Biochemistry

Staff

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Prof. IWABU

Current Research Projects

  • Elucidation of the molecular basis of metabolic diseases, including diabetes- and obesity-related disorders, and development of therapeutic and drug discovery platforms (targeting membrane receptors such as AdipoR and lipid metabolic enzymes including PLAAT family proteins)
  • Exploration of dietary and nutritional strategies that contribute to healthy longevity
  • Development of novel exercise biomarkers utilizing AI and wearable devices

Recent Publications

  • The PLAAT family as phospholipid-related enzymes. Uyama T, et al. Prog Lipid Res. 98, 101331, (2025)
  • A monoclonal antibody activating AdipoR for type 2 diabetes and nonalcoholic steatohepatitis. Asahara N, et al. Sci Adv. 9, eadg4216 (2023)
  • PLAAT1 deficiency alleviates high-fat diet-induced hepatic lipid accumulation in mice. Rahman SMK, et al. FASEB J. 37, e23032 (2023)

Contact Information

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