Prof. HIKANO

• Professor
  • Katsuya HIRANO, M.D., Ph.D.
• Associate Professor
  • Lin HAI KURAHARA, Ph.D.
• Assistant Professor
  • Tetsuo YAMASHITA, Ph.D.
  • Takeshi HASHIMOTO, Ph.D.
• Visiting Scientis
  • Mayumi HIRANO, Ph.D.
• Research Associate
  • Natsuko TSURUDOME, Ph.D.
• Administration
  • Yuki KAMATA

• Translational Physiology with a focus on aging, life-style related diseases, and refractory diseases such as pulmonary hypertension and inflammatory bowel disease. The goal is to contribute to developing innovative new preventive and therapeutic strategies based on profound understanding of underlying pathophysiology.
• Special interests are in the field of physiology and pathophysiology of proteinase-activated receptors, smooth muscle contraction, endothelial function, angiogenesis, metabolism and mitochondrial functions.

• Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells.
  Hashimoto T, Hirano K.
  Cell. Mol. Biol. Lett. 29, 45, 2024
• The therapeutic effect of proteinase-activated receptor-1 antagonist on colitis-associated carcinogenesis.
  Li X, Kurahara L-H, Zhao Z, Zhao F, Ishikawa R, Ohmichi K, Li G, Yamashita T, Hashimoto T, Hirano M, Sun Z, Hirano K.
  Cell. Mol. Gastroenterol. Hepatol. 18, 105-131, 2024
• Critical role of Rho proteins in myosin light chain di-phosphorylation during early phase of endothelial barrier disruption.
  Hirano M, Hirano K:
  J. Physiol. Sci. 72, 32, 2022

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