Radiation Oncology

Basic and clinical research to improve quality and efficacy of intensity modulated radiation therapy (IMRT) by achieving highly-optimized dose distributions and to promote its application to a wide range of cancers, including head and neck cancers, malignant glioma, prostate cancers, and uterine cervical cancers.
Studies on quality assurance of verification and high precision radiation delivery by image-guided radiotherapy (IGRT) using real-time imaging technology.
Studies on contouring targets and risk organs by automatic and deformable image registration technology as well as image fusion technology using CT, MRI, and various molecular imagings.
Studies on mechanism of treatment-related toxicity of normal tissues (i.e., radiation pneumonitis) and on its reduction via eliminating unnecessary dose by IMRT, IGRT, and respiratory gating technology.
Participation and co-operation in nationwide clinical research trialists group as follows:
- A registry of Nation Japanese Radiation Oncology Study Group: Intensity-modulated radiation therapy for prostate cancer (JROSG 17-5)

Feasibility of hippocampal dose–volume parameters associated with memory decline in intensity-modulated radiotherapy for supratentorial tumors.
Takahashi S, et al. Mol Clin Oncol. 14(3),53 (2021).
Correlation of Pathological Complete Response With Tumor Volume Reduction During Neoadjuvant Chemoradiotherapy in Lung Cancer.
Takahashi S, et al. Anticancer Res. 40(8),4327-4330 (2020).
Respiratory motion of lymph node stations in pancreatic cancer: Analyses using contrast-enhanced four-dimensional computed tomography.
Takahashi S, et al. Radiother Oncol. 128(3), 569-574 (2018).

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