International Medical Zoology
Staff
Assoc. Prof. ARAI
Current Research Projects
- Studies on biochemical and molecular mechanisms of malaria parasite development in the vector mosquito.
- Development of Plasmodium Mosquito Stage Culture (PMSC), by which infectious sporozoites are obtained without using vector mosquitoes.
- Development of a transmission-blocking antimalarial.
Representative Publications
- Potent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen.
Tanaka TQ, et al. Antimicrob. Agents Chemother. 59, 1389-1397 (2015).
- Suppressive effect of azithromycin on Plasmodium berghei mosquito stage development and apicoplast replication.
Shimizu S, et al. Malar. J. 9, 73 (2010).
- Male fertility of malaria parasites is determined by GCS1, a plant-type reproduction factor.
Hirai M, et al. Curr. Biol. 18, 607-613 (2008).
Contact Information
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