Cardiovascular Physiology

Staff

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Prof. HIKANO

Current Research Projects

  • Translational Physiology with a focus on aging, life-style related diseases, and refractory diseases such as pulmonary hypertension and inflammatory bowel disease. The goal is to contribute to developing innovative new preventive and therapeutic strategies based on profound understanding of underlying pathophysiology.
  • Special interests are in the field of physiology and pathophysiology of proteinase-activated receptors, smooth muscle contraction, endothelial function, angiogenesis, metabolism and mitochondrial functions.

 

Representative Publications

  • Critical role of Rho proteins in myosin light chain di-phosphorylation during early phase of endothelial barrier disruption.
    Hirano M, Hirano K:
    J. Physiol. Sci. 72, 32, 2022
  • Lactulose modulates the structure of gut microbiota and alleviates colitis-associated tumorigenesis.
    Hiraishi K, Zhao F, Kurahara LH, Li X, Yamashita T, Hashimoto T, Matsuda Y, Sun Z, Zhang H, Hirano K.
    Nutrients 14, 649, 2022
  • Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn.
    Kurahara LH, Hiraishi K, Yamamura A, Zhang Y, Abe K, Yahiro E, Aoki M, Koga K, Yokomise H, Go T, Ishikawa K, Zhang B, Kishi H, Kobayashi S, Aoki-Shoi N, Satoh T, Inoue R, Hirano K.
    J. Mol. Cell. Cardiol. 148, 50-62, 2020

Contact Information

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