Orthopedic Surgery

Staff

2.jpg
Prof. ISHIKAWA


Education

The Department of Orthopedic Surgery at Kagawa University provides systematic lectures on almost all orthopedic surgical fields including traumatology, joint surgery, spine surgery, bone metabolism, hand surgery, rheumatic diseases, peripheral nerve surgery, microsurgery, and bone and soft tissue tumors as part of pre-graduate education. The lectures cover bone, joint, and spinal anatomy with easy-to-understand illustrations and provide education on diagnostic and therapeutic methods of kinesiology, which is essential not only for medical specialists but also for physicians in other departments.
In Medical Practice 1 in the fifth year, each group is assigned a patient with a representative disease, and the instructor provides detailed explanations of medical history, diagnostic imaging, surgical indications, surgical procedures, and postoperative care. During the practical training, mini-lectures, video training, and hands-on practice using simulated bones and simulators are incorporated to provide a wide variety of practical training content.
In Medical Practice 2 in the sixth year, students experience more advanced and practical surgical techniques, and depending on the situation, are encouraged to participate in orthopedic-related academic conferences to experience an atmosphere of learning the latest knowledge. 
In terms of post-graduate education, we have established and are implementing a detailed post-graduate clinical training program to train orthopedic specialists certified by the Japanese Orthopaedic Association.
We are committed to providing education based on EBM (evidence-based medicine), incorporating the latest findings, and passing on the skills and experience unique to surgeons (i.e., craftsmen) to the next generation.
Our slogan is "The practice of medicine is an art, based on science – by William Osler”. We aim to nurture "Surgeon-Scientists", orthopedic surgeons, who can provide better treatments based on science by confronting the problems of patients without being satisfied with the status quo.

Current research topics

1.Development of new treatment methods in cartilage tissue repair and regeneration
2.Development of a novel issue characterization method using light and color information in the field of orthopedic surgery
3.Relationship between the proliferative potential of cell growth factors in bone and soft tissue tumor cell lines
4.Research on the effects of molecularly targeted drugs on malignant bone and soft tissue tumors
5.Development of gene therapy for osteosarcoma
6.Evaluation of changes in bone calcification, bone microdamage density, and bone strength in osteoporosis
7.Evaluation of changes in bone calcification, bone microdamage density, and bone strength after long-term treatment in osteoporosis
8.Evaluation of bone mechanical properties associated with bone calcification
9.Evaluation of the effect of mechanical loading by vibratory load training on fracture prevention and fall prevention
10.Development of vascularized allogeneic bone grafting using biological fortification with autologous bone marrow cell source
11.Investigation of the mechanism of nerve regeneration in experimental spinal cord injury
12.Development of rehabilitation training using virtual reality

Current Research Projects

  • Regulation of malignant bone and soft tissue tumors genetic and molecular approach
  • Evaluation of bone calcification, bone microdamage density, and bone strength in osteoporosis and after long-term treatment with osteoporosis drugs
  • Investigation of novel treatment methods for tissue repair and regeneration in musculoskeletal field

Recent Publications

  • Negayama T, Iwata K, Shimamura M, Senda T, Mashiba T, Kaji Y, Yamamoto T. Total hip arthroplasty after rotational acetabular osteotomy for developmental dysplasia of the hip: a retrospective observational study. BMC Musculoskelet Disord. 2022 Jul 6;23(1):646. doi: 10.1186/s12891-022-05597-y. PMID: 35794611; PMCID: PMC9258082.
  • Yamaguchi K, Kaji Y, Nakamura O, Tobiume S, Nomura Y, Oka K, Yamamoto T. Bone Union Enhancement by bFGF-Containing HAp/Col in Prefabricated Vascularized Allo-Bone Grafts. J Reconstr Microsurg. 2021 May;37(4):346-352. doi: 10.1055/s-0040-1716854. Epub 2020 Sep 21. PMID: 32957154.
  • Ishibashi Y, Nakamura O, Yamagami Y, Nishimura H, Fukuoka N, Yamamoto T. Chloroquine Enhances Rapamycin-induced Apoptosis in MG63 Cells. Anticancer Res. 2019 Feb;39(2):649-654. doi: 10.21873/anticanres.13159. PMID: 30711941.

Contact Information