuhei, Mori Nozomu. Expression of thiazide-sensitive Na+-Cl- cotransporter in the rat endolymphatic sac. BBRC 2008; 371,649-653
Akiyama Kosuke, Miyashita Takenori, Matsubara Ai, Mori Terushige, Inamoto Ryuhei, Nishiyama Akira, Mori Nozomu. A new approach for selective rat endolymphatic sac epithelium collection to obtain pure specific RNA. BBRC 2008; 376,611-614
Mohammad SH, Kurokohchi K, Yoneyama H, Tokuda M, Morishita A, Jian G, Shi L, Murota M, Tani J, Kato K, Miyoshi H, Deguchi A, Himoto T, Usaki H, Wakabayashi H, Izuishi K, Suzuki Y, Iwama H, Deguchi K, Uchida N, Sabet AE, Arafa AU, Hassan AA, El-Sayed AA, Masaki T. Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma. Int J Oncol 2008; 33: 1157-1163
Wang J, Zhao L-Y, Uyama T, Tsuboi K, Wu X-X, Kakehi Y, Ueda N, Expression and secretion of N-acylethanolamine-hydrolyzing acid amidase in human prostate cancer cells. J Biochem 2008; 144:685-690
Wang J, Zhao L-Y, Uyama T, Tsuboi K, Tonai T, Ueda N, Amino acid residues crucial in pH regulation and proteolytic activation of N-acylethanolamine-hydrolyzing acid amidase. Biochim Biophys Acta-Mol Cell Biol Lipids 2008; 1781:710-717
Satoshi Taie, Masaaki Ueki, Kosuke Chujo, Takehiko Asaga, Yasuyuki Iwanaga , Junichiro Ono, Nobuhiro Maekawa. Urinary trypsin inhibitor ameliorates renal tissue oxygenation after ischemic reperfusion in rats, Journal of Anesthesia, 2008;22:149-54.
Ueki M, Asaga T, Chujo K, Ono J, Iwanaga Y, Taie S. D-allose protects against endotoxemic acute renal injury. J Biosci Bioeng 2008;105:481-5.
K.Chujo; M.Ueki; T.Asaga; S.Taie. The Atrial Natriuretic Peptide Attenuates Ischemia/Reperfusion-Induced Renal Injury by Reducing Neutrophil Activation in Rats. Tohoku Journal of Experimental Medicine 2008;215:257-266
Takehiko Asaga; Masaaki Ueki; Kousuke Chujo; Satoshi Taie. JTE-607, An Inflammatory Cytokine Synthesis Inhibitor, Attenuates Ischemia /Reperfusion-Induced Renal Injury by Reducing Neutrophil Activation in Rats. JOURNAL OF BIOSCIENCE AND BIOENGINEERING 2008;106:22-26
Masaaki Ueki; Takehiko Asaga; Kousuke Chujo; Junichiro Ono; Yasuyuki Iwanaga; Satoshi Taie. D-allose protects against endotoxemic acute renal injury. Journal of bioscience and bioengineering 2008;105:481-485
Nishi N, Abe A, Iwaki J, Yoshida H, Itoh A, Shoji H, Kamitori S, Hirabayashi J, Nakamura T. Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1. Glycobiology. 2008; 18(12):1065-1073
Iwaki J, Minamisawa T, Tateno H, Kominami J, Suzuki K, Nishi N, Nakamura T, Hirabayashi J. Desulfated galactosaminoglycans are potential ligands for galectins: evidence from frontal affinity chromatography. Biochem Biophys Res Commun. 2008; 373(2):206-212
Nishi N, Shoji H, Miyanaka H, Nakamura T. Transient up-regulation of a novel member of Spot 14 family in androgen-stimulated rat prostate. Biochim Biophys Acta. 2008;1780(7-8):1004-9
Yamamoto H, Nishi N, Shoji H, Itoh A, Lu LH, Hirashima M, Nakamura T. Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T-cells. J Biochem. 2008; 143(3):311-24
Miki T, Yokoyama T, Sumitani K, Kusaka T, Warita Y, Matsumoto Y, Wang ZY, Wilce PA, Bedi KS, Itoh, S, Takeuchi Y. Ethanol neurotoxicity and dentate gyrus development. Congenital Anomalies 2008; Sep; 48(3):110-117
Miki T, Kuma H, Yokoyama Y, Sumitani K, Matsumoto Y, Kusaka T, Warita K, Wang ZY, Hosomi N, Imagawa T, Bedi KS, Itoh S, Nakamura Y, Takeuchi Y. Early postnatal ethanol exposure induces fluctuation in the expression of BDNF mRNA in the developing rat hippocampus. Acta Neurobiol Exp 2008; 68(4): 484-493
Masako Seki, Souichi Oomizu, Ken-mei Sakata, Atsuko Sakata, Tomohiro Arikawa, Kota Watanabe, Kanako Ito, Keisuke Takeshita, Toshiro Niki, Naoki Saita, Nozomu Nishi, Akira Yamauchi, Shigeki Katoh, Akihiro Matsukawa, Vijay Kuchroo, Mitsuomi Hirashima. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin. Immunol.2008; 127(1): 78-88
Meiyan Liang, Masaki Ueno, Souichi Oomizu, Tomohiro Arikawa, Rika Shinonaga, Shulan Zhang, Akira Yamauchi, Mitsuomi Hirashima. Galectin-9 expression links to malignant potential of cervical squamous cell carcinoma. J. Cancer Res. Clin. Oncol. 2008; 134(8): 899-907
Tadaatsu Imaizumi, Tomohiro Arikawa, Tomoo Sato, Ryoko Uesato, Tomoh Matsumiya, Hidemi Yoshida, Masaki Ueno, Satoshi Yamasaki,Toshihiro Nakajima, Mitsuomi Hirashima, Ken-mei Sakata, Yasuyuki Ishibashi, Satoshi Toh, Chikara Ohyama, Kei Satoh. Involvement of retinoic acid-inducible gene-I in inflammation of rheumatoid fibroblast-like synoviocytes. Clin. Exp. Immunol. 2008; 153: 240-244
Shoko Makishi, Taeko Okudaira, Chie Ishikawa, Shigeki Sawada, Toshiki Watanabe, Mitsuomi. A modified version of galectin-9 induces cell cycle arrest and apoptosis of Burkitt and Hodgkin lymphoma cells. Brit. J. Haematol. 2008; 142: 583-594
Atsuya Nobumoto, Keiko Nagahara, Souichi Oomizu, Shigeki Katoh, Nozomu Nishi, Keisuke Takeshita, Toshiro Niki, Akira Tominaga, Akira Yamauchi, Mitsuomi Hiirashima. Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices. Glycobiology 2008; 18(9): 735-744
Keiko Nagahara, Tomohiro Arikawa, Souichi Oomizu, Keiichi Kontani, Atsuya Nobumoto, Hiroaki. Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells, and enhances antitumor immunity. J. Immunol. 2008; 181 (11): 7660-7669
S. Sehrawat, A. Suryawanshi, M. Hirashima, B.T. Rouse. Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators. J. Immunol. 2008; 182 (5): 3191-3201
山内清明、大水総一、有川智博、加藤茂樹、法村尚子、村澤千沙、紺谷桂一、平島光臣ガレクチン９によるIL-17の制御とその意義臨床免疫・アレルギー科 2008; 49 (6): 690-697
Yokohira M, Takeuchi H, Saoo K, Matsuda Y, Yamakawa K, Hosokawa K, Kuno T, Imaida K. Establishment of a bioassay model for lung cancer chemoprevention initiated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in female A/J mice. Exp. Toxicol. Pathol.2008; 60: 469-473
Yamaguchi F, Takata M, Kamitori K, Nonaka M, Dong Y, Sui L, Tokuda M. Rare sugar D-allose induces specific up-regulation of TXNIP and subsequent G1 cell cycle arrest in hepatocellular carcinoma cells by stabilization of p27kip1. Int J Oncol. 2008 ;32(2):377-85
Miyanishi N, Sato N, Nakakita S, Sumiyoshi W, Morimoto K, Okuma H, Tokuda M, Izumori K, Watanabe E, Hirabayashi J. Development of an amperometric flow analysis sensor for specific detection of D-psicose. Biosens Bioelectron. 2008;23(9):1347-52.
Song T, Hatano N, Kambe T, Miyamoto Y, Ihara H, Yamamoto H, Sugimoto K, Kume K, Yamaguchi F, Tokuda M, Watanabe Y. Nitric oxide-mediated modulation of calcium/calmodulin-dependent protein kinase II. Biochem J. 2008;412(2):223-31
Shimamoto S, Takata M, Tokuda M, Oohira F, Tokumitsu H, Kobayashi R. Interactions of S100A2 and S100A6 with the Tetratricopeptide Repeat Proteins, Hsp90/Hsp70-organizing Protein and Kinesin Light Chain. J Biol Chem. 2008;283(42):28246-28258
Yamaguchi F, Kamitori K, Sanada K, Horii M, Dong Y, Sui L, Tokuda M. Rare sugar d-allose enhances anti-tumor effect of 5-fluorouracil on the human hepatocellular carcinoma cell line HuH-7. J Biosci Bioeng. 2008;106(3):248-52
Du Y, Hirooka K, Miyamoto O, Itano T, Tokuda M, Shiraga F. Both amacrine and bipolar cells release glutamate in the rat retina after ischemia/reperfusion insult in vitro. Curr Eye Res. 2008;33(9):782-8
Mohammad HS, Kurokohchi K, Yoneyama H, Tokuda M, Morishita A, Jian G, Shi L, Murota M, Tani. Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma. Int J Oncol. 2008;33(6):1157-63
徳田雅明、山口文徳、松尾達博、木村正司、大森浩二、村尾孝児、板野俊文、隋麗希少糖の医薬品への応用可能性 2008　第86巻　第9号　
Kenji Kitaizumi, MD; Kazushi Yukiiri, MD; Hisashi Masugata, MD; Kaori Shinomiya, MD; Minako Ohara, MD; Hiroyuki Takinami, MD; Yasuyoshi Iwado, MD; Junji Yoshida, MD; Takahisa Noma, MD; Koji Ohmori, MD; Yoichi Yamashita, MD; Taiko Horii, MD; Shoichi Senda, MD; Masakazu Kohono, MD. Positron Emission Tomographic Demonstration of Myocardial Oxidative Metabolism in a Case of Left Ventricular Restoration After Cardiac. Resynchronization Therapy. Circulation Jouranal. 2008; 72(11); 1900-1903

Demitsu T, Yoneda K, Umemoto N, Azuma R, Kakurai M, Nishida J, Sadahira C and Kubota Y: Agminated mollusca contagiosa with attenuated ubiquitination of molluscum bodies as an initial sign of malignant lymphoma. J Eur Acad Dermatol and Venereol 21: 691- 692, 2007
Matsuoka Y, Yoneda K, Katsuura J, Moriue T, Nakai K, Sadahira C, Yokoi I, Nibu N, Demitsu T and Kubota Y: Successful treatment of follicular cutaneous T-cell lymphoma without mucinosis treated with narrow-band UVB irradiation. J Eur Acad Dermatol and Venereol 21: 1121-1122, 2007
Yoneda K, Bandoh S, Kanaji N, Moriue T, Katsuura J, Matsuoka Y, Nakai K, Demitsu T, Ishida T and Kubota Y: Eosinophilic pustular folliculits associated with pulmonary infiltration with eosinophilia. J Eur Acad Dermatol and Venereol 21: 1122- 1124, 2007
Moriue T, Yoneda K, Katsuura J, Matsuoka Y, Nakai K, Yokoi I, Matsuda Y, Nibu N, Miyamoto I, Demitsu T and Kubota Y: Planar xanthomas due to cholestasis in graft versus host disease. Br J Dermatol 156: 1374-1376, 2007
Yoneda K, Katsuura J, Matsuoka Y, Moriwaki S, Moriue T, Nakai K, Yokoi I, Nibu N, Demitsu T and Kubota Y: Xeroderma pigmentosum group G in association with malignant melanoma. Eur J Dermatol 17: 540-541, 2007
Yoneda K, Yokoi I, Demitsu T, Matsuda Y, Matsuoka Y, Miyamoto I, Moriue T, Nakai K, Nibu N, Hashimoto T and Kubota Y: Linear IgA bullous disease showing insect bite-like eruption. Eur J Dermatol 17: 340-341, 2007
Kakurai M, Demitsu T, Azuma R, Yamada T, Suzuki M, Yoneda K, Ishii N and Hashimoto T: Localized pemphigoid (pretibial type) with IgG antibody to BP180 NC16a domain successfully treated with minocycline and topical corticosteroid. Clin Exp Dermatol 32: 759-761, 2007
Fusumada K, Yokoyama T, Miki T, Wang ZY, Yang W, Lee NS, Endo Y, Takeuchi Y. c-Fos expression in the periaqueductal gray is induced by electroacupuncture in the rat, with possible reference to GABAergic neurons. Okajimas Folia Anat Jpn. 2007 May;84(1):1-9
Nakai K, Yoneda K, Moriue T, Kosaka H and Kubota Y: Angiotensin II enhanced cell proliferation and EGF receptor expressioin levels via ROS fomation in HaCaT cells. J Dermatol Sci in press
Yoshida, H., Yamada, M., Nishitani, T., Takada, G., Izumori, K. & Kamitori, S. (2007). Crystal structures of D-tagatose 3-epimerase from Pseudomonas cichorii and its complexes with D-tagatose and D-fructose. J. Mol. Biol. 374(2), 443-453.
Miki T, Yokoyama T, Sumitani K, Wang ZY, Yang W, Kusaka T, Matsumoto Y, Warita K, Lee NS, Fukui Y, Takeuchi Y. The effect of prenatal X-irradiation on the developing cerebral cortex of rats. II: A quantitative assessment of glial cells in the somatosensory cortex. Int J Dev Neurosci. 2007 Aug;25(5):293-7
Masakazu Harada, Pusadee Sri-aroon, Chantima Lohachit, Chigusa Fujimoto, Arif-Ul- Hasan, Rodney Itaki, Setsuo Suguri, Yupa Chusongsang and Phiraphol Chusongsang. 2007. Intertidal snail-trematode communities on the southern Thailand before and after the South Asia tsunami. Southeast Asian J. Trop. Med. Public Health, 38 (4), 658-662.
影井昇, 原田正和, 村主節雄. 2007. 香川大学医学部国際医動物学教室に鑑別を依頼された眼虫属線虫類について（附、我が国におけるヒト眼虫症感染の現状について）. Clinical Parasitology, 18(1), 14-17.
原田正和・村主節雄. 干潟の巻貝類に寄生する吸虫類幼生. 兵庫陸水生物, 59, 1-14. 2007.
Murao K, Imachi H, Yu X, Cao WM, Nishiuchi T, Chen K, Li J, Ahmed RA, Wong NC, Ishida T. Interferon-? decreases expression of human scavenger receptor class BI, possible HCV receptor in hepatocytes. GUT. 2007 Oct 23 (in press)
Yoshida K, Murao K, Imachi H, Cao WM, Yu X, Li J, Ahmed RA, Kitanaka N, Wong NCW, Unterman TG, Magnuson MA, Ishida T. Pancreatic Glucokinase is Activated by Insulin-like Growth Factor-I Endocrinology Jun;148(6):2904-13, 2007
Yu X, Murao K, Imachi H, Cao WM, Li J, Matsumoto K, Nishiuchi T, Ahmed RAM, Wong NCW, Kosaka H, Unterman TG, Ishida T. Regulation of scavenger receptor class BI gene expression by angiotensin II in vascular endothelial cells. Hypertension Jun;49(6):1378-84, 2007
Murao K, Yu X, Cao WM, Imachi H, Chen K, Muraoka T, Kitanaka N, Li J, Ahmed RA, Matsumoto K, Nishiuchi T, Tokuda M, Ishida T. D-Psicose inhibits the expression of MCP-1 induced by high-glucose stimulation in HUVECs. Life Sci. Jul 26;81(7):592-9, 2007
Miyashita Takenori, Tatsumi Hiroshi, Hayakawa Kimihide, Mori Nozomu, Sokabe Masahiro Large Na+ influx and high Na+,K+,-ATPase activity in mitochondria-rich epithelial cells of the inner ear endolymphatic sac Pflugers Arch Eur J Physiol, 453,905-913,2007
Kosuke Akiyama, Takenori Miyashita, Terushige Mori, Nozomu Mori Expression of the Na+-,K+-2Cl- cotransporter in the rat endolymphatic sac BBRC, 364,913-917,2007
Miyake Y, Ohmori K, Yoshida J, Ishizawa M, Mizukawa M, Yukiiri K, Kohno M. Granulocyte colony-stimulating factor facilitates the angiogenesis induced by ultrasonic microbubble destruction. Ultrasound Med Biol. 2007 Nov;33(11):1796-804. Epub 2007 Aug 8.
Hosomi N, Ohyama H, Ichihara S, Takahashi T, Naya T, Kohno M. Relation of postischemic delayed hypoperfusion and cerebral edema after transient forebrain ischemia. J Stroke Cerebrovasc Dis. 2007 May-Jun;16(3):103-8
Tsuboi K, Takezaki N, Ueda N, The N-acylethanolamine-hydrolyzing acid amidase(NAAA). Chem Biodivers 4(8):1914-1925, 2007
Okamoto Y, Wang J, Morishita J, Ueda N, Biosynthetic pathways of the endocannabinoid anandamide. Chem Biodivers 4(8):1842-1857, 2007
Jin X-H, Okamoto Y, Morishita J, Tsuboi K, Tonai T, Ueda N, Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners. J Biol Chem 282:3614-3623, 2007
Tsuboi K, Zhao L-Y, Okamoto Y, Araki N, Ueno M, Sakamoto H, Ueda N, Predominant expression of N-acylethanolamine-hydrolyzing acid amidase in macrophages revealed by immunochemical studies. Biochim Biophys Acta - Mol Cell Biol Lipids, 1771:623-632, 2007
Zhao L-Y, Tsuboi K, Okamoto Y, Nagahata S, Ueda N, Proteolytic activation and glycosylation of N-acylethanolamine-hydrolyzing acid amidase, a lysosomal enzyme involved in the endocannabinoid metabolism. Biochim Biophys Acta - Mol Cell Biol Lipids, 1771(11):1397-1405, 2007.11
Tsuboi K, Molecular characterization of a novel lysosomal enzyme degrading the anti-inflammatory lipid mediator N-acylethanolamine. Inflammation and Regeneration 27:18-27, 2007
坪井一人，上田夏生，エンドカンナビノイドの生理的機能と生合成・分解. 細胞工学 26:1264-1268, 2007
Zhang GX, Ohmori K, Nagai Y, Fujisawa Y, Nishiyama A, Abe Y, Kimura S. Role of AT1 receptor in isoproterenol-induced cardiac hypertrophy and oxidative stress in mice. J Mol Cell Cardiol. 2007 Apr;42(4):804-11.
Fujisawa Y, Nagai Y, Miyatake A, Miura K, Nishiyama A, Kimura S, Abe Y. Effects of adrenomedullin 2 on regional hemodynamics in conscious rats. Eur J Pharmacol. 2007 ;558(1-3):128-32.
Zhang GX, Nagai Y, Nakagawa T, Miyanaka H, Fujisawa Y, Nishiyama A, Izuishi K, Ohmori K, Kimura S. Involvement of endogenous nitric oxide in angiotensin II-induced activation of vascular mitogen-activated protein kinases. Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2403-8
T. Imaizumi, H. Yoshida, N. Nishi, H. Sashinami, T. Nakamura, M. Hirashima, C. Ohyama, K. Itoh & K. Satoh: Double-stranded RNA induces galectin-9 in vascular endothelial cells: Involvement of TLR3, P13K, and IRF3. Glycobiology, 17, 12C-15C (2007)
Y. Tsuboi, H. Abe, R. Nakagawa, S. Oomizu, K. Watanabe, N. Nishi, T. Nakamura, A. Yamauchi & M. Hirashima: Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes. Clin. Immunol., 124, 221-233 (2007)
H. Yamamoto, Y. Kashio, H. Shoji, R. Shinonaga, T. Yoshimura, N. Nishi, T. Nabe, T. Nakamura, S. Kohno & M. Hirashima: Involvement of galectin-9 in guinea pig allergic airway inflammation. Int. Arch. Allergy　Immunol., 143 (suppl 1), 95-105 (2007)
N. Miyanishi, N. Nishi, H. Abe, Y. Kashio, R. Shinonaga, S. Nakakita, W. Sumiyoshi, A. Yamauchi, T. Nakamura, M. Hirashima & J. Hirabayashi: Carbohydrate-recognition domains of galectin-9 are involved in intermolecular interaction with galectin-9 itself and other members of the galectin family. Glycobiology, 17, 423-432 (2007)
M. Seki, K. Sakata, S.Oomizu, T. Arikawa, A. Sakata, M. Ueno, A. Nobumoto, T. Niki, N. Saita, K. Ito, S. Dai, S. Katoh, N. Nishi, M. Tsukano, K. Ishikawa, A. Yamauchi, V. Kuchroo, & M. Hirashima: Beneficial effect of galectin 9 on rheumatoid arthritis by induction of apoptosis of synovial fibroblasts. Arthritis Rheum., 56, 3968-3976 (2007)
S. Katoh, N. Ishii, A. Nobumoto, K. Takeshita, S.Y. Dai, R. Shinonaga, T. Niki, N. Nishi, A. Tominaga, A. Yamauchi & M. Hirashima: Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma.Am. J. Respir. Crit. Care Med., 176, 27-35 (2007)
Masaaki Ueki, Satoshi Taie, Kousuke Chujo, Takehiko Asaga, Yasuyuki Iwanaga, Nobuhiro Maekawa: Inhibitory Effect of D-Allose on Neutrophil Activation after Rat Renal Ischemia/Reperfusion, Journal of Bioscience and Bioengineering, 104:304-308, 2007
Masaaki Ueki, Satoshi Taie, Kousuke Chujo, Takehiko Asaga, Yasuyuki Iwanaga, Junichiro Ono, Nobuhiro Maekawa: Urinary Trypsin Inhibitor Reduces Inflammatory Response in Kidney Induced by Lipopolysaccharide, Journal of Bioscience and Bioengineering, 104:315-320, 2007
Okamoto Y, Wang J, Morishita J, Ueda N: Biosynthetic pathways of the endocannabinoid anandamide, Chem Biodivers , 4:1842-1857, 2007
Jin X-H, Okamoto Y, Morishita J, Tsuboi K, Tonai T, Ueda N: Discovery and characterization of a Ca2+-independent phosphatidylethanolamine N-acyltransferase generating the anandamide precursor and its congeners, J Biol Chem , 282:3614-3623 , 2007
M. Jamal, K. Ameno, S. Ameno, J. Morishita, W. Wang, M. Kumihashi, U. Ikuo, T. Miki, and I. Ijiri: Changes in cholinergic function in the frontal cortex and hippocampus of rat exposed to ethanol and acetaldehyde, Neuroscience, 144: 232-238, 2007
Liang-Hao Lu, Ryusuke Nakagawa, Yumiko Kashio, Aiko Ito, Hiroki Shoji, Nozomu Nishi, Mitsuomi Hirashima, Akira Yamauchi, Takanori Nakamura. Characterization of galectin-9-induced death of Jurkat T cells. J. Biochemistry. 141(2): 157-172, 2007
Hitomi Yamamoto, Yumiko Kashio, Hiroki Shoji, Rika Shinonaga, Teizo Yoshimura, Nozomu Nishi, Takeshi Nabe, Takanori Nakamura, Shigekatsu Kohno, Mitsuomi Hirashima. Involvement of galectin-9 in guinea pig allergic airway inflammation. Int. Arch. Allergy Immunol. 143 (suppl 1): 93-103. 2007
Miyanishi N, Nishi N, Abe H, Kashio Y, Shinonaga R, Nakakita SI, Sumiyoshi W, Yamauchi A, Nakamura T, Hirashima M, Hirabayashi J. Carbohydrate-recognition domains of galectin-9 are involved in intermolecular interaction with galectin-9 itself and other members of the galectin family. Glycobiology. 17(4): 423-432. 2007
Shigeki Katoh, Naoki Ishii, Atsuya Nobumoto, Keisuke Takeshita, Shu-Yan Dai, Rika Shinonaga, Toshiro Niki, Nozomu Nishi, Akira Tominaga, Akira Yamauchi, Mitsuomi Hirashima. Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma. AJRCCM 176(1): 27-35. 2007
Yuka Tsuboi, Hiroko Abe, Ryusuke Nakagawa, Souichi Oomizu, Kota Watanabe, Nozomu Nishi, Takanori Nakamura, Akira Yamauchi, Mitsuomi Hirashima. Galectin-9 protects mice from Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes. Clin. Immunol. 124 (2): 221-233. 2007
Tadaatsu Imaizumi, Hidemi Yoshida, Nozomu Nishi, Hiroshi Sashinami, Takanori Nakamura, Mitsuomi Hirashima, Chikara Ohyama, Ken Itoh, Kei Satoh. Double-stranded RNA induces galectin-9 in vascular endothelial cells: involvement of TLR3, PI3K and IRF3 pathway. Glycobiology 17(7): 12C-15C. 2007
G.A. Rabinovich, F.-T. Liu, M. Hirashima, A. Anderson. An emerging role for galectins in tuning the immune response: lessons from experimental models of inflammatory disease, autoimmunity and cancer. Scandinavian Journal of Immunology. 66: 143-158. 2007
Okudaira T, Hirashima M, Ishikawa C, Makishi S, Tomita M, Matsuda T, Kawakami H, Taira N, Ohshiro K, Masuda M, Takasu N, Mori N. A modified version of galectin-9 suppresses cell growth and induces apoptosis of human T-cell leukemia virus type I-infected T-cell lines. Int J Cancer. 120(10): 2251-2261. 2007
Ana C. Anderson, David E. Anderson, Lisa Bregoli, William D Hastings, Nasim Kassam, Charles Lei, Rucha Chandwaskar, Jozsef Karman, Ee W Su, Mitsuomi Hirashima, Jeffrey N. Bruce, Lawrence P. Kane, Vijay K. Kuchroo, David A. Hafler. Promotion of tissue inflammation by the immune receptor TIM-3 expressed on innate immune cells. Science. 318: 1141-1143. 2007
SEKI, Masako; SAKATA, Ken-mei; OOMIZU, Souichi; ARIKAWA, Tomohiro; SAKATA, Atsuko; UENO, Masaki; NOBUMOTO, Atsuya; NIKI, Toshiro; SAITA, Naoki; ITO, Kanako; DAI, Shu-Yan; KATOH, Shigeki; NISHI, Nozomu; TSUKANO, Michishi; ISHIKAWA, Kouichiro; YAMAUCHI, Akira; KUCHROO, Vijay; HIRASHIMA, Mitsuomi. Beneficial effect of galectin-9 on rheumatoid arthritis by inducing apoptosis of synovial cells. Arthritis and Rheumatism. 56(12): 3968-3976. 2007
Julia F Pielage, Christoph Cichon, Lilo Greune, Mitsuomi Hirashima, Torsten Kucharzik, M. Alexander Schmidt. Reversible differentiation of Caco-2 cells reveals galectin-9 as a surface marker molecule for human follicle-associated epithelia and M cell-like cells. Int J Biochem Cell Biol. 39: 1886-1901. 2007
Shigeru Suna, Fuminori Yamaguchi, Shoji Kimura, Masaaki Tokuda and Fumihiko Jitsunari. Preventive effect of d-psicose, one of rare ketohexoses, on di-(2-ethylhexyl) phthalate (DEHP)-induced testicular injury in rat. Toxicology Letters. September 2007, Pages 107-117
Li Sui, Rika Nomura, Youyi Dong, , Fuminori Yamaguchi, Ken Izumori and Masaaki Tokuda, Cryoprotective effects of d-allose on mammalian cells. Cryobiology. Oct;55(2):87-92.
Song T, Sugimoto K, Ihara H, Mizutani A, Hatano N, Kume K, Kambe T, Yamaguchi F, Tokuda M, Watanabe Y. p90 RSK-1 associates with and inhibits neuronal nitric oxide synthase. Biochem J. Jan 15;401(2):391-8.
Tukamoto I、Konishi R,　Kubota Y,　Tokuda M, Sakakibara N, Maruyama T. Anti-angiogenic activities of nucleosides and nucleotides and their structure-activity relationship. Nucleic Acids Symp Ser (51):437-8.
Murao K, Yu X, Cao WM, Imachi H, Chen K, Muraoka T, Kitanaka N, Li J, Ahmed RA, Matsumoto K, Nishiuchi T, Tokuda M, Ishida T. D-Psicose inhibits the expression of MCP-1 induced by high-glucose stimulation in HUVECs. Life Sci. Jul 26;81(7):592-9. Epub 2007 Jul 3.

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